THE GASTRIC LESION IN PERNICIOUS ANqMIA

Magnus, Hugo

doi:10.1016/s0140-6736(00)86180-2

Cited by 98 publications

(10 citation statements)

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“…Sparing of the antral mucosa in atrophic gastritis associated with pernicious anaemia was originally found in necropsy studies by Magnus and Ungley (1938). te Velde et al (1966) showed that histological appearances of the fundus in chronic gastritis associated with parietal cell antibody differ morphologically from those seen in chronic gastritis without gastric autoantibodies.…”

Section: Discussionmentioning

confidence: 95%

Serum Gastrin and the Antral Mucosa in Atrophic Gastritis

Strickland¹,

Bhathal²,

Korman³

et al. 1971

BMJ

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seronegative for parietal cell antibody) had either a normal antrum or minimal (grade 1) antral gastritis. In contrast all but one patient without raised serum gastrin (nine seronegative and two seropositive for parietal cell antibody) had severe (grades 2-3) antral gastritis. Thus circulating gastrin levels observed in patients with gastritis and achlorhydria can be directly related to the presence or absence of antral mucosal damage.Comparison of the histological appearances of the antral mucosa with serum gastrin and parietal cell antibody status has provided a basis for the separation of two distinctive forms of atrophic gastritis.

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Section: Discussionmentioning

confidence: 95%

Serum Gastrin and the Antral Mucosa in Atrophic Gastritis

Strickland¹,

Bhathal²,

Korman³

et al. 1971

BMJ

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“…The lam ina propria of the fundic and corpus mucosa is infiltrated with mononuclear cells [11]. There is no involvement of the antrum.…”

Section: Type Of Chronic Atrophic Gastritismentioning

confidence: 99%

The Gastrointestinal Tract in Pernicious Anemia

Loffeld

Spreeuwel²

1991

Dig Dis

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“…It was not productive of delay, and is not menticned by Jacobson and Palmer (1943) in a radiological study of gastric emptying in pernicious anaemia. The lower stomach is not usually abnormal in perniciou.s anaemia (Magnus and Ungley, 1938), and gastroscopy confirms this. An abnormal antral mucosa, especially when associated with a narrow antral canal, may predispose to malignancy.…”

Section: Discussionmentioning

confidence: 54%

Cancer of the Stomach in Addison's Anaemia

Bourne¹

1948

BMJ

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THE GASTRIC LESION IN PERNICIOUS ANqMIA

Cited by 98 publications

References 0 publications

Serum Gastrin and the Antral Mucosa in Atrophic Gastritis

Serum Gastrin and the Antral Mucosa in Atrophic Gastritis

The Gastrointestinal Tract in Pernicious Anemia

Cancer of the Stomach in Addison's Anaemia

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