“…No details were given of the methods of investigation or of the species of fungi isolated. Lumsden (1958) noted one case of A. niger infection in 148 infected mastoid cavities and Stride (i960) reported fungal infection in two of 60 infected cavities. In 1961 Gregson and La Touche reported fungal infection in 14 cavities which they treated by debridement and insufflation of nystatin powder.…”