The Hierarchical Order of Cardiovascular-Respiratory Coupling

Raschke, F.

doi:10.1007/978-1-4757-0360-3_13

Cited by 15 publications

(10 citation statements)

References 25 publications

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“…Coupling in humans was first demonstrated by Galli in 1924 [11] and subsequent work, primarily by two groups of German physiologists, helped describe and elucidate the phenomena further. Coupling was shown to correlate inversely with arousal, it is rarely present during activity and commonly present at rest and during sleep [7,22]. In 1967, Hinderling showed that coupling is maintained in patients fitted with cardiac pacemakers "just as intensely as in healthy persons" [13].…”

Section: Introductionmentioning

confidence: 99%

Cardioventilatory coupling in the anaesthetised rabbit, rat and guinea-pig

Larsen¹,

Galletly²

1999

Pfl�gers Archiv European Journal of Physiology

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Cardioventilatory coupling is a temporal coherence of respiratory and cardiac rhythms, seen in humans at rest, and during sleep and anaesthesia. In this study we compared the cardioventilatory coupling of anaesthetised rabbits, rats and guinea-pigs. Breathing two successive anaesthetic concentrations (1 or 2% isoflurane) we compared the effect of anaesthetic depth and species on (1) heart rate, (2) heart rate variability, (3) ventilatory rate (f), (4) ventilatory variability, (5) ratio HR/f, (6) degree of coupling (Shannon entropy of the distribution of intervals between inspiration and the preceding electrocardiographic R wave - the RI interval) and (7) coupling pattern, classified into four sub-patterns (I-IV) based upon inspection of the RI interval time series. Rabbits exhibited significantly less ventilatory variability and coupling than rats or guinea-pigs. The sub-pattern of coupling also differed between the three species. Rabbits showed coupling only when HR and f were close to integer ratios whereas other species coupled at non-integer ratios. Ventilatory variability in the rat and guinea-pig differed according to the pattern of coupling observed. Of the three species studied, the rat and guinea-pig demonstrated coupling most similar to that of anaesthetised human subjects. Anaesthetic concentration did not influence the pattern or degree of coupling.

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Section: Introductionmentioning

confidence: 99%

Cardioventilatory coupling in the anaesthetised rabbit, rat and guinea-pig

Larsen¹,

Galletly²

1999

Pfl�gers Archiv European Journal of Physiology

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“…Coupling is seen best under conditions of low arousal: sleep, sedation and general anaesthesia. The synchronization of gill movements to heart beats was first described in fish by Schoenlein in 1895, 3 the coupling of ventilation to heart beats in mammalian species by Coleman in 1921 4 and in humans by Galli in 1924. 3 The mechanism of CVC is thought to be triggering of inspiratory timing by arterial or intracranial pressor receptor afferents.…”

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confidence: 99%

Relationship between cardioventilatory coupling and respiratory sinus arrhythmia

Galletly¹,

Larsen²

1998

British Journal of Anaesthesia

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Recent studies have suggested a role for respiratory sinus arrhythmia in improving pulmonary gas transfer. However, the physiological role of cardioventilatory coupling is unknown. We have tested the hypothesis that cardioventilatory coupling aligns heart beats at positions of the ventilatory cycle where they are maximally affected by respiratory sinus arrhythmia (RSA). In 15 anaesthetized, spontaneously breathing subjects, we recorded continuously the timing of inspiration and the ECG. We then plotted the change in RR interval which occurred, as a result of RSA, after onset of inspiration (RSA plot). By comparing these RSA plots with the distribution of heart beats during the ventilatory cycle, we were able to examine the positioning of heart beats relative to acceleration of heart rate as a result of RSA. In all but two subjects we observed that during periods of strong cardioventilatory coupling, heart beats occurred at positions in the ventilatory cycle where they were maximally affected by RSA. In the presence of strong coupling, the shortest possible RR interval occurred during late inspiration, the longest possible RR interval occurred immediately before the start of inspiration. We suggest that cardioventilatory coupling may have a physiological role in optimizing RSA, perhaps to improve cardiopulmonary performance during sleep.

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“…As opposed to the synchronisation, which describes a phase-based relationship between systems, the coordination describes a time-based connection (e.g. between the time points of the onsets of respiratory cycles and the heart beats) and has been shown to play an important role for example in cardiorespiratory mechanisms [Ras86,Ras87,RH82].…”

Section: Synchronisation and Coordinationmentioning

confidence: 99%

Coupling analysis of transient cardiovascular dynamics

Müller

Riedl

Penzel

et al. 2013

Biomedizinische Technik/Biomedical Engineering

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DissertationAmong the systems mentioned above, especially the cardiovascular system, whose complex behaviour is determined through many overlapping regulatory processes, is an ongoing researchtopic. An important section of this field comprises the interactions between the beat-to-beat intervals and the blood pressure, which on the one hand are at least known partially and on the other hand are controversially discussed.In this work, initially some existing coupling measures and their fields of application are introduced. One trait these measures have in common is the requirement of stationary time series to ensure their applicability. Therefore, in the course of this thesis a possibility to extend these measures is presented, which allows a coupling analysis with a high temporal resolution and thus also the analysis of transient, nonstationary events.The extension is based on the use of ensembles of time series and the calculation of the respective measures across these ensembles instead of across time. This allows for a temporal resolution of the same order of magnitude as the sampling rate in the original signal. The resolution only depends on the kind of coupling analysis method employed.The ensemble extension is applied to different coupling measures already successfully employed under difficult circumstances like high noise levels or short time series. For comparison, two simpler coupling measures are used. To begin with, the regarded tools are tested on various theoretical models and under different conditions. This is followed by a coupling analysis of cardiovascular time series recorded during transient events. The results on the one hand confirm topical study outcomes and on the other hand deliver new insights, which will allow to extend and improve cardiovascular system models in the future. Prediction methods based on these models will then be able to provide new diagnostic techniques and treatment procedures for cardiovascular diseases, thus contributing to health preservation in humans.

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The Hierarchical Order of Cardiovascular-Respiratory Coupling

Cited by 15 publications

References 25 publications

Cardioventilatory coupling in the anaesthetised rabbit, rat and guinea-pig

Cardioventilatory coupling in the anaesthetised rabbit, rat and guinea-pig

Relationship between cardioventilatory coupling and respiratory sinus arrhythmia

Coupling analysis of transient cardiovascular dynamics

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