The genus Uncinocarpus (Onygenaceae) and its synonym Brunneospora: new concepts, combinations and connections to anamorphs in Chrysosporium, and further evidence of relationship with Coccidioides immitis

Sigler, Lynne; Flis, Arlene L.; Carmichael, J. W.

doi:10.1139/b98-110

Cited by 29 publications

(34 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Aleurioconidia were club shaped to broadly obovoid (egg shaped), were slightly warty, and measured 5 to 7 m long and 3 to 4 m wide; arthroconidia measured 7 to 11 m long and 2 to 3 m wide. The identification was confirmed by mating the case isolate with reference strains of Uncinocarpus orissi, which was identified previously as the teleomorph of C. zonatum (12). It was determined as a plus mating type based on its formation of ascomata and ascospores when paired with a minus mating type strain (UAMH 8936).…”

Section: Case Reportmentioning

confidence: 89%

“…C. zonatum is recognized by its fast growth at 37°C and by colonies that darken to buff. First described in 1989 in Kuwait, this species is now known to occur in North America, Europe, Asia, and the Middle East (12). Mating studies revealed that the species is the anamorph of an ascomycete that has been named U. orissi (Onygenaceae) (12); however, the placement of the teleomorph in the genus Uncinocarpus was disputed in a later study (14).…”

Section: Case Reportmentioning

confidence: 99%

“…First described in 1989 in Kuwait, this species is now known to occur in North America, Europe, Asia, and the Middle East (12). Mating studies revealed that the species is the anamorph of an ascomycete that has been named U. orissi (Onygenaceae) (12); however, the placement of the teleomorph in the genus Uncinocarpus was disputed in a later study (14). Further investigation is needed to clarify the relationship between U. orissi and U. reesii, the type species of the genus Uncinocarpus.…”

Section: Case Reportmentioning

confidence: 99%

See 2 more Smart Citations

Pulmonary Colonization by Chrysosporium zonatum Associated with Allergic Inflammation in an Immunocompetent Subject

et al. 2002

Self Cite

View full text Add to dashboard Cite

We report a case of noninvasive pulmonary disease due to Chrysosporium zonatum in an immunocompetent male. The fungus colonized an existing tuberculous cavity and was isolated from transbronchial lavage fluid and from a percutaneous aspiration specimen. The disease was accompanied by the unusual feature of an allergic reaction. The fungus ball was successfully treated by intracavitary administration of amphotericin B. C. zonatum is the anamorph of the heterothallic ascomycete Uncinocarpus orissi, and the identity of the case isolate was verified by formation of ascospores in mating tests with reference isolates. CASE REPORTA 72-year-old man initially visited another hospital complaining of a productive cough and fever in December of 1995. He had experienced pulmonary tuberculosis 10 years earlier.Previous chest X-rays revealed thin wall cavities in the right upper lobe (RUL), but otherwise he was in good health. Changes in the chest X-rays, i.e., thickened cavity walls with airspace consolidation in the RUL, suggested the presence of a bacterial infection. However, bacteriological cultures of blood and sputum specimens were negative. The patient failed to respond to empirical antibiotic therapy with clindamycin and imipenem and developed dyspnea. At admission to Saga Medical School Hospital on 25 January 1996, chest X-rays and computed tomography (CT) revealed enlarged cavities, in one of which an air-fluid level was noted, in the RUL. Bilateral mixed airspace and interstitial infiltrations, distributed mainly in the right lower lobe (RLL), were also observed. An increase in eosinophils was noted in peripheral blood (around 900/l) and in bronchoalveolar lavage (BAL) fluid from the RLL (14%). Histopathological examination of transbronchial lung specimens from the RLL indicated interstitial infiltration of numerous lymphoplasmacytoid cells and smaller numbers of neutrophils and eosinophils. No organisms were detected by periodic acid-Schiff and Ziehl-Neelsen staining. As his clinical symptoms and pulmonary infiltrations worsened, peripheral eosinophils were elevated to 2,600/l, suggesting involvement of an allergic process. Corticosteroid therapy was started on 20 February. Consequently, the symptoms subsided and the diffuse infiltrations and air-fluid level in the cavity diminished. A follow-up CT scan revealed a homogeneous round mass suggestive of a fungus ball in one of the cavities (Fig. 1). While receiving oral prednisolone at 10 mg/day, the patient developed a mild fever and an intermittent productive cough. Because the clinical course resembled allergic bronchopulmonary aspergillosis, oral itraconazole (ITRA), 100 mg/day, was added on 22 March.Specimens were collected by BAL on 19 March and CTguided percutaneous needle aspiration on 10 April and sent for microbiological analysis. Microscopic observations of gramand Giemsa-stained specimens were negative for hyphae. The samples were cultured on sheep blood agar at 35°C for 2 days and Sabouraud dextrose agar (Difco Laboratories, Detroit, Mich.) at 30°C for 7...

