The future of research in genitourinary radiology: through the looking glass--a view from the Society of Uroradiology.

Choyke, Peter L.; Hricak, H.; Kenney, Philip J.; Cm, Sandler; Bush, William H.; Clark, Roderick

doi:10.1148/radiology.207.1.9530290

Cited by 9 publications

(3 citation statements)

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“…RCCs are poorly responsive to radiotherapy or chemotherapy; although interferon-a improves the survival of patients with metastatic RCC by a median of 2.5 months, this improvement needs to be balanced against the toxic effects of this drug [5]. Other alternatives to radical nephrectomy include nephron-sparing surgery, including tumour enucleation [6], laparoscopic nephrectomy [7,8] embolization with alcohol or other embolic material [9][10][11][12], percutaneous or laparoscopic cryotherapy [13], focused ultrasound (FUS) [14], radiofrequency ablation (RFA) [15,16], and cystoscopic or percutaneous laser thermal ablation (LTA) [17].…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging‐guided laser thermal ablation of renal tumours

Dick¹,

Joarder²,

Jode³

et al. 2002

BJU International

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Objective To test the hypothesis that magnetic resonance imaging (MRI)-guided laser thermal ablation (LTA) of inoperable renal tumours is a safe, tolerable and potentially effective treatment . Patients and methods Nine patients (aged 56-81 years) with malignant renal tumours underwent percutaneous LTA under MRI guidance in a 0.5 T open magnet. Real-time colour thermal mapping was used to monitor tumour ablation, and the follow-up was with gadolinium-enhanced MRI at 6 weeks and (where appropriate) 3-4 months after the procedure. Tumour volume and percentage tumour enhancement before and after ablation were compared . The percentage of tumour ablated on real-time T1-weighted thermal maps was compared with that on gadoliniumenhanced follow-up MRI . Results The mean (range) follow-up was 16.9 (3-32) months after the first ablation. The mean tumour size did not change significantly, but the mean percentage of viable tumour decreased significantly from 73.7% before to 29.5% after ablation ( P = 0.012, Wilcoxon signed-ranks test). Thermal maps correlated moderately well with follow-up MRI in predicting the extent of tumour ablation (Pearson correlation coefficient 0.55). There were two minor and one major complication. Conclusion In this pilot study of patients unsuitable for surgery, MRI-guided LTA of renal tumours was safe, feasible (being well tolerated by the patient) and significantly reduced enhancing tumour volume by a mean of 45%.

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Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging‐guided laser thermal ablation of renal tumours

Dick¹,

Joarder²,

Jode³

et al. 2002

BJU International

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“…Along with the increasing potential for early diagnosis has been the burgeoning development of minimally invasive, imaging-guided procedures, and an increasing role for percutaneous interventional radiologic therapies has been suggested for the treatment of small RCCs [6]. Tissue ablation in the kidneys has been described using techniques such as cryo- …”

Section: Discussionmentioning

confidence: 99%

MR-guided RF thermal ablation of the kidney in a porcine model.

Merkle

Shonk

Duerk³

et al. 1999

American Journal of Roentgenology

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“…In the past decade several authors have discussed the role of the IVU after appearance of the cross-sectionalimaging techniques [4,5,6,7,8,9,10,11,12].…”

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confidence: 99%

What is left of i.v. urography?

Palma

2001

Eur Radiol

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Since its introduction into clinical practice in the early 1930s, intravenous urography (IVU) was the primary imaging technique for the investigation of urinary system disorders for many years, until the advent of digital cross-sectional-imaging techniques gradually started to undermine many of its indications. Intravenous urography has been superseded for some indications such as renovascular arterial hypertension, prostatic dysuria, renal failure, palpable abdominal masses and recurrent urinary tract infection in women. Intravenous urography has been reduced, in the sense that it is no longer a primary examination, for other clinical indications such as renal colic, renal trauma, uroseptic fever, asymptomatic haematuria, medical haematuria, obstructive uropathies and follow-up of various disorders. Intravenous urography is indicated and often mandatory in congenital anomalies of the urinary tract, prior to endourological procedures, possible fistulas, renal transplantation, tuberculosis and ureteral pathology. In conclusion, IVU is still the examination of choice where there is a need to visualize the entire urinary system and to evaluate the state of the papillae and calyces. Computed tomography urography and MR urography are the imaging modalities ready in the near future to replace IVU.

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The future of research in genitourinary radiology: through the looking glass--a view from the Society of Uroradiology.

Cited by 9 publications

References 0 publications

Magnetic resonance imaging‐guided laser thermal ablation of renal tumours

Magnetic resonance imaging‐guided laser thermal ablation of renal tumours

MR-guided RF thermal ablation of the kidney in a porcine model.

What is left of i.v. urography?

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