The First Pediatric Patients with Coronavirus Disease 2019 (COVID-19) in Japan: Risk of Co-Infection with Other Respiratory Viruses

Kakuya, Fujio; Ōkubo, H.; Fujiyasu, Hiroaki; Wakabayashi, Iori; Syouji, Masayo; Kinebuchi, Takahiro

doi:10.7883/yoken.jjid.2020.181

Cited by 17 publications

(19 citation statements)

References 13 publications

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“…Cough: Initial symptoms were fever and cough; even among neonates 30 . Cough was experienced by the majority of patients, 10‐12,14,15,19,21‐93 it was mainly dry, but was sometimes followed by productive cough in moderately severe cases 19 . There may be upper airway symptoms, such as nasal congestion, rhinitis, and sore throat 19 .…”

Section: Resultsmentioning

confidence: 99%

“…Fever: One of the commonest early symptoms is fever, 11,14,15,19‐22,25‐36,38‐58,61‐65,67,68,70‐106 occasionally low grade. In Zhejiang province, fever clinics that exclusively accept for admission patients suspected of being positive for SARS‐CoV‐2 were set up 27 …”

Section: Resultsmentioning

confidence: 99%

“…Pneumonia/CT findings: Many pediatric patients had COVID‐19 pneumonia 10,11,16,19‐24,26,28‐31,34,38,40,42‐44,47‐54,56,57,60,61,64,66,68,70‐72,74‐76,78‐87,90‐92,94,95,99,100,103,155 and thoracic computerized tomography (CT) scan showed multifocal or nodular consolidation with ground glass opacities 11,15,16,19,22,23,26‐30,33,34,39,42‐44,47‐50,52‐54,60,61,64,66,72,74,78‐81,83‐86,91,95,100,103,107,164,165 . More adult patients had all five lobes affected 33,166 ; the manifestations of the COVID‐19 pneumonia are diverse and our understanding of the spectrum of disease is changing rapidly.…”

Section: Resultsmentioning

confidence: 99%

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Coronavirus global pandemic: An overview of current findings among pediatric patients

Perikleous

Tsalkidis

Bush

et al. 2020

Pediatric Pulmonology

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Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) epidemic has been emerged as a cardinal public health problem. Children have their own specific clinical features; notably, they seem to be escaping the severe respiratory adverse effects. The international scientific community is rapidly carrying out studies, driving to the need to reassess knowledge of the disease and therapeutic strategies. Aim To assess the characteristics of COVID‐19 infected children worldwide of all ages, from neonates to children and adolescents, and how they differ from their adult counterparts. Search Strategy An electronic search in PubMed was conducted, using combinations of the following keywords: coronavirus, SARS‐CoV‐2, COVID‐19, children. The search included all types of articles written in English between January 1, 2019 until August 15, 2020. Results The search identified 266 relevant articles. Children were mainly within family clusters of cases and have relatively milder clinical presentation compared with adults; children were reported to have better outcomes with a significantly lower mortality rate. Cough and fever were the most common symptoms while pneumonia was the cardinal respiratory manifestation of infected children. Laboratory results and thoracic imaging give varying results. Conclusions Children were mainly family cluster cases and usually presented with a mild infection, although cases presented with the multisystem inflammatory syndrome are becoming more apparent. Studies determining why the manifestations of SARS‐CoV‐2 infection are so variable may help to gain a better understanding of the disease and accelerate the development of vaccines and therapies.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Coronavirus global pandemic: An overview of current findings among pediatric patients

Perikleous

Tsalkidis

Bush

et al. 2020

Pediatric Pulmonology

View full text Add to dashboard Cite

show abstract

“…In the context of COVID-19, a small series of patients also found coinfections among children. 192 In contrast, however, studies from Norway and Kenya found an equal number of coronavirus identifications among both symptomatic and asymptomatic controls. 140,141 When some of these populations were also analyzed for episodes of coronavirus coinfections with other viruses, both groups had an approximately 68% frequency out of the total coronavirus infections.…”

Section: Studies Of High Putative Cofactor Incidencesmentioning

confidence: 93%

Complicating Infections Associated with Common Endemic Human Respiratory Coronaviruses

Cimolai

2021

Health Security

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“…During the beginning of the COVID-19 spread in Japan, influenza and human metapneumovirus were prevalent among children (the study was performed in the Furano region). Three children were diagnosed with COVID-19, two of whom were co-infected with influenza and human metapneumovirus [59].…”

Section: Co-infection Of Sars-cov-2 With Influenza-like Virusesmentioning

confidence: 99%

COVID-19 in Light of Seasonal Respiratory Infections

Kiseleva

Grigorieva

Larionova

et al. 2020

Biology

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A wide diversity of zoonotic viruses that are capable of overcoming host range barriers facilitate the emergence of new potentially pandemic viruses in the human population. When faced with a new virus that is rapidly emerging in the human population, we have a limited knowledge base to work with. The pandemic invasion of the new SARS-CoV-2 virus in 2019 provided a unique possibility to quickly learn more about the pathogenesis of respiratory viruses. In this review, the impact of pandemics on the circulation of seasonal respiratory viruses is considered. The emergence of novel respiratory viruses has often been accompanied by the disappearance of existing circulating strains. Some issues arising from the spread of pandemic viruses and underlying the choices of a strategy to fight the coronavirus infection are discussed.

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The First Pediatric Patients with Coronavirus Disease 2019 (COVID-19) in Japan: Risk of Co-Infection with Other Respiratory Viruses

Abstract: The first pediatric patients with coronavirus disease 2019 (COVID-19) in Japan;The risk of co-infection with other respiratory viruses

Cited by 17 publications

References 13 publications

Coronavirus global pandemic: An overview of current findings among pediatric patients

Coronavirus global pandemic: An overview of current findings among pediatric patients

Complicating Infections Associated with Common Endemic Human Respiratory Coronaviruses

COVID-19 in Light of Seasonal Respiratory Infections

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