The Fast Peritoneal Equilibration Test First and Second Hour Results

Abstract

Introduction. The Peritoneal Equilibration Test (PET) is employed to assess peritoneal membrane transport function. The purpose of the test is to determine the optimal peritoneal dialysis regimen. The performance of the test, which is conducted over 4 hours, is time consuming both for the nurses and the patient. There have been studies to validate an approved short version of the original PET protocol, and all have yielded different results. We evaluated the concordance between the 1-hour, 2-hour and 4-hour (classical) test results of the fast PET. Methods. The study included 32 patients (20 males and 12 females). The patients underwent the 4-hour fast PET test, and the dialysate-to-plasma ratio of creatinine concentration (D/Pcrea) was determined. The standard deviation was added to or subtracted from the mean D/Pcrea ratios at hours 1, 2, and 4 to determine transport groups. Results. The mean age of the patients was 51.4±16.7 years. Mean D/Pcrea ratios at hours 1, 2, and 4 were 0.41±0.07, 0.54±0.10, and 0.69+0.12, respectively. There was a strong correlation between the 4-hour D/Pcrea ratio and 1-hour (r=0.756, p<0.001) and 2-hour (r=0.867, p<0.001) D/Pcrea ratios. Seventeen patients (53%) were in the same transport group at hours 1, 2, and 4. Eighteen patients (56%) at 1 hour and 24 patients (75%) at 2 hours fell into the same transport group at 4 hours. The patients that fell into different transport groups at different time points showed a shift to a lower or higher transport group. Conclusions. Two-hour fast PET gives promising results for clinical assessment purposes.

Effluent plasminogen activator inhibitor 1 predicts ultrafiltration in incident peritoneal dialysis patients

“…First, a fast PET was used in the study because the one-hour dwell is more applicable in clinical after PD catheter insertion. A good correlation between the rst hour of fast PET and standard PET was supported in the previous study [10]. Second, The daily ultra ltration of the rst two days was analyzed, and the ultra ltration of the rst two days may not be consistent after two days.…”

“…Two patients with technique failure after PD catheter insertion were excluded because no e uent was available. We performed a fast PET after PD catheter insertion; e uent samples were collected at 1 hour, and a blood sample was collected at 1 hour [10]. The 1-hour D/P ratios of creatinine were calculated in all patients.…”