show abstract

Section: Case Reportmentioning

confidence: 89%

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

See 1 more Smart Citation

Pulmonary Colonization by Chrysosporium zonatum Associated with Allergic Inflammation in an Immunocompetent Subject

et al. 2002

Self Cite

View full text Add to dashboard Cite

show abstract

“…Their closest relative for which a genome sequence is currently published, determined by both phylogenetic analysis and morphology, is Uncinocarpus reesii (Onygenaceae), a keratinophilic saprotroph (6,7). Whereas U. reesii has a known sexual life cycle (7,8), the sexual cycle of Coccidioides remains undescribed. No other dimorphic pathogens of humans have been described in the Onygenaceae family (7,9,10).…”

Section: Mycology and Population Structurementioning

confidence: 99%

“…Whereas U. reesii has a known sexual life cycle (7,8), the sexual cycle of Coccidioides remains undescribed. No other dimorphic pathogens of humans have been described in the Onygenaceae family (7,9,10). The Onygenales order, however, contains other dimorphic pathogens, such as Paracoccidioides brasiliensis, Ajellomyces (Histoplasma) capsulatus, and Ajellomyces (Blastomyces) dermatitidis (10,11).…”

Section: Mycology and Population Structurementioning

confidence: 99%

Recent Advances in Our Understanding of the Environmental, Epidemiological, Immunological, and Clinical Dimensions of Coccidioidomycosis

et al. 2013

View full text Add to dashboard Cite

SUMMARY Coccidioidomycosis is the endemic mycosis caused by the fungal pathogens Coccidioides immitis and C. posadasii . This review is a summary of the recent advances that have been made in the understanding of this pathogen, including its mycology, genetics, and niche in the environment. Updates on the epidemiology of the organism emphasize that it is a continuing, significant problem in areas of endemicity. For a variety of reasons, the number of reported coccidioidal infections has increased dramatically over the past decade. While continual improvements in the fields of organ transplantation and management of autoimmune disorders and patients with HIV have led to dilemmas with concurrent infection with coccidioidomycosis, they have also led to advances in the understanding of the human immune response to infection. There have been some advances in therapeutics with the increased use of newer azoles. Lastly, there is an overview of the ongoing search for a preventative vaccine.

show abstract

Coccidioidomycosis in Animals

Barker

2018

Emerging and Epizootic Fungal Infections in Animals

View full text Add to dashboard Cite

The genus Uncinocarpus (Onygenaceae) and its synonym Brunneospora: new concepts, combinations and connections to anamorphs in Chrysosporium, and further evidence of relationship with Coccidioides immitis

Cited by 29 publications

References 19 publications

Pulmonary Colonization by Chrysosporium zonatum Associated with Allergic Inflammation in an Immunocompetent Subject

Pulmonary Colonization by Chrysosporium zonatum Associated with Allergic Inflammation in an Immunocompetent Subject

Recent Advances in Our Understanding of the Environmental, Epidemiological, Immunological, and Clinical Dimensions of Coccidioidomycosis

Coccidioidomycosis in Animals

Contact Info

Product

Resources

About