The genus <i>Artemisia</i> L. in the northern region of Saudi Arabia: essential oil variability and antibacterial activities

Guetat, Arbi; Al-Ghamdi, Faraj A.; Osman, Ahmed K.

doi:10.1080/14786419.2016.1207071

Cited by 45 publications

(16 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…38 The antimicrobial significance of EOs might be correlated with the presence of free hydroxyl groups in terpenoid compounds that play a significant role as antimicrobial and antioxidant agents. 17,18,25,26 Our results demonstrate that the EOs of the four Artemisia plants include high concentrations of terpenoids with free hydroxyl groups, such as yomogi alcohol (22.4%), artemesia alcohol (9.91%), 1,8-cineole (9.68%), and endo-borneol (5.72%).…”

Section: Antimicrobial Activitymentioning

confidence: 78%

“…Artemisia monosperma is widespread in desert plains and wadis, and its leaves are widely used in Egypt and Saudi Arabia in folk medicine . It demonstrates antibacterial activity against Streptococcus agalactiae with a stronger inhibition than recorded for ampicillin …”

Section: Introductionmentioning

confidence: 99%

“…2 It demonstrates antibacterial activity against Streptococcus agalactiae with a stronger inhibition than recorded for ampicillin. 17 Essential oils and their components have many applications in folk medicine, food flavouring, preservation, and in cosmetic and pharmaceutical industries. 18 The spread of drug-resistant microbial pathogens is one of the most serious threats to the successful treatment of infectious diseases.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Comparative chemical study and antimicrobial activity of essential oils of three Artemisia species from Egypt and Saudi Arabia

Amin

Hassan

Gendy

et al. 2019

Flavour & Fragrance J

View full text Add to dashboard Cite

The chemical composition of essential oils (EOs) distilled from three wild Artemisia species, Artemisia herba‐alba, Artemisia judaica, and Artemisia monosperma, collected from Egypt, and Saudi Arabia, were analysed by gas chromatography–mass spectrometry (GC‐MS). The antibacterial activities of the EOs for all species were determined using the Agar disc diffusion method. The yield of the EOs ranged from 0.16 to 0.49%. The results showed that A. monosperma plants growing in Saudi Arabia gave the highest yield, compared with A. herba‐alba, A. judaica, and A. monosperma collected from Egypt. In total, 92 volatile compounds were identified from the aerial parts of the plants using GC‐MS. Oxygenated monoterpenes were the major class in A. herba‐alba (75.31%) and A. judaica (83.07%), whereas monoterpene hydrocarbons were the major representative group in A. monosperma collected from both Saudi Arabia (34.23%) and Egypt (36.23%). Yomogi alcohol (22.4%), artemesia alcohol (9.91%), and 1,8‐cineole (9.68%) were the major components of the EO of A. herba‐alba, whereas camphor (31.4%), piperitone (29.9%), and endo‐borneol (5.72%) were characterized as the main compounds in A. judaica. β‐Vinylnaphthalene (24.89%), β‐eudesmol (15.41%), and β‐pinene (20.67%) represented the main components of the EO of Saudi Arabian A. monosperma, but β‐pinene (11.89%), (–)‐spathulenol (8.84%), p‐cymene (8.83%), and shyobunone (7.05%) were the major components of the EO of Egyptian A. monosperma. Herein, a comparative analysis between the EOs of Egyptian Artemisia and those collected from Saudi Arabia was performed with principal components analysis (PCA) and agglomerative hierarchical clustering (AHC). The minimum inhibitory concentration (MIC) values ranged from 0.5 to2.5 μL per disc against different microorganisms. Artemisia judaica and A. monosperma (Saudi Arabia) plants had the highest MICs and A. monosperma (Egypt) had the lowest MIC, which may indicate different compositions as a result of climatic variation.

show abstract

Section: Antimicrobial Activitymentioning

confidence: 78%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Comparative chemical study and antimicrobial activity of essential oils of three Artemisia species from Egypt and Saudi Arabia

Amin

Hassan

Gendy

et al. 2019

Flavour & Fragrance J

View full text Add to dashboard Cite

show abstract

“…1 Different extracts of A. monosperma exhibited a wide spectrum of biological actions such as muscle relaxation, [6][7][8] antidiabetic, 1,8 and antimicrobial activities. [9][10][11][12][13][14] Bioactive compounds isolated from Artemisia species showed antispasmodic, 15,16 antihypertensive, 17 antimicrobial, 12,13 insect repellents, [18][19][20] antitumor and anti-inflammatory activities. [21][22][23] Arcapillin was first identified from A. capillaris 24 and it was reported an antihepatotoxic.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Antispasmodic Effect of Arcapillin on Smooth Muscles of Rats

