The estimation of absorbed doses received by a victim of a Chinese radiation accident

On 26 April 1999, three persons were accidentally exposed by high dose (60)Co irradiation. They suffered from severe (one case) or moderate (two cases) hemopoietic form of acute radiation sickness (ARS). As part of the comprehensive treatment, strict reverse isolation and granulocyte-macrophage colony-stimulating factor (GM-CSF) therapy were applied. All the patients recovered after an appropriate treatment for 83 days. In our experience, the correct diagnosis and effective treatment at an early stage proved to be helpful to the patients in pulling out from the critical stage of acute radiation sickness. To avoid menstruation by the female patient just in the critical stage, we modified her menstruation cycle by testosterone. In our view, GM-CSF should be given as early as possible with enough dosage for promoting early hematological reconstruction. The experience obtained from the medical management of these patients is valuable for the treatment of such patients in the future.

show abstract

Reported Radiation Overexposure Accidents Worldwide, 1980-2013: A Systematic Review

Coeytaux¹,

Bey

Christensen³

et al. 2015

PLoS ONE

View full text Add to dashboard Cite

BackgroundRadiation overexposure accidents are rare but can have severe long-term health consequences. Although underreporting can be an issue, some extensive literature reviews of reported radiation overexposures have been performed and constitute a sound basis for conclusions on general trends. Building further on this work, we performed a systematic review that completes previous reviews and provides new information on characteristics and trends of reported radiation accidents.MethodsWe searched publications and reports from MEDLINE, EMBASE, the International Atomic Energy Agency, the International Radiation Protection Association, the United Nations Scientific Committee on the Effects of Atomic Radiation, the United States Nuclear Regulatory Commission, and the Radiation Emergency Assistance Center/Training Site radiation accident registry over 1980-2013. We retrieved the reported overexposure cases, systematically extracted selected information, and performed a descriptive analysis.Results297 out of 5189 publications and reports and 194 records from the REAC/TS registry met our eligibility criteria. From these, 634 reported radiation accidents were retrieved, involving 2390 overexposed people, of whom 190 died from their overexposure. The number of reported cases has decreased for all types of radiation use, but the medical one. 64% of retrieved overexposure cases occurred with the use of radiation therapy and fluoroscopy. Additionally, the types of reported accidents differed significantly across regions.ConclusionsThis review provides an updated and broader view of reported radiation overexposures. It suggests an overall decline in reported radiation overexposures over 1980-2013. The greatest share of reported overexposures occurred in the medical fields using radiation therapy and fluoroscopy; this larger number of reported overexposures accidents indicates the potential need for enhanced quality assurance programs. Our data also highlights variations in characteristics of reported accidents by region. The main limitation of this study is the likely underreporting of radiation overexposures. Ensuring a comprehensive monitoring and reporting of radiation overexposures is paramount to inform and tailor prevention interventions to local needs.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The estimation of absorbed doses received by a victim of a Chinese radiation accident

Cited by 3 publications

References 0 publications

Dose estimation by chromosome aberration analysis and micronucleus assays in victims accidentally exposed to⁶⁰Co radiation

Dose estimation by chromosome aberration analysis and micronucleus assays in victims accidentally exposed to⁶⁰Co radiation

Clinical Report of Three Cases of Acute Radiation Sickness from a 60Co Radiation Accident in Henan Province in China

Reported Radiation Overexposure Accidents Worldwide, 1980-2013: A Systematic Review

Contact Info

Product

Resources

About

The estimation of absorbed doses received by a victim of a Chinese radiation accident

Cited by 3 publications

References 0 publications

Dose estimation by chromosome aberration analysis and micronucleus assays in victims accidentally exposed to60Co radiation

Dose estimation by chromosome aberration analysis and micronucleus assays in victims accidentally exposed to60Co radiation

Clinical Report of Three Cases of Acute Radiation Sickness from a 60Co Radiation Accident in Henan Province in China

Reported Radiation Overexposure Accidents Worldwide, 1980-2013: A Systematic Review

Contact Info

Product

Resources

About

Dose estimation by chromosome aberration analysis and micronucleus assays in victims accidentally exposed to⁶⁰Co radiation

Dose estimation by chromosome aberration analysis and micronucleus assays in victims accidentally exposed to⁶⁰Co radiation