The feasibility assessment of radiation dose of movement 3D NIPAM gel by magnetic resonance imaging

Hsieh, Chih-Ming; Leung, Joseph Hang; Ng, Yu-Bun; Cheng, C.Y.; Sun, Jung-Chang; Lin, Ping-Chin; Hsieh, Bor‐Tsung

doi:10.1016/j.radphyschem.2015.05.002

Cited by 7 publications

(1 citation statement)

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“…In 2015, Hsieh et al proposed a dynamic dose measurement applied to the calibration tube. They found that the dynamic dose response was similar to the static, and the average sensitivity difference of fixed and movement NIPAM was 0.001 s-1/Gy [7]. NIPAM gel dosimeters have also been used in static measurement, such as the study by Yao et al in 2019.…”

Section: Introductionmentioning

confidence: 99%

Applying the N-isopropylacrylamide gel dosimeter to quantify dynamic dose effects: A feasibility study

Sun

Hsieh

et al. 2022

THC

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BACKGROUND: The gel dosimeter is a chemical as well as a relative dosimeter. OBJECTIVE: To evaluate the feasibility of using N-isopropylacrylamide (NIPAM) gel dosimeter to observe the dynamic dose effects and quantification of the respiration, and to help determine the safety margins. METHODS: The NIPAM gel dosimeter combined with the dynamic phantom was used to simulate radiotherapy of lung or upper abdominal tumor. The field set to 4 × 5 cm2, simulate respiratory rate of 4 sec/cycle, and motion range 2 cm. MRI was used for reading, and MATLAB was used for analysis. The 3%/3 mm gamma passing rate > 95% was used as a clinical basis for evaluation. RESULTS: The dynamic dose curve was compared with 4 × 5, 4 × 4, 4 × 3 cm2 TPS, and gamma passing rates were 74.32%, 54.83%, 30.18%. Gamma mapping demonstrated that the highest dose region was similar to the result of the 4 × 4 cm2 TPS. After appropriate selection and comparing that the ⩾ 60% part of the dose curve with TPS, the gamma passing rate was 96.49%. CONCLUSIONS: Using the NIPAM gel dosimeter with dynamic phantom to simulate organ motion during respiration for dynamic dose measurement and quantified the dynamic dose effect is feasible. The results are consistent with clinical evaluation standards.

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Section: Introductionmentioning

confidence: 99%