The French Version of the Modified-Checklist for Autism in Toddlers (M-CHAT): A Validation Study on a French Sample of 24 Month-Old Children

Baduel, Sophie; Guillon, Quentin; Afzali, Mohammad H.; Foudon, Nadège; Kruck, Jeanne; Rogé, Bernadette

doi:10.1007/s10803-016-2950-y

Cited by 39 publications

(44 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These different criteria may partly explain why the positive rate of level 1 screening in the study by Kamio et al was 17.23%, almost two‐fold higher than that in the studies of Chlebowski et al and Baduel et al In addition, differences in cultural background of the screened population and screening age appear to influence outcomes [Khowaja, Hazzard, & Robins, ]. In this study, the positive rate and referral show rate of level 1 screening during Stage I were lower than those in most previous studies, and the ASD diagnosis rate was lower than in all previous studies [Barid et al, ; VanDenHeuvel et al, ; Wu et al, ; Chlebowski et al, ; Kamio et al, ; Robins et al, ; Baduel et al, ]. The three aforementioned modifications in Stage II significantly increased these rates.…”

Section: Discussioncontrasting

confidence: 55%

“…Among seven domestic and international studies on early ASD screening with CHAT‐related instruments during routine well‐child visits, the positive rate of level 1 screening ranged from 1.37% to 17.23%, the show rate of referral from 9.80% to 81.90%; the level 2 positive rate from 18.75% to 56.67%, the show rate of referral from 63.50% to 100%, and the ASD diagnosis rate from 1.2/1,000 to 11/1,000 [Barid et al, ; VanDenHeuvel, Fitzgerald, Greiner, & Perry, ; Wu, Xu, Liu, & Cao, ; Chlebowski et al, ; Kamio et al, ; Robins et al, ; Baduel et al, ] (see Table for details). The variance among studies may stem from differing research methods and objectives.…”

Section: Discussionmentioning

confidence: 99%

“…The variance among studies may stem from differing research methods and objectives. For example, in the study of Kamio et al, the criterion for positivity on the M‐CHAT was failing any 3 of the 23 items or any 1 of the 10 critical items [Kamio et al, ], while in the studies of Chlebowski et al and Baduel et al, a positive screen was indicated by failure on 3 of the 23 items or 2 of 6 critical items [Chlebowski et al, ; Baduel et al, ]. These different criteria may partly explain why the positive rate of level 1 screening in the study by Kamio et al was 17.23%, almost two‐fold higher than that in the studies of Chlebowski et al and Baduel et al In addition, differences in cultural background of the screened population and screening age appear to influence outcomes [Khowaja, Hazzard, & Robins, ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Improving the early screening procedure for autism spectrum disorder in young children: Experience from a community‐based model in shanghai

Zhu²,

Feng

et al. 2018

Autism Research

View full text Add to dashboard Cite

Most children with autism spectrum disorder (ASD) are not diagnosed until the age of 4, thus missing the opportunity for early intervention. The objective of this study was to investigate the feasibility of an early screening program for ASD applied during well-child visits in a community-based sample. The study lasted for 4 years and was divided into two stages. Stage I involved the implementation of the basic screening model in 2014. Toddlers received level 1 screening via section A of the Chinese-validated version of the Checklist for Autism in Toddlers (CHAT-23) during 18- and 24-month well-child visits in Xuhui District, Shanghai, China. Screen-positive children were referred to receive section B of the CHAT-23 for level 2 screening, and those still screen-positive were referred to undergo diagnosis and evaluation. Stage II involved the implementation of the improved screening model from 2015 to 2017 with the following modifications: (a) an added observational component in level 1 screening; (b) telephone follow-ups with the screen-positive families; and (c) dissemination of information on ASD to families. The results showed that 42 of 22,247 screened children were diagnosed with ASD. The ASD diagnosis rates were 0.1% in Stage I and 0.21% in Stage II. The screen-positive rate and the show rate of referral for level 1 screening increased by 76.92% and 58.43%, respectively, in Stage II compared to Stage I. Our results suggest that with appropriate logistic support, this two-level screening model is feasible and effective for the early screening of ASD during well-child visits. Autism Res 2018, 11: 1206-1217. © 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: Difficulty in the timely identification of autism spectrum disorder (ASD) results in missed opportunities for many ASD children to receive early intervention. In this study, we established an early screening model for ASD among children aged 18-24 months in the community by relying on the three-level child healthcare system in China. The results showed that this model can effectively identify and diagnose ASD in children at an early age and thus enable early intervention.

show abstract

Section: Discussioncontrasting

confidence: 55%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Improving the early screening procedure for autism spectrum disorder in young children: Experience from a community‐based model in shanghai

