“…This radiologic finding is nonspecific but highly suggestive of angioinvasive fungal infections, most commonly IPA [33]. A broad range of conditions can also be associated with the halo sign, including malignant diseases (hemorrhagic metastases of angiosarcoma or choriocarcinomas, lymphomas, acute leukemia, Kaposi's sarcoma), bacterial infections (tuberculosis and actinomycosis), viral infections (cytomegalovirus, herpes simplex virus, or varicella-zoster virus), Wegener granulomatosis, and transbronchial biopsy [33,34].…”