THE FUNCTIONAL CHARACTER OF Auricularia auricula CRUDE POLYSACCHARIDES: ANTIOXIDANT AND  ANTIBACTERIAL ACTIVITY

Elfirta, Rizki Rabeca; Saskiawan, Iwan

doi:10.14203/beritabiologi.v19i3b.3988

Cited by 6 publications

(5 citation statements)

References 26 publications

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“…This is probably related to the capability of antibiotic resistance of S. aureus bacteria. These bacteria have been reported to overgrow and succeed because they produce the enzyme coagulase associated with pathogenicity in these bacteria (Elfirta and Saskiawan, 2020). Pathogenicity is affected by coagulase action, which can coagulate and accumulate fibrin across the bacteria, making it difficult for antibiotics to reach the bacterial cell wall (Kumar et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Bioprospection of Enggano Macroscopic Fungi as Antibacterial and Antioxidant Agents

et al. 2021

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Macrofungi in Indonesia have not been widely studied for their pharmacological activity, especially as a source of antibacterial and antioxidant properties, even though Indonesia as a tropical country has quite a high diversity of macrofungi. This study aims to reveal the potential of macrofungi from the Enggano forest as a source of antibacterial and antioxidant compounds. Four types of macrofungi were collected and their metabolites were extracted using four types of organic solvents. Antibacterial and antioxidant activity assay of the extract was carried out using the TLC Bioautography method. From the sixteen macrofungal extracts, there is one extract that has the strongest antibacterial activity compared to the others, namely n-hexane Coriolopsis polyzona. It showed moderate antibacterial activity against Staphylococcus aureus and Escherichia coli with MIC values of 256–128 μg/mL, respectively. Meanwhile, the antioxidant activity of the macrofungal extracts showed weak activity with IC50 values of 3080–7370 μg/mL (AAI values of 0.033–0.079).

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Section: Discussionmentioning

confidence: 99%

Bioprospection of Enggano Macroscopic Fungi as Antibacterial and Antioxidant Agents

et al. 2021

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“…Aktivitas antimikroba pada alpukat yang telah diekstrak dilakukan dengan mengamati besaran diameter hambat (⌀) dari ekstrak komponen buah alpukat terhadap pertumbuhan bakteri dan juga fungi yang diujikan di laboratorium. Aktivitas antimikroba pada ekstrak tumbuhan pada umumnya dilihat berdasarkan nilai diameter hambat yang secara garis besar dapat diklasifikasikan menjadi aktivitas antimikroba dengan kategori lemah (⌀0 -3 mm), kategori baik (⌀3 -6 mm), dan kategori kuat (⌀>6 mm) [18].…”

Section: Aktivitas Antimikroba Buah Alpukatunclassified

Review: Studi Kandungan Fitokimia dan Aktivitas Antimikroba Alpukat (Persea americana Mill)

Armida Asya Farhani,

Ni Putu Eka Leliqia

2023

WSNF

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Alpukat dengan nama spesies Persea americana Mill termasuk ke dalam family Lauraceae. Alpukat diketahui mampu berperan aktif sebagai agen antimikroba. Narrative review ini merupakan sebuah studi yang memiliki tujuan mengkaji penelitian-penelitian terbaru mengenai kandungan dari senyawa fitokimia beserta aktivitas antimikroba dari bagian-bagian tanaman alpukat. Studi literatur ini diperoleh dengan mengumpulkan, menganalisa, serta merangkum informasi dari artikel ilmiah yang berasal dari jurnal nasional maupun internasional. Berdasarkan hasil studi yang telah diperoleh menunjukkan berbagai macam ekstrak yang didapatkan mengandung golongan senyawa alkaloid, flavonoid, saponin, tanin, polifenol, kuinon, serta steroid dan triterpenoid. Bagian tanaman alpukat yang diketahui memiliki aktivitas antimikroba adalah biji, kulit buah, kulit batang, daun, dan daging buah yang diekstraksi menggunakan pelarut etanol, metanol, dan kloroform. Ekstrak tersebut terbukti dapat menghambat laju pertumbuhan bakteri Staphylococcus aureus, Escherichia coli, Salmonella typhi, dan Streptococcus mutans dengan rerata kategori diameter hambat kuat (>6 mm). Alpukat juga memiliki aktivitas antifungi yang termasuk kedalam kategori diameter hambat kuat terhadap jamur Candida albicans, Aspergillus niger, Trichophyton rubrum, Epidermophyton floccosum, Microsporum canis beserta jamur Colletotrichum. Berdasarkan keseluruhan aktivitas tersebut, diketahui bahwa ekstrak etanol biji alpukat paling aktif terhadap bakteri Streptococcus mutans (⌀12,8 mm), sedangkan ekstrak etanol kulit alpukat paling aktif terhadap jamur Aspergillus niger (⌀23,60 mm). Melalui narrative review ini, diharapkan dapat menjadi dasar untuk penelitian terbaru mengenai pemanfaatan kandungan senyawa fitokimia yang berperan dalam aktivitas antimikroba pada buah alpukat.

