The Gut Microbiome May Help Address Mental Health Disparities in Hispanics: A Narrative Review

Vera-Urbina, Fernando; Santos-Torres, María F. Dos; Godoy-Vitorino, Filipa; Torres-Hernández, Bianca A.

doi:10.3390/microorganisms10040763

Cited by 3 publications

(2 citation statements)

References 142 publications

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“…The compositional and functional disequilibrium of the gut ecosystem, known as dysbiosis, is accountable for the disclosure of several diseases from neurological affections [ 130 , 131 ], to the liver [ 132 ], cardiovascular [ 133 ], autoimmune diseases [ 134 ], food allergies [ 135 ], diabetes [ 136 ], obesity [ 137 ], cancer development [ 138 ], decreased calcium absorption [ 139 ], and even influence the severity of infectious disease such as COVID-19 [ 140 , 141 ]. The applicability of these compounds can exert an alleged “prebiotic” outcome on the health of humans and animals.…”

Section: Health Benefits Of Pegsmentioning

confidence: 99%

Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Pascuta

Varvara

Teleky

et al. 2022

Gels

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Nowadays, edible materials such as polysaccharides have gained attention due to their valuable attributes, especially gelling property. Polysaccharide-based edible gels (PEGs) can be classified as (i) hydrogels, (ii) oleogels and bigels, (iii) and aerogels, cryogels and xerogels, respectively. PEGs have different characteristics and benefits depending on the functional groups of polysaccharide chains (e.g., carboxylic, sulphonic, amino, methoxyl) and on the preparation method. However, PEGs are found in the incipient phase of research and most studies are related to their preparation, characterization, sustainable raw materials, and applicability. Furthermore, all these aspects are treated separately for each class of PEG, without offering an overview of those already obtained PEGs. The novelty of this manuscript is to offer an overview of the classification, definition, formulation, and characterization of PEGs. Furthermore, the applicability of PEGs in the food sector (e.g., food packaging, improving food profile agent, delivery systems) and in the medical/pharmaceutical sector is also critically discussed. Ultimately, the correlation between PEG consumption and polysaccharides properties for human health (e.g., intestinal microecology, “bridge effect” in obesity, gut microbiota) are critically discussed for the first time. Bigels may be valuable for use as ink for 3D food printing in personalized diets for human health treatment. PEGs have a significant role in developing smart materials as both ingredients and coatings and methods, and techniques for exploring PEGs are essential. PEGs as carriers of bioactive compounds have a demonstrated effect on obesity. All the physical, chemical, and biological interactions among PEGs and other organic and inorganic structures should be investigated.

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Section: Health Benefits Of Pegsmentioning

confidence: 99%

Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Pascuta

Varvara

Teleky

et al. 2022

Gels

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show abstract

“…Among them, Bacteroidetes and Firmicutes are the most important, followed by Proteobacteria, Fusobacteria, Tenericutes, Actinobacteria and Verrucomicrobia, accounting for 90% of the total microbial population in humans (Gomaa, 2020). In a healthy state, the GM is in ecological balance, showing a high diversity and rich microbial population, which plays a variety of important roles in host, such as digestion, metabolism, immune regulation, anti-aging and emotional cognition (Vera-Urbina et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Gut microbiota, pathogenic proteins and neurodegenerative diseases

Wei

Wang

et al. 2022

Front. Microbiol.

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As the world’s population ages, neurodegenerative diseases (NDs) have brought a great burden to the world. However, effective treatment measures have not been found to alleviate the occurrence and development of NDs. Abnormal accumulation of pathogenic proteins is an important cause of NDs. Therefore, effective inhibition of the accumulation of pathogenic proteins has become a priority. As the second brain of human, the gut plays an important role in regulate emotion and cognition functions. Recent studies have reported that the disturbance of gut microbiota (GM) is closely related to accumulation of pathogenic proteins in NDs. On the one hand, pathogenic proteins directly produced by GM are transmitted from the gut to the central center via vagus nerve. On the other hand, The harmful substances produced by GM enter the peripheral circulation through intestinal barrier and cause inflammation, or cross the blood–brain barrier into the central center to cause inflammation, and cytokines produced by the central center cause the production of pathogenic proteins. These pathogenic proteins can produced by the above two aspects can cause the activation of central microglia and further lead to NDs development. In addition, certain GM and metabolites have been shown to have neuroprotective effects. Therefore, modulating GM may be a potential clinical therapeutic approach for NDs. In this review, we summarized the possible mechanism of NDs caused by abnormal accumulation of pathogenic proteins mediated by GM to induce the activation of central microglia, cause central inflammation and explore the therapeutic potential of dietary therapy and fecal microbiota transplantation (FMT) in NDs.

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A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration

Reynoso-García¹,

Miranda-Santiago

Meléndez-Vázquez

et al. 2022

Front. Syst. Biol.

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Humans are supra-organisms co-evolved with microbial communities (Prokaryotic and Eukaryotic), named the microbiome. These microbiomes supply essential ecosystem services that play critical roles in human health. A loss of indigenous microbes through modern lifestyles leads to microbial extinctions, associated with many diseases and epidemics. This narrative review conforms a complete guide to the human holobiont—comprising the host and all its symbiont populations- summarizes the latest and most significant research findings in human microbiome. It pretends to be a comprehensive resource in the field, describing all human body niches and their dominant microbial taxa while discussing common perturbations on microbial homeostasis, impacts of urbanization and restoration and humanitarian efforts to preserve good microbes from extinction.

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The Gut Microbiome May Help Address Mental Health Disparities in Hispanics: A Narrative Review

Cited by 3 publications

References 142 publications

Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Polysaccharide-Based Edible Gels as Functional Ingredients: Characterization, Applicability, and Human Health Benefits

Gut microbiota, pathogenic proteins and neurodegenerative diseases

A complete guide to human microbiomes: Body niches, transmission, development, dysbiosis, and restoration

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