The evaluation of the effect of hypercalcemia in oral pathologies

Yücesoy, Türker; Şeker, Elif Dilara; Diker, Nurettin; Unver, Tugba; Vardar, Fatma

doi:10.1016/j.jormas.2020.09.012

Journal of Stomatology, Oral and Maxillofacial Surgery

2021

DOI: 10.1016/j.jormas.2020.09.012

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The evaluation of the effect of hypercalcemia in oral pathologies

Türker Yücesoy

Elif Dilara Şeker

Nurettin Diker

et al.

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2022

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“…Periodontal disease is known to be a common reason behind adult tooth loss (Hugoson et al, 2008). In addition, high S-Ca 2+ levels have been shown to be associated with alveolar bone loss and periodontal defects (Yucesoy et al, 2021). Thus, there are strong indications that pHPT has detrimental effects on the periodontal supporting tissues.…”

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Effects of primary hyperparathyroidism on oral health. A longitudinal register‐based study

et al. 2022

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ObjectivesTo analyze the effects of primary hyperparathyroidism on oral health and to investigate if the effects are linked to severity of the disease.Subjects and MethodsThis prospective cohort study involved 6151 primary hyperparathyroidism patients registered in the Scandinavian Quality Registry of Thyroid, Parathyroid, and Adrenal surgery and the National Cancer Register after parathyroidectomy (exposure) during 2011–2017 (patient cohort) and 60,654 individuals without primary hyperparathyroidism (reference cohort), matched by age, gender, and county of resident at the date of parathyroidectomy. The outcomes were tooth extractions and periodontal interventions. The risk for the outcomes was assessed by Poisson regression models.ResultsAfter adjusting for covariates, the patient cohort had a higher incidence rate of tooth extraction during the two‐year period after parathyroidectomy (IRR = 1.15; 95% CI = 1.01–1.31), but a lower incidence rate of periodontal interventions during the four‐ to six‐year period after parathyroidectomy (IRR = 0.88; 95% CI = 0.79–0.99). Furthermore, patients with more severe primary hyperparathyroidism were more likely to have tooth extractions and periodontal interventions after parathyroidectomy.ConclusionsThe risk of tooth extraction increased slightly during the first two years after parathyroidectomy. Thereafter, the oral health effects subsided. Pre‐surgical serum ionized calcium levels and adenoma weight may indicate negative dental outcomes after parathyroidectomy.

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Effects of primary hyperparathyroidism on oral health. A longitudinal register‐based study

et al. 2022

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The evaluation of the effect of hypercalcemia in oral pathologies

Cited by 1 publication

References 22 publications

Effects of primary hyperparathyroidism on oral health. A longitudinal register‐based study

Effects of primary hyperparathyroidism on oral health. A longitudinal register‐based study

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