The fundamentals and applications of piezoelectric materials for tumor therapy: recent advances and outlook

Abstract

The malignant tumor is one of the mainly diseases leading to death, and the vigorous development of nanotechnology has opened up new frontiers for antitumor therapy. The process of researchers...

Significantly Enhanced Poling Efficiency of Piezocomposites by Tuning Resistivity of a Polymer Matrix

“…Figure e,f presents the tensile properties of the pure PDMS, BCZT/PDMS, and BCZT/1.0Cu-PDMS samples. Because of the small addition of Cu NWs, the BCZT/1.0Cu-PDMS sample had a small Young’s modulus of 2.92 MPa, which was only slightly larger than that of the BCZT/PDMS sample and very close to that of human skin. , Moreover, the elongation at break of the BCZT/1.0Cu-PDMS sample was still above 110% (Figure f), which demonstrates its great potential in the field of biointegrated electronics. , …”

“…51,52 Moreover, the elongation at break of the BCZT/ 1.0Cu-PDMS sample was still above 110% (Figure 4f), which demonstrates its great potential in the field of biointegrated electronics. 53,54 To evaluate the insulation characteristics of the PDMS matrix modified with Cu NWs, yCu-PDMS samples were prepared. Figure 5a shows the DC resistivity of the yCu-PDMS samples.…”

Bio-piezoelectric phenylalanine-αβ-dehydrophenylalanine nanotubes as potential modalities for combinatorial electrochemotherapy in glioma cells

“…48,49 Acoustic stimuli have been reportedly applied in the brain for treating various neuropathological conditions including glioma and Alzheimer's. 50 Marino et al utilized chronic US signals at 1 MHz frequency and at an intensity of 1 W cm −2 in cells for inducing an anticancer effect in temozolomide loaded piezoelectric barium titanate NPs. 51 Another group of researchers explored the potential of nutlin-3a-loaded ApoE-functionalized P(VDF-TrFE) NPs for achieving a combined chemo-piezo therapeutic effect on T98G glioma cells.…”

Reactive oxygen species for therapeutic application: Role of piezoelectric materials

“…81 They possess higher catalytic activity for increased surface area, promising electron transfer, easy penetration to cell membranes or blood channels and effortlessness in transportation which effectuate the drug delivery. 6,82…”