The genus Sida L. – A traditional medicine: Its ethnopharmacological, phytochemical and pharmacological data for commercial exploitation in herbal drugs industry

Dinda, Biswanath; Das, Niranjan; Dinda, Subhajit; Dinda, Manikarna; SilSarma, Indrajit

doi:10.1016/j.jep.2015.10.027

Cited by 70 publications

(41 citation statements)

References 138 publications

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“…Não foram encontrados na literatura estudos de histoquímica com a planta. A maior parte das investigações fitoquímicas com S. rhombifolia e outras espécies de Sida encontradas na literatura foram realizadas com as partes aéreas da planta (CHAVES et al, 2013;DINDA et al, 2015). De acordo com alguns trabalhos de revisão sobre o gênero, os grupos químicos predominantes em Sida são os alcaloides, flavonoides e ecdisteroides (HALDE;WAKE;PATIL, 2011;DINDA et al, 2015).…”

Section: Resultsunclassified

“…A maior parte das investigações fitoquímicas com S. rhombifolia e outras espécies de Sida encontradas na literatura foram realizadas com as partes aéreas da planta (CHAVES et al, 2013;DINDA et al, 2015). De acordo com alguns trabalhos de revisão sobre o gênero, os grupos químicos predominantes em Sida são os alcaloides, flavonoides e ecdisteroides (HALDE;WAKE;PATIL, 2011;DINDA et al, 2015). O principal alcaloide isolado no gênero é a efedrina (PRAKASH;VARMA;GHOSAL, 1981;CHATTERJEE;KUMAR;CHATTOPADHYAY, 2013).…”

Section: Resultsunclassified

“…possui distribuição predominantemente pantropical, incluindo cerca de 250 gêneros e 4.200 espécies (JOLY, 1985;LORENZI, 2005). As plantas do gênero Sida L. ocorrem amplamente como ervas daninhas em pastagens de regiões tropicais e subtropicais do mundo (DINDA et al, 2015). No Brasil, são encontradas 103 espécies, dentre elas Sida rhombifolia L. (FLORA DO BRASIL, 2019).…”

Section: Introductionunclassified

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CARACTERIZAÇÃO ANATÔMICA E HISTOQUÍMICA DA LÂMINA FOLIAR DE SIDA rhombifolia L.

Sá¹,

Magalhães²,

Randau³

2020

Avanços Científicos, Tecnológicos E De Inovação Na Botânica

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Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição 4.0 Internacional (CC BY 4.0). O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais.

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Section: Resultsunclassified

Section: Introductionunclassified

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CARACTERIZAÇÃO ANATÔMICA E HISTOQUÍMICA DA LÂMINA FOLIAR DE SIDA rhombifolia L.

Sá¹,

Magalhães²,

Randau³

2020

Avanços Científicos, Tecnológicos E De Inovação Na Botânica

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“…16 Various studies reported that S. rhombifolia showed cytotoxic, anti-bacterial, anti-inflammatory, antipyretic and antinociceptive activities. [17][18][19] Phytochemical investigation revealed presence of alkaloids, flavonoids and phenolic compounds in aerial parts of S. rhombifolia. 20 Recently four alkaloids viz.…”

Section: Introductionmentioning

confidence: 99%

Modulation Activity of Sida Cordifolia L. And Sida Rhombifolia L. In Staphylococcus Aureus Sa-1199 B

Ahirrao¹,

Tambat²,

Kamboj³

et al. 2019

Int. Res. J. Pharm.

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Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for several infections in humans. The infections caused by this bacterial strain are difficult to treat due to resistance of MRSA to clinically used antibiotics. Over past two decades medicinal plant extracts and their phytoconstituents have been reported to possess modulation and efflux pump inhibitory (EPI) activity against MRSA strains. Sida cordifolia aerial parts, roots and Sida rhombifolia aerial parts have been reported to be used in Ayurveda for several ailments including bacterial/fungal infections. Based on this information and in continuation of our efforts to discover EPIs from Indian medicinal plants, we describe modulation activity of methanol extracts of aerial parts and roots of S. cordifolia and S. rhombifolia and alkaloid-rich fraction prepared from methanol extracts. Methanol extract of S. cordifolia and S. rhombifolia aerial parts showed 4-fold reduction each in MIC of norfloxacin at 125 µg/mL concentration whereas alkaloid-rich fraction of both the plants did not show any reduction in MIC of norfloxacin. Fractionation of bioactive MeOH extract of S. cordifolia aerial resulted in isolation and characterization of 8 compounds including 2 alkaloids, 5 flavonoids and 1 coumarin compound whereas LC-MS analysis of alkaloid-rich fraction of S. rhombifolia aerial parts revealed presence of alkaloids including cryptolepine and 11-methoxyquindoline. Although the methanol extracts of aerial parts of S. cordifolia and S. rhombifolia showed weak modulatory activity in NorA over expressed S. aureus 1199B strain, the present study helped to assess EPI activity potential of these plants.

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“…Fascinatingly, different parts of this plant have been used by the tribes located in India to treat the nervous disorder, reproductive problems, renal problems and rheumatism 3,4 . Furthermore, the plant also possesses antimalarial, antibacterial, antiinflammatory, analgesic and hepatoprotective properties 5,6 . Even in countries outside India like Nigeria, the extract prepared from leaves, seeds, and stems of Sida acuta is used as an antihypertensive agent in different solvent combinations 7 .…”

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confidence: 99%

Untitled

2019

IJPSR

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Sida acuta is one of the medically active plants used for the treatment of multifaceted diseases. However, an elaborated investigation on the phytochemical composition of the ethanolic extract of the leaves of this plant is yet to be deciphered. So, in this quantification of phytochemicals, in-vitro free radical scavenging activity, enzymatic and non-enzymatic antioxidant levels in the fresh leaves, HPTLC fingerprinting and GC-MS analysis in the ethanolic extract of Sida acuta leaves were done. In-vitro antioxidant activities were assayed using DPPH, ABTS, nitric oxide, hydroxyl radical and ferric ions, while ascorbic acid is used as the standard. The results indicated the presence of flavonoids, tannins, phenols, and alkaloids in a reasonably good amount which has substantiated the results of HPTLC. All the tested antioxidants were present prominently in the leaves, specifically catalase and glutathione peroxidase, which may be responsible for the prominent radical scavenging tendency of the extract against the tested free radicals. The GC-MS analysis observed the presence of 35 different compounds each belonging to different classes such as sterols, flavonoids, terpenes, heterocyclic aromatic compounds, phenols, fatty acids, vitamins, alkaloids, and sesquiterpenoids. The results indicate that the ethanolic extract of Sida acuta leaves collected from the Tuticorin District of Tamil Nadu is an effective scavenger of free radicals and has the potential to be used as a natural antioxidant which is attributable to the rich presence of its secondary metabolites.

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The genus Sida L. – A traditional medicine: Its ethnopharmacological, phytochemical and pharmacological data for commercial exploitation in herbal drugs industry

Cited by 70 publications

References 138 publications

CARACTERIZAÇÃO ANATÔMICA E HISTOQUÍMICA DA LÂMINA FOLIAR DE SIDA rhombifolia L.

CARACTERIZAÇÃO ANATÔMICA E HISTOQUÍMICA DA LÂMINA FOLIAR DE SIDA rhombifolia L.

Modulation Activity of Sida Cordifolia L. And Sida Rhombifolia L. In Staphylococcus Aureus Sa-1199 B

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