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“…Secara umum, jamur pangan mengandung lemak (1.7 %), karbohidrat (66.1%) dan protein (12.5%). Selain itu jamur pangan kaya akan kandungan vitamin seperti B1 (thiamin), B2 (riboflavin), B3 (niasin), B7 (biotin), C (asam askorbat) dan E (α-tokoferol) (Elfirta & Saskiawan 2020;Kadnikova et al 2015;Kim et al 2008). Jamur pangan mengandung berbagai senyawa yang bermanfaat bagi kesehatan, seperti polisakarida, asam organik, lipid, steroid, dan triterpen tetrasiklik (Vlasenko et al 2020).…”

Section: Pendahuluanunclassified

Kadar Karbohidrat dan Penapisan Senyawa Aktif dari Pleurotus pulmonarius yang Diekstraksi Menggunakan Metode Microwave Assisted Extraction (MAE) dengan Beberapa Perlakuan Suhu

Elfirta¹,

Saskiawan²,

Kasirah³

et al. 2023

JBI

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The majority of carbohydrates found in edible mushroom are in the form of polysaccharides, specifically beta-glucans. These beta-glucans have been reported as anticancer, antioxidant, and immunomodulator. This study aimed to investigate the potential of P. pulmonarius as functional food by comparing the carbohidrate content (total carbohydrate, beta-glucans, and reducing sugars) in P. pulmonarius extracted using microwave assisted extraction (MAE) at different temperatures: 60oC, 80oC and 100oC. Moreover, active compound screening was also conducted. MAE was chosen as the extraction method due to its short extraction time. The phenol-sulfiric acid method was used to measure total carbohydrates, while beta-glucan content was measured using the Megazyme Beta-Glucan Kit. Reducing sugar content was measured using the DNS (3,5-Di Nitro Salisilic Acid) and active compound screening was performed by qualitative method. The results showed that the highest total carbohydrates and beta-glucans were obtained at 60oC (75,089±0,012 mg/mL and 32,356±0,006% w/w respectively) while the highest reducing sugar content was obtained at 80oC (0,216±0,009 mg/mL). Active compound screening revealed the presence of flavonoids, saponins, and triterpenoids in each sample. These findings suggest that P. pulmonarius has potential as functional food since the rich content of beta-glucans and active compounds. The use of MAE at 60oC is more effective to extract P. pulmonarius compared with 80oC and 100oC.

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THE FUNCTIONAL CHARACTER OF Auricularia auricula CRUDE POLYSACCHARIDES: ANTIOXIDANT AND ANTIBACTERIAL ACTIVITY

Cited by 6 publications

References 26 publications

Bioprospection of Enggano Macroscopic Fungi as Antibacterial and Antioxidant Agents

Bioprospection of Enggano Macroscopic Fungi as Antibacterial and Antioxidant Agents

Review: Studi Kandungan Fitokimia dan Aktivitas Antimikroba Alpukat (Persea americana Mill)

Kadar Karbohidrat dan Penapisan Senyawa Aktif dari Pleurotus pulmonarius yang Diekstraksi Menggunakan Metode Microwave Assisted Extraction (MAE) dengan Beberapa Perlakuan Suhu

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