The estimated pulmonary artery pressure can be elevated in Behçet’s syndrome

Seyahi, Emire; Başkurt, Murat; Melikoğlu, Melike; Akman, Canan; Olgun, Deniz Çebi; Şimşek, Eda; Hamuryudan, Vedat; Küçükoğlu, Serdar; Yazıcı, Hasan

doi:10.1016/j.rmed.2011.07.022

Cited by 18 publications

(9 citation statements)

References 40 publications

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“…Hemoptysis due to pulmonary arterial aneurysms (PAA) should be differentiated from pulmonary emboli. Anticoagulant and fibrinolytic treatments given, based on a presumption of pulmonary emboli, may result in the death of patients with aneurysms (36). The diagnosis is confirmed by pulmonary angiography and CT.…”

Section: Prognosismentioning

confidence: 99%

Cardiac manifestations in Behcet's disease

Demirelli

Değirmenci

İnci

et al. 2015

IRDR

111

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Section: Prognosismentioning

confidence: 99%

Cardiac manifestations in Behcet's disease

Demirelli

Değirmenci

İnci

et al. 2015

IRDR

111

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“…In our study, we found that the levels of BNP, Cr, CRP, hsCRP were signi cantly higher in the valvular involvement group than in the non-valvular involvement group. Previous studies suggested that the elevated level of BNP in BD patients was associated with the heart strain and elevated risk of cardiac pump problems [18,19]. The serum Cr level was an independent predictor for heart failure hospitalizations [20].…”

Section: Discussionmentioning

confidence: 86%

Cardiac valvular involvement of Behçet’s disease

Liu

et al. 2022

Preprint

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The main objectives of the current study are to investigate valvular abnormality of Behçet’s disease (BD) patients with valvular involvement and find out the risk factors of valvular involvement in BD. We retrospectively assessed the clinical and echocardiographic data in the medical records of 121 patients with BD admitted to Beijing Anzhen Hospital from January 2015 to January 2022. We evaluated the valvular structure and function mainly by echocardiography. A total of 77 BD patients (77/121, 63.64%) had cardiac valvular involvement. Valvular lesions occurred more frequently in males (p = 0.022). Aortic regurgitation (AR) (62/77, 80.52%) was the most common finding and severe AR occupied 80.65% (50/62). The most common manifestations of BD patients with severe AR was aortic valve prolapse (25/50, 50%), followed by echo-free spaces within the aortic annulus (11/50, 22%), vegetation-like lesions (10/50, 20%), and aortic root aneurysm (10/50, 20%). The incidence of paravalvular leaks (PVL) in BD patients was 14.29% (7/49). The maximal diameter of the sinus of Valsalva and proximal ascending aorta, and total cholesterol (TCHO) were the independent risk factors of moderate-severe aortic valvular regurgitation (p < 0.01). Left ventricular end-diastolic dimension (LVEDD), left ventricular ejection fraction (LVEF) and brain natriuretic peptide (BNP) were significantly associated with moderate-severe mitral valvular regurgitation (p < 0.01). The most common valvular abnormality in BD is AR. Echocardiography has great value in the comprehensive evaluation and accurate diagnosis of valvular involvement in BD patients.

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“…In a controlled study among BS patients with and without pulmonary vascular disease, healthy controls, and patients with scleroderma included as diseased controls, we found out that close to 1/5 of BS patients had mildly (35-45 mmHg) elevated systolic pulmonary artery pressure (10). In addition, as in systemic sclerosis, some patients had impaired lung diffusion capacity and mild disturbances of cardiac function suggesting small vessel disease in these patients as well.…”

Section: Pulmonary Artery Hypertensionmentioning

confidence: 80%

Behçet syndrome: the vascular cluster

Yazıcı¹,

Seyahi²

2016

Turk J Med Sci

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Although skin-mucosa lesions are common in almost all patients with Behçet syndrome (BS), clinical properties may differ from one patient to another. Within BS, there are subsets with different organ involvement and hence probably different pathological pathways. These subsets can be described as a) solo skin-mucosa disease with no major organ involvement, b) eye disease, c) seronegative spondyloarthropathy-like disease (arthritis, enthesopathy, and folliculitis), d) Crohn-like disease, and finally the topic of this chapter: e) vascular disease. In the vascular disease subset, not surprisingly, several types of vascular involvement may be observed in the same individual. These subsets may make up the total clinical picture all at the same time or step by step with each relapse. Significant correlations exist between cerebral vascular thrombosis and pulmonary artery involvement, intracardiac thrombi and pulmonary artery involvement, Budd-Chiari syndrome, and inferior vena cava syndrome. Lower extremity vein thrombosis is often present in these associations and even precedes them. The recognition of these clusters is not only important in diagnosis and management but also in basic science, including genetic studies.

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The estimated pulmonary artery pressure can be elevated in Behçet’s syndrome

Cited by 18 publications

References 40 publications

Cardiac manifestations in Behcet's disease

Cardiac manifestations in Behcet's disease

Cardiac valvular involvement of Behçet’s disease

Behçet syndrome: the vascular cluster

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The estimated pulmonary artery pressure can be elevated in Behçet’s syndrome

Cited by 18 publications

References 40 publications

Cardiac manifestations in Behcet&apos;s disease

Cardiac manifestations in Behcet&apos;s disease

Cardiac valvular involvement of Behçet’s disease

Behçet syndrome: the vascular cluster

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Cardiac manifestations in Behcet's disease

Cardiac manifestations in Behcet's disease