The genus Lindera: a source of structurally diverse molecules having pharmacological significance

Yuan, Chengfu; Xuan, Bianfei; Peng, Bing; Li, Chun; Chai, Xingyun; Tu, Pengfei

doi:10.1007/s11101-015-9432-2

Cited by 49 publications

(63 citation statements)

References 134 publications

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“…(Table 1) showed signals equivalent to 39 carbons including kaempferol moiety, two β-glucopyranosyl moieties, and two α-rhamnopyranosyl moieties. The attachment of sugar moieties was confirmed on the basis of the 2D NMR spectra including 1 H- 1 (Table 1) showed signals equivalent to 39 carbons including kaempferol moiety, two β-glucopyranosyl moieties, and two α-rhamnopyranosyl moieties. The attachment of sugar moieties was confirmed on the basis of the 2D NMR spectra including 1 H-1 H COSY, HMQC, HMBC, and TOCSY.…”

Section: Resultsmentioning

confidence: 83%

“…The genus Lindera (Family: Lauraceae) consists of about 100 species widely distributed in tropical, subtropical, and temperate zones of Asia and Midwestern America [1]. Various species of Lindera plants are used in traditional medicine for the treatment of different ailments including rheumatoid arthritis, stroke, cholera, diarrhea, toothache, and nausea [1][2][3]. Lindera plants are a rich source of fatty and essential oils that are used for the production of soaps, lubricants, spices, fragrances, and timber [1].…”

Section: Introductionmentioning

confidence: 99%

“…Various species of Lindera plants are used in traditional medicine for the treatment of different ailments including rheumatoid arthritis, stroke, cholera, diarrhea, toothache, and nausea [1][2][3]. Lindera plants are a rich source of fatty and essential oils that are used for the production of soaps, lubricants, spices, fragrances, and timber [1]. Different types of secondary metabolites have reportedly been isolated from Lindera plants including sesquiterpenoids, alkaloids, butanolides, lucidones, phenylpropanoids, isocoumarins, and lignans [1,[4][5][6].…”

Section: Introductionmentioning

confidence: 99%

“…Lindera plants are a rich source of fatty and essential oils that are used for the production of soaps, lubricants, spices, fragrances, and timber [1]. Different types of secondary metabolites have reportedly been isolated from Lindera plants including sesquiterpenoids, alkaloids, butanolides, lucidones, phenylpropanoids, isocoumarins, and lignans [1,[4][5][6]. Flavonoids have also reportedly been isolated from several Lindera plants including Lindera umbellata, Lindera lucida, Lindera erythrocarpa, Lindera aggregata, and Lindera obtusiloba [7,8].…”

Section: Introductionmentioning

confidence: 99%

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Extraction and Isolation of Kaempferol Glycosides from the Leaves and Twigs of Lindera neesiana

et al. 2019

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The hydroalcoholic extract of leaves and twigs of Lindera neesiana (Wall. ex Nees) Kurz (Lauraceae) was subjected to various column chromatographic methods that isolated five kaempferol glycosides: kaempferol 3-O-β-glucopyranosyl(1→2)-[α-rhamnopyranosyl-(1→6)]-β- glucopyranoside-7-O-α-rhamnopyranoside (1); kaempferol 3-O-β-glucopyranosyl-(1→2)-[α-rhamnopyranosyl (1→6)]-β-glucopyranoside (2); kaempferol 3-O-β-glucopyranosyl(1→2)- α-rhamnopyranoside-7-O-α-rhamnopyranoside (3); kaempferol 3-O-sophoroside (4); and kaempferol 3-O-α-rhamnopyranoside (5). The extract showed moderate free radical scavenging activity and potent pancreatic lipase inhibitory activity.

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Section: Resultsmentioning

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Extraction and Isolation of Kaempferol Glycosides from the Leaves and Twigs of Lindera neesiana

et al. 2019

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“…Lindera megaphylla; Illumina sequence; chloroplast genome; phylogenetic position Lindera (Lauraceae) is a genus of flowering plants including nearly 100 species distributed in tropical and subtropical Asia and North American (Cao et al 2016). About 40 species of Lindera distributed widely in China indicated high species diversity in this region.…”

mentioning

confidence: 99%

Characterization of two complete chloroplast genomes of Lindera megaphylla (Lauraceae)

Jiang

Wang

Huang

et al. 2019

Mitochondrial DNA Part B

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Lindera megaphylla (Lauraceae) is an ecologically important and dominant evergreen broad-leaf tree species in the warm-temperate and subtropical zone of China. In this study, we sequenced and assembled two complete genomes of L. megaphylla (LM01 and LM02) based on the next-generation sequencing data. The two complete chloroplasts of L. megaphylla are 152,741 bp in length, including two same length inverted repeats of 20,067 and 20,068 bp, a small single copy of 18,882 and 18,914 bp and a large single copy of 93,726 and 93,691 bp for LM01 and LM02 respectively. They all contain 84 protein-coding, 36 tRNA and eight rRNA genes. The phylogenetic analysis based on chloroplast genomes indicates that L. megaphylla is closely related to another Lindera and Litsea species.

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Essential Oils of the Leaves of Epaltes australis Less. and Lindera myrrha (Lour.) Merr.: Chemical Composition, Antimicrobial, Anti‐inflammatory, Tyrosinase Inhibitory, and Molecular Docking Studies

Pham,

Huu Cuong,

Hong Ha

et al. 2023

Chemistry & Biodiversity

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The chemical compositions of essential oils from the leaves of Epaltes australis and Lindera myrrha, and their biological potentials are first reported in this research. Essential oils obtained by hydro‐distillation were analyzed by GC‐MS. Non‐terpenic compounds (46.3%) achieved the highest amount in E. australis, and thymohydroquinone dimethyl ether was the major compound with the highest percentage of 44.2%. Sesquiterpene hydrocarbons (56.8%) prevailed in L. myrrha leaf oil, and the principal compounds were (E)‐caryophyllene (22.2%), ledene (9.7%), selina‐1,3,7(11)‐trien‐8‐one (9.6%), and α‐pinene (7.0%). Both essential oils exhibited antimicrobial activity against the bacteria Bacillus subtilis and Clostridium sporogenes, and Escherichia coli, and the fungus Aspergillus brasiliensis. L. myrrha leaf essential oil strongly controlled the yeast Saccharomyces cerevisiae with a MIC of 32 µg/mL. L. myrrha leaf oil (IC50 15.20 µg/mL) also showed strong anti‐inflammatory activity against NO production in LPS‐stimulated RAW2647 murine macrophage cells. In anti‐tyrosinase activity, E. australis leaf oil showed the best monophenolase inhibition with the IC50 of 245.59 µg/mL, while L. myrrha leaf oil inhibited diphenolase with the IC50 of 152.88 µg/mL. From docking study, selina‐1,3,7(11)‐trien‐8‐one showed the highest affinity for both COX‐2 and TNF‐α receptors. Hydrophobic interactions play a great role in the bindings of the studied ligand‐receptor complexes.

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The genus Lindera: a source of structurally diverse molecules having pharmacological significance

Cited by 49 publications

References 134 publications

Extraction and Isolation of Kaempferol Glycosides from the Leaves and Twigs of Lindera neesiana

Extraction and Isolation of Kaempferol Glycosides from the Leaves and Twigs of Lindera neesiana

Characterization of two complete chloroplast genomes of Lindera megaphylla (Lauraceae)

Essential Oils of the Leaves of Epaltes australis Less. and Lindera myrrha (Lour.) Merr.: Chemical Composition, Antimicrobial, Anti‐inflammatory, Tyrosinase Inhibitory, and Molecular Docking Studies

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