Abu-Niaaj¹,

Katampe²,

Abdalla³

2019

View full text Add to dashboard Cite

Background: Arcapillin, 2',4',5-trihydroxy-5',6,7-trimethoxyflavone, is a flavone aglycone isolated from several Artemisia species, though, it was first identified from A. capillaris. The Artemisia species are used in folk medicine as a remedy for gastrointestinal and liver illnesses, hypertension, fever and inflammation. Studies indicated a potential role of arcapillin to relieve symptoms of liver disorders; however, there is no report yet in the literature of its effect on smooth muscles. Objective: Our study aims to evaluate the effect of arcapillin, isolated from A. monosperma, on the contractile activity of rat smooth muscles. Materials and Methods: Increased concentrations of arcapillin were tested on isolated rat ileum, pulmonary artery, trachea, and urinary bladder. The muscle contraction was recorded upon addition of arcapillin in eight cumulative concentrations of half log units in the range of [10-7 M-3×10-4 M]. Depending on the organ-containing muscles, the preparations were treated with arcapillin either at basal tonus or after pre-stimulated via a contractile agent; 10-3 M O-acetylcholine on ileum and 10-5 M L-phenylephrine on pulmonary artery rings. Control tissues were treated with sodium hydroxide in an equivalent concentration to that used to dissolve the flavone. Results: Arcapillin caused a dose-dependent relaxation on ileum preparation and pulmonary artery. The inhibition of the contractile activity of ileum was reversible within 60 seconds after washing off the flavone. The urinary bladder showed a slight increase in contraction at the highest concentrations starting at [10-4 M] of arcapillin. There was no observed effect on the contraction of tracheal smooth muscles by all tested concentrations of arcapillin. Conclusion: The antispasmodic activity of arcapillin may contribute to the pharmaceutical importance of A. monosperma in particularly to treat gastrointestinal disorders.

show abstract

“…O gênero Artemísia (Artemísia spp.) apresenta uma história terapêutica há mais de dois mil anos, sendo amplamente utilizada na medicina popular, além de ser um dos gêneros mais estudados devido a sua diversidade morfológica, química e biológica [3].As espécies que fazem parte do gênero Artemisia spp., compreendem, na verdade, importantes plantas medicinais que atualmente são objeto de atenção fitoquímica devido à sua produção grande produção de metabólitos secundários, diversidade química e biológica [4]. As espécies do gênero Artemisa spp., apresentam uma gama de atividades biológicas, como no caso da espécie Artemisia annua, que possui polissacarídeos com atividade antitumoral e dotada de propriedades imunomoduladoras [5].…”

Section: Article Id Introduçãounclassified

Avaliação do extrato bruto de Artemisia vulgaris na resposta imunológica

Zamarioli¹,

Santos²,

Marcucci³

et al. 2019

Braz. J. Nat. Sci

View full text Add to dashboard Cite

A Artemisia vulgaris é uma das espécies do gênero Artemisia, gênero o qual possui grande história terapêutica e estudos. Suas partes aéreas são tradicionalmente consumidas pela população sob forma de infusão (chá), por acreditar que possui propriedades anti-helmíntica, antisséptica, antiespasmódica, anti-inflamatória e, até mesmo, como tônico para órgãos vitais. Este trabalho, teve como objetivo avaliar o extrato bruto (EB) da Artemisia vulgaris na resposta imunológica, com base na história terapêutica da planta e na etnofarmacologia . Para o desenvolvimento, foram utilizadas técnicas para obtenção e análise dos compostos do extrato por cromatografia líquida de alta eficiência (HPLC), sendo identificados como os principais compostos a artemisinina, e os ácidos clorogênico e cafeoilquínico. Posteriormente foi realizado o tratamento da linhagem celular RAW (macrófagos murinos) com o EB. As células foram tratadas com diferentes concentrações de extrato (de 0,25% a 2%), por um período de 24 horas, e estimuladas com lipopolissacarídio (LPS) bacteriano, com o intuito de se observar a produção de citocinas. Após a segunda incubação por 24 horas, o sobrenadante dessa linhagem foi recolhido, e a análise da produção de citocinas pró-inflamatórias, interleucina (IL)-6 e anti-inflamatórias, IL-4, foi feita por imunoensaio (teste de ELISA), avaliando, assim, a influência do extrato de A.vulgaris na resposta imunológica.

show abstract

The genus Artemisia L. in the northern region of Saudi Arabia: essential oil variability and antibacterial activities

Cited by 45 publications

References 22 publications

Comparative chemical study and antimicrobial activity of essential oils of three Artemisia species from Egypt and Saudi Arabia

Comparative chemical study and antimicrobial activity of essential oils of three Artemisia species from Egypt and Saudi Arabia

Evaluation of Antispasmodic Effect of Arcapillin on Smooth Muscles of Rats

Avaliação do extrato bruto de Artemisia vulgaris na resposta imunológica

Contact Info

Product

Resources

About