Zhu²,

Feng

et al. 2018

Autism Research

View full text Add to dashboard Cite

show abstract

“…Children's general neurodevelopment at age 2 years was assessed using the Modified Checklist for Autism in Toddlers (M‐CHAT) questionnaire, a validated screening instrument for neurodevelopmental problems in children aged 16–30 months, including early signs of ASD [Baduel et al, ; Chlebowski et al, ]. The M‐CHAT questionnaire consists of 23 yes/no items [Chlebowski et al, ].…”

Section: Methodsmentioning

confidence: 99%

Maternal immigrant status and signs of neurodevelopmental problems in early childhood: The French representative ELFE birth cohort

et al. 2019

View full text Add to dashboard Cite

A growing body of evidence suggests that children of immigrants may have increased risks of neurodevelopmental disorders. However, evidence based on parent report and on very young children is lacking. We therefore investigated the association between maternal immigrant status and early signs of neurodevelopmental problems in a population‐based sample of 2‐year‐old children using standardized parent‐report instruments. We used data from the French representative Étude Longitudinale Française depuis l'Enfance birth cohort, initiated in 2011. The study sample included 9,900 children of nonimmigrant French, 1,403 children of second, and 1,171 children of first generation immigrant women followed‐up to age 2 years. Neurodevelopment was assessed using the Modified Checklist for Autism in Toddlers (M‐CHAT) and an adaptation of the MacArthur‐Bates Communicative Development Inventories (MB‐CDI). In fully adjusted linear regression models, maternal immigrant status was associated with M‐CHAT scores, with stronger associations in children of first (β‐coefficient: 0.19; 95% CI 0.08–0.29) than second generation immigrants (0.09; 0.01–0.17). This association was especially strong among children of first generation immigrant mothers native of North Africa (vs. nonimmigrant French: 0.33; 0.16–0.49) and French‐speaking Sub‐Saharan Africa (0.26; 0.07–0.45). MB‐CDI scores were lowest among children of first generation immigrant mothers, particularly from mostly non‐francophone regions. Children of first generation immigrant mothers were most likely to have simultaneously low MB‐CDI and high M‐CHAT scores. Our findings suggest that maternal immigrant status is associated with early signs of neurodevelopmental difficulties, with strong variations according to maternal region of origin. Further research is necessary to test whether these associations persist and to determine the underlying mechanisms. Autism Res 2019, 12: 1845–1859. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary We asked immigrant and nonimmigrant mothers in France about early signs of neurodevelopmental problems in their 2‐year‐old children. Overall, we found that children of immigrants may be at higher risk of showing these early warning signs, as compared to children of nonimmigrants. This is in line with previous studies, which were based on doctors' diagnoses at later ages. However, our results differed depending on the mothers' regions of origin. We found the highest risks in children of first generation immigrants from North and French‐speaking Sub‐Saharan Africa, who also seemed especially at risk of neurodevelopmental problems combined with low language development.

show abstract

“…M-CHAT includes a follow-up interview, which clarifies parent questionnaire responses to reduce false positives. M-CHAT has been assessed in multiple independent primary care samples116117 and internationally in multiple languages using validated translations 118119120121122. It is also available as an electronic tablet based version123; this product improves utilization by primary care pediatricians and can be completed by parents online, potentially increasing access by underserved populations 124.…”

Section: Screening and Surveillancementioning

confidence: 99%

Autism spectrum disorder: advances in diagnosis and evaluation

Zwaigenbaum

Penner

2018

BMJ

181

137

View full text Add to dashboard Cite

Autism spectrum disorder (ASD) has a variety of causes, and its clinical expression is generally associated with substantial disability throughout the lifespan. Recent advances have led to earlier diagnosis, and deep phenotyping efforts focused on high risk infants have helped advance the characterization of early behavioral trajectories. Moreover, biomarkers that measure early structural and functional connectivity, visual orienting, and other biological processes have shown promise in detecting the risk of autism spectrum disorder even before the emergence of overt behavioral symptoms. Despite these advances, the mean age of diagnosis is still 4-5 years. Because of the broad consistency in published guidelines, parameters for high quality comprehensive assessments are available; however, such models are resource intensive and high demand can result in greatly increased waiting times. This review describes advances in detecting early behavioral and biological markers, current options and controversies in screening for the disorder, and best practice in its diagnostic evaluation including emerging data on innovative service models.

show abstract

The French Version of the Modified-Checklist for Autism in Toddlers (M-CHAT): A Validation Study on a French Sample of 24 Month-Old Children

Cited by 39 publications

References 33 publications

Improving the early screening procedure for autism spectrum disorder in young children: Experience from a community‐based model in shanghai

Improving the early screening procedure for autism spectrum disorder in young children: Experience from a community‐based model in shanghai

Maternal immigrant status and signs of neurodevelopmental problems in early childhood: The French representative ELFE birth cohort

Autism spectrum disorder: advances in diagnosis and evaluation

Contact Info

Product

Resources

About