The Global Burden of Surgical Management of Osteoporotic Fractures

Tarrant, Seth M.; Balogh, Zsolt J.

doi:10.1007/s00268-019-05237-y

Cited by 39 publications

(31 citation statements)

References 149 publications

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“…3a, 3b, 4a, 4b, 5a, 5b)s. In light of recent literature, internal xation with a medial and lateral plate appears to be the gold standard in the treatment of distal femur fractures in the elderly population, which may bene t from early loading and mobilization in terms of lower mortality, inferior morbidity and overall better function [1] [36]. On the other side, if a TKA will be subsequently indicated, the surgeon could decide whether to perform a more familiar medial approach or a lateral one being not afraid of ischemic complications involving the patella and the adjacent soft tissues.…”

Section: Discussionmentioning

confidence: 99%

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“A Modified Anterolateral Swashbuckler Approach for Distal Femoral Fractures: Description and Outcomes”

Ghirardelli¹,

Touloupakis²,

Theodorakis³

et al. 2021

Preprint

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Background: The treatment of distal femur fractures represents a challenging task. General and local factors, including bone quality, articular surface involvement, fracture comminution, associated soft tissue injuries and ultimately fixation system, all play a role in the final clinical outcome. Current surgical approaches often undermine patellar vascularization and integrity of the extensor apparatus, not guaranteeing sufficient visualization of the medial condyle. This technical note presents the efficacy and safety a new surgical technique to address distal femoral fractures. Methods: The original "swashbuckler" surgical approach was modified in order to obtain a better visualization of the lateral and medial femoral condyles without affecting the knee extensor mechanism and the anastomotic arterial supply of the patella. This modified surgical approach was utilized in a consecutive series of patients presenting with a Müller AO 33 distal femur or periprosthetic fracture of the knee. The final outcome was recorded according to a functional evaluation scoring system.Results: Twelve patients (2 males and 10 females) with a mean age of 67,8 years (min. 18; max 90 years) were included in this series. The same, modified "swashbuckler" surgical approach was applied in all cases. Multiple internal fixation techniques, including a single lateral plate, a combination of a lateral and medial plate, a single lateral plate associated with lag screws, were used to obtain a satisfactory stabilization of the fracture site. All patients were reviewed at a minimum one-year follow up (median 15 months): all patients regained their level of activities of daily living. No major intraoperative or postoperative complications were recorded. Conclusions: The modified swashbuckler approach allows anatomical reduction and appropriate fixation with minimal severance of the blood supply to the patella and ensures rapid weight bearing resumption thanks to an intact extensor mechanism.

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Section: Discussionmentioning

confidence: 99%

“…xation system and associated soft tissue injuries, all play a role in the nal clinical result [1] [2].…”

Section: Introductionmentioning

confidence: 99%

“A Modified Anterolateral Swashbuckler Approach for Distal Femoral Fractures: Description and Outcomes”

Ghirardelli¹,

Touloupakis²,

Theodorakis³

et al. 2021

Preprint

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“…Osteoporosis is a major global risk factor for fractures and subsequent pain, disability, institutionalization, and mortality 1,2 . It may also be a cardiovascular risk factor 3 .…”

Section: Introductionmentioning

confidence: 99%

“…It may also be a cardiovascular risk factor 3 . The considerable social burden of osteoporosis also comes with large economic costs 2,4 …”

Section: Introductionmentioning

confidence: 99%

Effect of patient‐led cooperative follow‐up by general practitioners and community pharmacists on osteoporosis treatment persistence

et al. 2021

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Aim Osteoporosis is a major risk factor for fractures. Poor persistence with osteoporosis medication hampers outcomes. This study assessed whether encouraging the formation of patient‐led follow‐up cooperatives between general practitioners (GPs) and community pharmacists improved medication persistence. Methods All consecutive patients who attended an osteoporosis patient education program were invited to participate. They were given a logbook containing questionnaires they would bring to 6‐monthly visits to their GP and pharmacist. The effect of this 3‐year cooperative follow‐up on persistence with medication and lifestyle changes was assessed. Results In total, 121 patients (average age, 67 years; 93% female) participated. Poor cooperation between GPs and pharmacists was noted. Nevertheless, medication persistence ranged from 83% to 91% over the 6 visits. However, since patient drop‐out rates were high and questionnaire return rates were low, a post‐study medical chart review was performed. This confirmed that persistence was high (74%‐83%) at 3 years post‐enrollment, even for oral bisphosphonate‐treated patients (73%‐76%). However, adoption of anti‐osteoporosis lifestyle changes was poor throughout the study: one‐ to two‐thirds of the patients did not alter their diet, physical activity, or surroundings to prevent falls. Conclusion One study goal, namely, to encourage GPs and pharmacists to cooperate in patient follow‐up, was not achieved. However, high medication persistence was observed. This may reflect the education program, patient empowerment, personalized attention from study personnel, and being in a study. Patient‐centered approaches can thus significantly increase medication persistence in osteoporosis. Ongoing education may be needed to improve patient adoption of and persistence with lifestyle changes.

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“…[ 2 – 4 ] With the advent of aging society and peoples life expectancy, the cost of fracture care caused by osteoporosis will increase the medical burden of the whole society. [ 5 – 7 ] According to statistics, there are 10 million cases of bone fracture caused by osteoporosis worldwide every year, and two-thirds of them are women. [ 8 ] Organizations such as the IOF are also studying the epidemiology of osteoporosis and fractures.…”

Section: Introductionmentioning

confidence: 99%

Comparison of efficacy and safety of Chinese patent medicine in the treatment of postmenopausal osteoporosis

Zhao²,

Wang

et al. 2020

Medicine

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Background: Postmenopausal osteoporosis (PMOP) is the focus and difficult problem in the world at present, and we found that Chinese patent medicine(CPM) shown a more miraculous effect. Many kinds of Chinese patent medicine have been proved to be effective in the treatment of this disease, but it is still unclear which kind of Chinese patent medicine has the best effect. Therefore, we propose a network meta-analysis (NMA) protocol to observe the efficacy of various CPM for this disease and provide guidance for clinical practice. Methods: We will use the NMA method to complete this study. First, all the randomized controlled trials of CPM or CPM combined with western medicine in the treatment of PMOP were collected by searching all online Chinese and English databases. The information time limit is from the establishment of the database to August 30, 2020. Then 2 staff members will sift through all the literature and analyze the data using Stata and Winbugs. Results: Through this analysis, we will observe and rank the clinical effects of different CPM for PMOP. The main evaluation indexes include: New fracture, Quality of life, Severe side effects, Death from all causes. Secondary outcome indicators include Bone Mineral density, clinical efficiency, and some laboratory indicators, such as estradiol, serum calcium, serum, etc. Conclusion: This study will rank the therapeutic effects of various proprietary Chinese medicines in the treatment of PMOP, which will be helpful in improving the PMOP treatment regimen. INPLASY registration number: INPLASY202090047.

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The Global Burden of Surgical Management of Osteoporotic Fractures

Cited by 39 publications

References 149 publications

“A Modified Anterolateral Swashbuckler Approach for Distal Femoral Fractures: Description and Outcomes”

“A Modified Anterolateral Swashbuckler Approach for Distal Femoral Fractures: Description and Outcomes”

Effect of patient‐led cooperative follow‐up by general practitioners and community pharmacists on osteoporosis treatment persistence

Comparison of efficacy and safety of Chinese patent medicine in the treatment of postmenopausal osteoporosis

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