Abstract:The ‘First Thousand Days’ refers to the period from conception to the child’s second birthday. It is increasingly gaining traction as a concept to guide public health policy. It is seen as a crucial window of opportunity for interventions that improve child and population health. This review outlines the origin and growth of the First Thousand Days concept, and the evidence behind it, particularly in the areas of brain development and cognition; mental and emotional health; nutrition and obesity; programming a… Show more
“…14 Specifically, a review suggested that early life circumstances are fundamental for good health in adulthood. 15 The period of "The First Thousand Days" of life (ie, the period from conception to the child's second birthday) is considered to provide a window of opportunity for early support of healthy growth and development of children. [16][17][18] This is in line with findings from Lee et al, 10 who suggested that poverty before age 2 was associated with the development of obesity in adolescence.…”
OBJECTIVES: In this study, we aim to assess the associations over time between poverty and child weight status, asthma, and health-related quality of life (HRQoL).
METHODS:We analyzed data for 3968 children from the Generation R Study, a population-based cohort study in the Netherlands. Net household income and the number of adults and children living from this income were measured at 4 time-points (during pregnancy and at ages 2, 3, and 6). Poverty was defined on the basis of the equivalized household income being ,60% of the median national income. Child health outcomes were measured at age 6 years. The association was explored by using logistic and linear regression models.RESULTS: In this cohort, 9.8% of children were born into poverty and 6.0% had experienced 3 to 4 episodes of poverty. Independent of current poverty status, children born into poverty had an odds ratio (OR) of 1.68 for having overweight/obesity and a lower physical HRQoL (OR = 21.32) than those not born into poverty. Children having experienced 3 to 4 episodes of poverty had an OR of 1.94 for having asthma and a lower physical HRQoL (OR = 23.32) compared with children from never-poor families. Transition out of poverty before age 2 was associated with lower risk of asthma and a higher physical HRQoL compared with children who remained in poverty.
CONCLUSIONS:Being born into poverty or experiencing multiple episodes of poverty is associated with negative child health outcomes, such as having overweight, asthma, or a lower HRQoL. Support for children and families with a low household income is warranted.
“…14 Specifically, a review suggested that early life circumstances are fundamental for good health in adulthood. 15 The period of "The First Thousand Days" of life (ie, the period from conception to the child's second birthday) is considered to provide a window of opportunity for early support of healthy growth and development of children. [16][17][18] This is in line with findings from Lee et al, 10 who suggested that poverty before age 2 was associated with the development of obesity in adolescence.…”
OBJECTIVES: In this study, we aim to assess the associations over time between poverty and child weight status, asthma, and health-related quality of life (HRQoL).
METHODS:We analyzed data for 3968 children from the Generation R Study, a population-based cohort study in the Netherlands. Net household income and the number of adults and children living from this income were measured at 4 time-points (during pregnancy and at ages 2, 3, and 6). Poverty was defined on the basis of the equivalized household income being ,60% of the median national income. Child health outcomes were measured at age 6 years. The association was explored by using logistic and linear regression models.RESULTS: In this cohort, 9.8% of children were born into poverty and 6.0% had experienced 3 to 4 episodes of poverty. Independent of current poverty status, children born into poverty had an odds ratio (OR) of 1.68 for having overweight/obesity and a lower physical HRQoL (OR = 21.32) than those not born into poverty. Children having experienced 3 to 4 episodes of poverty had an OR of 1.94 for having asthma and a lower physical HRQoL (OR = 23.32) compared with children from never-poor families. Transition out of poverty before age 2 was associated with lower risk of asthma and a higher physical HRQoL compared with children who remained in poverty.
CONCLUSIONS:Being born into poverty or experiencing multiple episodes of poverty is associated with negative child health outcomes, such as having overweight, asthma, or a lower HRQoL. Support for children and families with a low household income is warranted.
“…It refers to the period from conception to the child’s second birthday and is increasingly gaining traction as a concept for guiding public health policy. It is widely recognized as a crucial window of opportunity for interventions that improve child and population health [ 39 ]. In recent years, Gasbarrini et al have concentrated much effort on studying gut microbiota formation, establishment, and possibility of modulation in health and disease.…”
(1) Background: The purpose of the study was to comprehensively analyze the relationship between the mother’s oral microbiome, modes of delivery and feeding, and the formation of the newborn child’s oral microbiome. (2) Methods: This systematic review included a search through MEDLINE (PubMed) database (from 2010 to July 2020). Research was registered in PROSPERO under the number CRD42021241044. (3) Results: Of the 571 studies, 11 met the inclusion criteria. Included studies were classified according to (i) child’s delivery mode, (ii) maternal exposure to antibiotics and disinfectants, and (iii) feeding type. (4) Conclusions: The interpretation of these papers shows that the type of delivery, maternal exposure to disinfectants and antibiotics during delivery, maternal health classed as overweight, gestational diabetes mellitus, and feeding type are correlated to changes in the maternal and neonatal early oral microbiomes, based on the analysis provided in this systematic review. Because no evidence exists regarding the impact of maternal diet and maternal oral health on the establishment and development of the early oral newborn microbiome, more studies are needed to deepen the knowledge and understanding of the subject and develop preventive and therapeutic strategies of support to pregnant women.
“…As evidence increasingly highlights the importance of nutrition through the critical stages of development in the first 1000 days (Darling et al 2020 Two striking gaps in the methods for developing infant feeding guidelines were identified in this report: the lack of use of systematic review methodology and the infrequent use of a harmonized approach to setting guidelines across agencies or societies either within a country or across countries. The opportunity exists for Canada to build on the excellent foundation established by Health Canada and partner organizations to update the infant feeding recommendations of 2014-15 (Health Canada et al 2014;Health Canada et al 2015) and to expand them to include pre-conception, pregnancy and lactation.…”
A U.S. National Academies report summarized recommendations on what and how to feed infants and young children in high-income countries from 43 eligible guideline documents. Consistency existed across many recommendations, but some differences occurred in topic areas, age groupings and methodological approaches. Future development of guidelines on feeding of infants and young children requires new research and a rigorous evidence-based review process that is harmonized within and across countries and incorporates dissemination and implementation guidance.
Novelty:
• New research and rigorous methods are recommended to develop future harmonized guidance on feeding of infants and young children that incorporates dissemination and implementation methods.
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