The German version of the chronic urticaria quality‐of‐life questionnaire: factor analysis, validation, and initial clinical findings

Młynek, A.; Magerl, Markus; Hanna, Michael; Lhachimi, Stefan K.; Baiardini, Ilaria; Canonica, Giorgio Walter; Brzoza, Zenon; Kasperska−Zając, Alicja; Rogala, Barbara; Zalewska-Janowska, Anna; Zuberbier, Torsten; Maurer, Marcus

doi:10.1111/j.1398-9995.2008.01920.x

Cited by 151 publications

(144 citation statements)

References 31 publications

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“…Takie cechy psychometryczne spra wiają, że jest to dobre narzędzie do oceny uszczerbku na zdrowiu w przebiegu PPS. Do chwili obecnej kwe stionariusz został przetłumaczony i zatwierdzony do stosowania w języku niemieckim, hiszpańskim, pol skim, tureckim, greckim, bułgarskim, portugalskim (odmiana europejska i brazylijska), a inne wersje języ kowe poddawane są aktualnie walidacji [24][25][26][27][28]. Do stępne są także testy dla pacjentów z objawami obrzę ku naczynioruchowego [29].…”

Section: Aspekty Patofizjologiczneunclassified

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

Zuberbier¹,

Aberer²,

Asero³

et al. 2015

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Section: Aspekty Patofizjologiczneunclassified

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

Zuberbier¹,

Aberer²,

Asero³

et al. 2015

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“…The existence of a disease-specific questionnaire like the CU-Q 2 oL facilitates the investigation of the parameters that drive HRQoL impairment. The CU-Q 2 oL is currently the only available CSU-specific quality of life instrument and is already available in several language versions [11,12,13,14,15,16]. The aim of this study was to develop a Greek version of the CU-Q 2 oL and to assess the relation between disease activity and HRQoL impairment.…”

Section: Introductionmentioning

confidence: 99%

Disease Activity Only Moderately Correlates with Quality of Life Impairment in Patients with Chronic Spontaneous Urticaria

Koti¹,

Weller²,

Makris³

et al. 2013

Dermatology

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Background: The impact of chronic spontaneous urticaria (CSU) on health-related quality of life (HRQoL) is widely held to be mainly influenced by disease activity and comorbidities. Objective: To assess the correlation between disease activity and HRQoL impairment by using validated disease-specific instruments. Methods: The Chronic Urticaria Quality of Life Questionnaire (CU-Q₂oL) was translated into Greek and subsequently applied to 110 CSU patients along with the Dermatology Life Quality Index and the Urticaria Activity Score. After the validity and reliability of the Greek CU-Q₂oL had been determined, we assessed the relation between disease activity and HRQoL impairment by computing correlations as well as by performing multiple regression analysis. Results: Exploratory factor analysis revealed a six-scale structure of the Greek CU-Q₂oL that explained 67.9% of its total variance. The internal consistency was satisfactory with Cronbach's α >0.7. Disease activity was the only predictor of quality of life impairment, but it only moderately correlated with the CU-Q₂oL total score (r = 0.40, p < 0.0001). Conclusion: Our results suggest that there are additional factors to disease activity that are responsible for the pronounced reduction of HRQoL in CSU, and this supports the recommendation to assess and monitor both disease activity and quality of life in CSU patients.

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“…These findings are in agreement with data published in the literature. 15,28,30 In the present study, the SF-36 domains indicative of greater impairment of quality of life were: rolephysical and vitality. The role-physical domain reflects 24,26 In the comparison of the scores of the questionnaires between the clinical types of chronic urticaria (COU, PU and MU), no statistically significant differences were found between the various types and it was impossible to conclude whether one may affect quality of life to a greater extent than another.…”

Section: 28-30mentioning

confidence: 48%

Estudo da qualidade de vida nos pacientes com urticária crônica

Souza

Rotta

et al. 2011

An. Bras. Dermatol.

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BACKGROUND: Chronic urticaria affects patients by interfering with their daily activities, damaging their self-esteem and negatively affecting their interpersonal relationships. Healthcare professionals may underestimate the impact of the condition on patients' quality of life. OBJECTIVES: To evaluate quality of life using one generic and one disease-specific health-related quality of life instrument; to compare quality of life between the different clinical types of chronic urticaria and to evaluate whether angioedema further impairs quality of life. METHODS: Sixty-two patients with chronic urticaria, who had had signs or symptoms of the disease within the preceding week, were divided into groups according to whether they had ordinary chronic urticaria, physical chronic urticaria or mixed chronic urticaria. RESULTS: There was a predominance of women in this study (72.6%). The mean age of patients was 39.8 years and angioedema was associated with chronic urticaria in 75.8% of cases. Associated angioedema was more commonly found in patients with ordinary chronic urticaria (p=0.011) and in women (p=0.024). With respect to the different clinical types, 32.3% of the patients had ordinary chronic urticaria, 27.4% had physical chronic urticaria and 40.3% had mixed chronic urticaria. Mean overall score for the disease-specific questionnaire was 10.4. In this questionnaire, the most affected domains were "symptoms and feelings" and "daily activities", while the most affected domains in the SF-36 were "physical role" and "vitality". Quality of life was found to be impaired in women, in patients of up to 30 years of age, in those attending a first consultation, in those with higher education levels, in patients who had had the disease for up to one year and in those with angioedema. CONCLUSIONS: Chronic urticaria affects quality of life, as measured using a disease-specific questionnaire and a generic questionnaire. There was no statistically significant difference between the clinical types. The presence of angioedema impaired patients' quality of life even further. There was a statistically significant correlation between the scores obtained using the disease-specific questionnaire and those obtained using the generic questionnaire. Keywords: Angioedema; Quality of life; Questionnaires; Sickness impact profile; Urticaria Resumo: FUNDAMENTOS: A urticária crônica compromete o doente por interferir nas atividades diárias, prejudicar a autoestima e as relações interpessoais. Os profissionais de saúde subestimam seu impacto na qualidade de vida dos doentes. OBJETIVOS: Avaliar a qualidade de vida com questionário específico e genérico. Compará-la entre os tipos clínicos de urticária crônica e avaliar se o angioedema piora a qualidade de vida. MÉTODOS: Participaram 62 doentes com urticária crônica, com sinais e sintomas da doença até 7 dias da consulta, que foram divididos em urticária crônica comum, urticária crônica física e urticária crônica mista. RESULTADOS: Observou-se predominância de mulheres (72,6%), idade m...

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The German version of the chronic urticaria quality‐of‐life questionnaire: factor analysis, validation, and initial clinical findings

Cited by 151 publications

References 31 publications

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

Disease Activity Only Moderately Correlates with Quality of Life Impairment in Patients with Chronic Spontaneous Urticaria

Estudo da qualidade de vida nos pacientes com urticária crônica

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