The function of the brain in olfaction. II. The results of destruction of olfactory and other nervous structures upon the discrimination of odors

Swann, H. G.

doi:10.1002/cne.900590202

Cited by 53 publications

(24 citation statements)

References 4 publications

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“…Although it contains the first neocortical olfactory representation, the orbital cortex most likely does not serve a functional role analogous to that of V1, S1, or A l . Many processes that might underlie olfactory perception occur at the level of the primary olfactory cortex, including olfactory detection, discrimination, and simple odor retention (Swann, 1934;Allen, 1940Allen, , 1941Eichenbaum et al, 1980;Staubli et al, 1987). Furthermore, there is a disynaptic link from the olfactory bulb to the amygdala and hippocampus (Schwerdtfeger et al, 1990) that can support both short-and long-term mnemonic functions as well as emotional processes (Staubli et al, 1984(Staubli et al, , 1986.…”

Section: Functional Considerationsmentioning

confidence: 99%

Central olfactory connections in the macaque monkey

Carmichael

Clugnet

Price

1994

J of Comparative Neurology

535

378

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The connections between the olfactory bulb, primary olfactory cortex, and olfactory related areas of the orbital cortex were defined in macaque monkeys with a combination of anterograde and retrograde axonal tracers and electrophysiological recording. Anterograde tracers placed into the olfactory bulb labeled axons in eight primary olfactory cortical areas: the anterior olfactory nucleus, piriform cortex, ventral tenia tecta, olfactory tubercle, anterior cortical nucleus of the amygdala, periamygdaloid cortex, and olfactory division of the entorhinal cortex. The bulbar axons terminate in the outer part of layer I throughout these areas and are most dense in areas that are close to the lateral olfactory tract. Labeled axons also were found in the superficial part of nucleus of the horizontal diagonal band. Retrograde tracers injected into the olfactory bulb labeled cells in the nucleus of the diagonal band and in all of the primary olfactory cortical areas except the olfactory tubercle. Electrical stimulation of the olfactory bulb evoked short-latency unit responses and a characteristic field wave in the primary olfactory cortex. Multiunit activity in layer II tended to be of shorter latency than that in layer III and the endopiriform nucleus. Associational connections within the primary olfactory cortex were demonstrated with anterograde tracer injections into the piriform cortex and the entorhinal cortex. Injections into the piriform cortex near the lateral olfactory tract labeled axons in the deep part of layer I of many primary olfactory areas, but especially in areas near the tract. An injection into the rostral entorhinal cortex, distant to the lateral olfactory tract, labeled a complementary distribution of axons in deep layer I of olfactory areas medial and caudoventral to the tract. This organization resembles that reported in the primary olfactory cortex of the rat [Luskin and Price (1983) J. Comp. Neurol. 216:264-291]. The anterograde tracer injections into the piriform cortex and retrograde tracer injections into the orbital and medial prefrontal cortex and rostral insula label connections from the primary olfactory cortex to nine areas in the caudal orbital cortex, including the agranular insula areas Iam, Iai, Ial, Iapm, and Iapl and areas 14c, 25, 13a, and 13m. The piriform cortex projects most heavily to layer I of these areas. Only Iam, Iapm, and 13a receive a substantial projection to the deeper layers. Areas Iam, Iapm, and 13a were also the only areas that responded with multiunit action potentials to olfactory bulb stimulation in anesthetized animals.(ABSTRACT TRUNCATED AT 400 WORDS)

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Section: Functional Considerationsmentioning

confidence: 99%

Central olfactory connections in the macaque monkey

Carmichael

Clugnet

Price

1994

J of Comparative Neurology

535

378

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“…These results indicate either that we have missed some simple cue, through inadequacy of technique, or that the same pattern of instinctive behavior may be initiated through different sense modalities and patterns of stimuli. Swann's studies of olfactory discrimination (44) showed that a remnant of the olfactory bulb too small to be identified by gross dissection may mediate olfactory discrimination. This fact might be urged against Stone's conclusions, but Beach has confirmed Stone's observations with animals in which complete destruction of the olfactory bulbs was verified by histological examination.…”

Section: Motor Action Based On Perceptual Organizationmentioning

confidence: 99%

Experimental analysis of instinctive behavior.

Lashley¹

1938

Psychological Review

276

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“…Although lesions in prepyriform cortex, periamygdaloid cortex, and the olfactory tubercle, all of which receive fibers from the olfactory bulb, produce degenerating fibers in the hippocampus and fascia dentata (Blackstad, 1958: Cragg, 1961, behavioral studies have not demonstrated any significant effect of hippocampal lesions on olfactory discrimination (Swann, 1934, 1935: Allen, 1940, 1941: Brown & Ghiselli, 1938. Only Brown and Ghiselli, however, have studied olfactory discrimination acquisition in hippocampally-lesioned rats, and these workers (as well as Swann) used creosote, which stimulates the trigeminal nerve as well as olfactory receptors (Allen, 1937) as one of the discriminanda.…”

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confidence: 99%