The Genus Ochrobactrum as Major Opportunistic Pathogens

Ryan, Michael P.; Pembroke, J. Tony

doi:10.3390/microorganisms8111797

Cited by 66 publications

(86 citation statements)

References 160 publications

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“…In contrast, Uruburuella suis , a novel species within the Neisseriaceae family, can be isolated from the lungs and hearts of different animals with lesions of pneumonia and pericarditis, respectively [ 42 ]. Ochromobactrum intermedium is an opportunistic pathogen especially found in hospital environments, and since 1999 seven cases have been reported due hospital-acquired infections [ 43 ], mainly related to immunocompromised patients with bacteremia, endophthalmitis, and pyogenic liver abscess [ 44 ].…”

Section: Discussionmentioning

confidence: 99%

An Update on Wastewater Multi-Resistant Bacteria: Identification of Clinical Pathogens Such as Escherichia coli O25b:H4-B2-ST131-Producing CTX-M-15 ESBL and KPC-3 Carbapenemase-Producing Klebsiella oxytoca

Mesquita

Ribeiro

Silva³

et al. 2021

Microorganisms

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Wastewater treatment plants (WWTPs) are significant reservoirs of bacterial resistance. This work aims to identify the determinants of resistance produced by Gram-negative bacteria in the influent and effluent of two WWTPs in Portugal. A total of 96 wastewater samples were obtained between 2016 and 2019. The numbers of total aerobic and fecal contamination bacteria were evaluated, and genomic features were searched by polymerase chain reaction (PCR) and Next-Generation Sequencing (NGS). Enterobacteriaceae corresponded to 78.6% (n = 161) of the 205 isolates identified by 16sRNA. The most frequent isolates were Escherichia spp. (57.1%, n = 117), followed by Aeromonas spp. (16.1%, n = 33) and Klebsiella spp. (12.7%, n = 26). The remaining 29 isolates (14.1%) were distributed across 10 different genera. Among the 183 resistant genes detected, 54 isolates produced extended spectrum β-lactamases (ESBL), of which blaCTX-M-15 was predominant (37 isolates; 68.5%). A KPC-3 carbapenemase-producing K. oxytoca was identified (n = 1), with blaKPC-3 included in a transposon Tn4401 isoform b. A higher number of virulence genes (VG) (19 genes) was found in the E. coli 5301 (O25b-ST131-B2) isolate compared with a commensal E. coli 5281 (O25b-ST410-A) (six genes). Both shared five VG [Enterobactin; Aerobactin, CFA/1 (clade α); Type1 (clade γ1); Type IV]. In conclusion, this work highlights the role of relevant clinical bacteria in WWTPs, such as KPC-3-producing K. oxytoca, and, for the first time, a CTX-M-15-producing Ochromobactrum intermedium, a human opportunistic pathogen, and a SED-1-producing Citrobacter farmeri, an uncommon CTX-M-type extended-spectrum beta-lactamase.

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Section: Discussionmentioning

confidence: 99%

An Update on Wastewater Multi-Resistant Bacteria: Identification of Clinical Pathogens Such as Escherichia coli O25b:H4-B2-ST131-Producing CTX-M-15 ESBL and KPC-3 Carbapenemase-Producing Klebsiella oxytoca

Mesquita

Ribeiro

Silva³

et al. 2021

Microorganisms

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“…It is resistant to multiple families of antibiotics such as ß-lactum including penicillins, cephalosporins, and sometimes carbapenems. This makes treatment of Ochrobactrum bacteria often challenging, with most strains susceptible to fluoroquinolones, aminoglycosides, carbapenems, and trimethoprim-sulfamethoxazole (TMP-SMX) [4,6,[16][17][18][19].…”

Section: Discussionmentioning

confidence: 99%

“…The Ochrobactrum genus was first identified in 1988. It was previously categorized as the Centers for Disease Control and Prevention (CDC) group Vd 1-2 [1][2][3][4]. Ochrobactrum species can be found in the environment such as water, soil, animals, and plants, as well as in polluted environments [1,5].…”

Section: Introductionmentioning

confidence: 99%

A Case of Ochrobactrum intermedium Bacteremia Secondary to Cholangitis With a Literature Review

Kassab¹,

Sarsam²,

Affas³

et al. 2021

Cureus

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“…The relatively abundant bacterial genera in C1 is Ochrobactrum (84.61%), and the proportion of added bacteria is: Bacillus (1.89%), Pseudomonas (0.24%), Paenibacillus (0.01%).Similarly, Ochrobactrum also belongs to the Proteobacteria , and several Ochrobactrum spp. have been investigated for their potential to degrade xenobiotic pollutants and for heavy metal detoxification under a variety of environmental conditions (38). Moreover, the odour of group C in the early stage of composting was significantly smaller than that of group A.…”

Section: Resultsmentioning

confidence: 99%

“…Many species of Burkholderia are opportunistic pathogens, such as Burkholderia pseudomallei that causes melioidosis (35) and Burkholderia cepacia that causes cystic fibrosis in human lungs (36,37). The relatively abundant bacterial genera in C1 is Ochrobactrum (38). Moreover, the odour of group C in the early stage of composting was significantly smaller than that of group A.…”

Section: Analysis Of Bacteria Composition During Composting Process Amentioning

confidence: 95%

Changes and composition of microbial community during aerobic composting of household food waste

Jin

Feng

et al. 2021

Preprint

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In order to explore the effect of added bacteria on microbial community and determine the dominant bacteria in the aerobic composting process of household food waste (HFW), two groups of HFW composting experiments were conducted for 30 days. The final degradation rates of the two groups were 69.95% (group A, natural composting) and 73.52% (Group C, composting with added bacteria), respectively. 16S rRNA high-throughput sequencing was used to analyze the changes of microbial community in the composting process. As the result displays, at the classification of phylum level?the relatively abundant bacteria of two groups were Firmicutes, Proteobacteria and Cyanobacteria. At the classification of genus level, Pediococcus is the dominant bacteria of group A, which performed better in maintaining the microbial community stable in the later stage of composting, while Weissella accounted for a relatively large proportion of group C and behaved well in promoting the final degradation rate of composting. The proportion of Ochrobactrum in the early stage of group C is considerable and it is closely related to the removal of odour during composting. The relative abundance of added bacteria was always in a rather low level?suggested that the way they affect the composting process is to change the proportion of dominant bacteria in different stage of composting. This experiment provides an important reference for improving the microbial degradation efficiency of HFW .

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The Genus Ochrobactrum as Major Opportunistic Pathogens

Cited by 66 publications

References 160 publications

An Update on Wastewater Multi-Resistant Bacteria: Identification of Clinical Pathogens Such as Escherichia coli O25b:H4-B2-ST131-Producing CTX-M-15 ESBL and KPC-3 Carbapenemase-Producing Klebsiella oxytoca

An Update on Wastewater Multi-Resistant Bacteria: Identification of Clinical Pathogens Such as Escherichia coli O25b:H4-B2-ST131-Producing CTX-M-15 ESBL and KPC-3 Carbapenemase-Producing Klebsiella oxytoca

A Case of Ochrobactrum intermedium Bacteremia Secondary to Cholangitis With a Literature Review

Changes and composition of microbial community during aerobic composting of household food waste

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