The fungal leaf endophyte Paraconiothyrium variabile specifically metabolizes the host-plant metabolome for its own benefit

Tian, Yuan; Amand, Séverine; Buisson, Didier; Kunz, Caroline; Hachette, François; Dupont, Joëlle; Nay, Bastien; Prado, Soizic

doi:10.1016/j.phytochem.2014.09.021

Cited by 63 publications

(42 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In all cases, this led to the production of the corresponding aglycone in the medicinal host plant Cephalotaxus harringtonia via deglycosylation. The deglycosylated flavonoids turned out to display significant beneficial effects on the hyphal growth of germinated spores (Tian et al 2014). These data proved that a close interaction between the two organisms took place on a biochemical level.…”

Section: Metabolism Of Plant Host Compounds By Endophytesmentioning

confidence: 61%

“…Therefore, the changes in the metabolome were monitored and these compounds, where the main changes were observed, were tested for beneficial effects on the fungus. A specific biotransformation of glycosylated flavonoids by the endophyte was observed (Tian et al 2014) (Fig. 2).…”

Section: Metabolism Of Plant Host Compounds By Endophytesmentioning

confidence: 93%

“…The fungal leaf endophyte, Paraconiothyrium variabile, is able to metabolize its host plant metabolome (Tian et al 2014). However, the function of these biochemical reactions is not yet well understood.…”

Section: Metabolism Of Plant Host Compounds By Endophytesmentioning

confidence: 99%

See 2 more Smart Citations

Plants and endophytes: equal partners in secondary metabolite production?

2015

View full text Add to dashboard Cite

Well known plant production systems should be re-evaluated due to findings that the interesting metabolite might actually be produced by microbes intimately associated with the plant, so-called endophytes. Endophytes can be bacteria or fungi and they are characterized usually by the feature that they do not cause any harm to the host. Indeed, in some cases, such as mycorrhizal fungi or other growth promoting endophytes, they can be beneficial for the plant. Here some examples are reviewed where the host plant and/or endophyte metabolism can be induced by the other partner. Also, partial or complete biosynthesis pathways for plant secondary metabolites can be attributed to such endophytes. In other cases the host plant is able to metabolize substances from fungal origin. The question of the natural role of such metabolic changes for the endophyte will be briefly touched. Finally, the consequences for the use of plant cultures for secondary metabolite production is discussed.

show abstract

Section: Metabolism Of Plant Host Compounds By Endophytesmentioning

confidence: 61%

Section: Metabolism Of Plant Host Compounds By Endophytesmentioning

confidence: 93%

See 1 more Smart Citation

Plants and endophytes: equal partners in secondary metabolite production?

2015

View full text Add to dashboard Cite

show abstract

“…, have been detected as transformation products by a strain of Paraconiothyrium variabile endophytic in the Japanese plum yew (Cephalotaxus harringtonii) growing on crude extracts of the same plant, by which these compounds had been previously reported [146].…”

Section: Flavonoidsmentioning

confidence: 76%

Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta

2015

View full text Add to dashboard Cite

Abstract:It is known that plant-based ethnomedicine represented the foundation of modern pharmacology and that many pharmaceuticals are derived from compounds occurring in plant extracts. This track still stimulates a worldwide investigational activity aimed at identifying novel bioactive products of plant origin. However, the discovery that endophytic fungi are able to produce many plant-derived drugs has disclosed new horizons for their availability and production on a large scale by the pharmaceutical industry. In fact, following the path traced by the blockbuster drug taxol, an increasing number of valuable compounds originally characterized as secondary metabolites of plant species belonging to the Spermatophyta have been reported as fermentation products of endophytic fungal strains. Aspects concerning sources and bioactive properties of these compounds are reviewed in this paper.

show abstract

“…In addition to the importance of local site parameters in shaping needle mycobiomes, various studies have confirmed a strong interplay of phyllosphere fungi with their host plants and significant correlations with phenotypic and physiological plant traits (Kembel & Mueller, ; Rajala et al ., ; Tian et al ., ). Similarly, our analyses revealed a significant correlation of fungal communities with the combined phenotypic differences of the trees and with tree age and height as strong single determinants.…”

Section: Discussionmentioning

confidence: 97%

Habitat conditions and phenological tree traits overrule the influence of tree genotype in the needle mycobiome–Picea glauca system at an arctic treeline ecotone

et al. 2016

View full text Add to dashboard Cite

SummaryPlant-associated mycobiomes in extreme habitats are understudied and poorly understood. We analysed Illumina-generated ITS1 sequences from the needle mycobiome of white spruce (Picea glauca) at the northern treeline in Alaska (USA). Sequences were obtained from the same DNA that was used for tree genotyping. In the present study, fungal metabarcoding and tree microsatellite data were compared for the first time.In general, neighbouring trees shared more fungal taxa with each other than trees growing in further distance. Mycobiomes correlated strongly with phenological host traits and local habitat characteristics contrasting a dense forest stand with an open treeline site. Genetic similarity between trees did not influence fungal composition and no significant correlation existed between needle mycobiome and tree genotype.Our results suggest the pronounced influence of local habitat conditions and phenotypic tree traits on needle-inhabiting fungi. By contrast, the tree genetic identity cannot be benchmarked as a dominant driver for needle-inhabiting mycobiomes, at least not for white spruce in this extreme environment.

show abstract

The fungal leaf endophyte Paraconiothyrium variabile specifically metabolizes the host-plant metabolome for its own benefit

Cited by 63 publications

References 40 publications

Plants and endophytes: equal partners in secondary metabolite production?

Plants and endophytes: equal partners in secondary metabolite production?

Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta

Habitat conditions and phenological tree traits overrule the influence of tree genotype in the needle mycobiome–Picea glauca system at an arctic treeline ecotone

Contact Info

Product

Resources

About