The formulation and characterization of 3D printed grafts as vascular access for potential use in hemodialysis

Bai, Chenglian; Xing, Yue; Shih, Nai Chia; Weng, Jen Po; Lin, Hsin‐Chieh

doi:10.1039/c8ra01583j

Cited by 8 publications

(8 citation statements)

References 55 publications

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“…It has been shown that, among cylindrical, twisted, and hexagonal designs of the outer rim of the 3D printed tubular grafts, the twisted design is more stable due to a better fusion of the layers. 61 Kinking of U shape small diameter vascular grafts in vivo precludes future clinical application. Therefore, designing the biodegradable vascular grafts with a corrugated structure can reduce the risk of kinking.…”

Section: Vascular Graftsmentioning

confidence: 99%

Incorporation of Controlled Release Systems Improves the Functionality of Biodegradable 3D Printed Cardiovascular Implants

Kabirian,

Mozafari,

Mela

et al. 2023

ACS Biomater. Sci. Eng.

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New horizons in cardiovascular research are opened by using 3D printing for biodegradable implants. This additive manufacturing approach allows the design and fabrication of complex structures according to the patient’s imaging data in an accurate, reproducible, cost-effective, and quick manner. Acellular cardiovascular implants produced from biodegradable materials have the potential to provide enough support for in situ tissue regeneration while gradually being replaced by neo-autologous tissue. Subsequently, they have the potential to prevent long-term complications. In this Review, we discuss the current status of 3D printing applications in the development of biodegradable cardiovascular implants with a focus on design, biomaterial selection, fabrication methods, and advantages of implantable controlled release systems. Moreover, we delve into the intricate challenges that accompany the clinical translation of these groundbreaking innovations, presenting a glimpse of potential solutions poised to enable the realization of these technologies in the realm of cardiovascular medicine.

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Section: Vascular Graftsmentioning

confidence: 99%

Incorporation of Controlled Release Systems Improves the Functionality of Biodegradable 3D Printed Cardiovascular Implants

Kabirian,

Mozafari,

Mela

et al. 2023

ACS Biomater. Sci. Eng.

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“…Therefore, a combination of the two may be another option. In a variety of techniques for skin constructs, the processing methods mainly consist of 3D printing, 45 electrospinning, 46 freeze drying, 47 etc . The choice of this process should satisfy scaffolds with high porosity and appropriate pore sizes.…”

Section: Fabrication Approaches For Prevascularized Skinmentioning

confidence: 99%

Strategies for vascularized skin modelsin vitro

et al. 2022

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“…Thus, there are various studies demonstrating the potential of 3D printed acrylate copolymers and acrylic polymers using the DLP system for vascular applications. Cheng et al 71 examined two different acrylate copolymers for arteriovenous graft (AVG) applications. Modified 4-acryloylmorpholine (ACMO) with trimethylolpropane triacrylate (TMPTA) and trimethylolpropane ethoxylate triacrylate (TMETA) was used as a 3D printing ink and PEGDA was used as a control material.…”

Section: Conventional Strategy For Developing Vascular Constructsmentioning

confidence: 99%

Freeform 3D printing of vascularized tissues: Challenges and strategies

et al. 2021

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In recent years, freeform three-dimensional (3D) printing has led to significant advances in the fabrication of artificial tissues with vascularized structures. This technique utilizes a supporting matrix that holds the extruded printing ink and ensures shape maintenance of the printed 3D constructs within the prescribed spatial precision. Since the printing nozzle can be translated omnidirectionally within the supporting matrix, freeform 3D printing is potentially applicable for the fabrication of complex 3D objects, incorporating curved, and irregular shaped vascular networks. To optimize freeform 3D printing quality and performance, the rheological properties of the printing ink and supporting matrix, and the material matching between them are of paramount importance. In this review, we shall compare conventional 3D printing and freeform 3D printing technologies for the fabrication of vascular constructs, and critically discuss their working principles and their advantages and disadvantages. We also provide the detailed material information of emerging printing inks and supporting matrices in recent freeform 3D printing studies. The accompanying challenges are further discussed, aiming to guide freeform 3D printing by the effective design and selection of the most appropriate materials/processes for the development of full-scale functional vascularized artificial tissues.

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The formulation and characterization of 3D printed grafts as vascular access for potential use in hemodialysis

Abstract: An arteriovenous graft that was successfully 3D printed with a novel printing ink formulation that displayed excellent mechanical and anti-fouling properties.

Cited by 8 publications

References 55 publications

Incorporation of Controlled Release Systems Improves the Functionality of Biodegradable 3D Printed Cardiovascular Implants

Incorporation of Controlled Release Systems Improves the Functionality of Biodegradable 3D Printed Cardiovascular Implants

Strategies for vascularized skin modelsin vitro

Freeform 3D printing of vascularized tissues: Challenges and strategies

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