The Fate of Suctioned and Surgically Removed Fat after Reimplantation for Soft-Tissue Augmentation

Kononas, Theodore C.; Bucky, Louis P.; Hurley, Christine; May, James W.

doi:10.1097/00006534-199304001-00001

Cited by 188 publications

(80 citation statements)

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“…This phenomenon explains the loss of effective filling of facial defects already evident before the 14-month follow-up (Kononas et al, 1993). Thus, clinical correction is directly determined by the surviving adipose tissue (Smahel, 1986), while the scarring fibrous tissue does not contribute to augmenting the soft tissue volume causing the graft retraction (May, 1990;Carpaneda and Ribeiro, 1994).…”

Section: Discussionmentioning

confidence: 99%

First Use of Stereology to Quantify the Survival of Fat Autografts

Cuellar¹,

Solís²

2011

Image Anal Stereol

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It is not usual to perform quantitative analyses on surgical materials. Rather, they are evaluated clinically, through qualitative methods, and if quantitation is done, it is on a 2-dimensional basis. In this study, the long-term survival of fat autografts (FAG) in 40 subjects with facial soft tissue defects is quantified. An adipose tissue preparation from the abdomen obtained through liposuction and centrifugation is injected subcutaneously. Approximately 14 months later, the treated area is biopsied. Extensive computer-based histological analyses were performed using the stereological method in order to directly obtain three parameters: volume fraction of adipocytes in the fat tissue (V V ), density (number per volume) of adipocytes in the fat tissue (N V ), and the mean cell volume of adipocytes (VA) in each tissue sample. A set of equations based on these three quantitative parameters is produced for evaluation of the volumetric survival fraction (VSF) of FAG. The presented data evidenced a 66% survival fraction at the 14-month follow-up. In routine practice, it would be sufficient to perform this volumetric analysis on the injected and biopsied fat samples to know what fraction of the FAG has survived. This is an objective method for quantifying FAG survival and will allow a standardized comparison between different research series and authors.

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Section: Discussionmentioning

confidence: 99%

First Use of Stereology to Quantify the Survival of Fat Autografts

Cuellar¹,

Solís²

2011

Image Anal Stereol

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“…Desde que a gordura foi proposta como material a ser utilizado para injeções intracordais 11 , muitos estudos têm abordado o problema da reabsorção da gordura no período pós-operatório e a conseqüente deterioração da qualidade vocal [4][5][6][8][9][10][11][12] . A literatura, contudo, é pobre no que tange à distribuição espacial da gordura injetada e seus efeitos sobre o contorno da borda livre, configuração glótica e alterações das propriedades viscoelásticas de cada camada da prega vocal.…”

Section: Discussionunclassified

Injeção de gordura na prega vocal: efeitos do local de injeção sobre a configuração glótica e a distribuição espacial da gordura injetada

Imamura

Sennes

Chung

et al. 2003

Rev. Bras. Otorrinolaringol.

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“…All of these may require multiple staged surgeries and even then in the best of cases may not achieve satisfactory appearance and function [2]. Autologous grafts are often considered the clinical gold standard, because allografts, xenografts, and synthetic materials are associated with complications such as pathogen transmission, immune rejection, and suboptimal integration [38][39][40][41][42][43].…”

Section: Tissue Substitutes For Facial Reconstructionmentioning

confidence: 99%

Evolution and Trends in Reconstructive Facial Surgery: An Update

Akadiri

2012

J. Maxillofac. Oral Surg.

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Surgical correction of congenital and acquired facial deformities has transcended the primitive era of using non biologic materials to current attempts at own face growing through biotechnology. A summative account of this trend is still lacking in the literature. The objective of this article is to present an update on current knowledge in the strides to achieve functionally and aesthetically perfect facial reconstruction. It highlights the impact of advancements in 3D imaging, stereolithographic biomodelling, microvascular surgical tissue transplantation and tissue biotechnology in the surgical efforts to solve the problems of facial disfigurement whether congenital or acquired.

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The Fate of Suctioned and Surgically Removed Fat after Reimplantation for Soft-Tissue Augmentation

Cited by 188 publications

References 0 publications

First Use of Stereology to Quantify the Survival of Fat Autografts

First Use of Stereology to Quantify the Survival of Fat Autografts

Injeção de gordura na prega vocal: efeitos do local de injeção sobre a configuração glótica e a distribuição espacial da gordura injetada

Evolution and Trends in Reconstructive Facial Surgery: An Update

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