The Essential Oil of Cupressus Macrocarpa

Briggs, Lindsay H.; Sutherland, M. D.

doi:10.1021/jo01199a001

Cited by 29 publications

(18 citation statements)

References 8 publications

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“…It showed the presence of 39 compounds that belong to various phytochemical subclasses such as organic acids, phenolics, coumarins, flavonoids, biflavonoids, polyflavonoids, catechins, flavonoid glycosides, stilbene, and triterpene saponins (Table 1). These compounds were identified based on the m/z of molecular ion [M-H] − and interpretation of the MS and MS/MS spectra comparison with the library (in-house database) and previously reported literature [14][15][16][17][18][19]. Structures of the identified compounds are displayed in Figure S2.…”

Section: Metabolite Profiling Of the C Macrocarpa Roots Methanol Extractmentioning

confidence: 99%

“…Despite being a decorative plant, C. macrocarpa has different pharmacological activities such as anti-inflammatory, hepatoprotective, nephroprotective, insecticidal, cytotoxic, and antiviral [10][11][12][13]. There have been numerous contributions to the composition of C. macrocarpa essential oil or other constituents in leaves [14][15][16][17], but to our knowledge, there has never been a comprehensive study on the roots of this plant. Here, we investigate the phytochemical profiling for methanol extract of C. macrocarpa roots by LC-ESI-MS/MS.…”

Section: Introductionmentioning

confidence: 99%

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Antidiarrheal and Antibacterial Activities of Monterey Cypress Phytochemicals: In Vivo and In Vitro Approach

et al. 2022

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Monterey cypress (Cupressus macrocarpa) is a decorative plant; however, it possesses various pharmacological activities. Therefore, we explored the phytochemical profile of C. macrocarpa root methanol extract (CRME) for the first time. Moreover, we investigated its antidiarrheal (in vivo), antibacterial, and antibiofilm (in vitro) activities against Salmonella enterica clinical isolates. The LC-ESI-MS/MS analysis of CRME detected the presence of 39 compounds, besides isolation of 2,3,2″,3″-tetrahydro-4′-O-methyl amentoflavone, amentoflavone, and dihydrokaempferol-3-O-α-l-rhamnoside for the first time. Dihydrokaempferol-3-O-α-l-rhamnoside presented the highest antimicrobial activity and the range of values of MICs against S. enterica isolates was from 64 to 256 µg/mL. The antidiarrheal activity of CRME was investigated by induction of diarrhea using castor oil, and exhibited a significant reduction in diarrhea and defecation frequency at all doses, enteropooling (at 400 mg/kg), and gastrointestinal motility (at 200, 400 mg/kg) in mice. The antidiarrheal index of CRME increased in a dose-dependent manner. The effect of CRME on various membrane characters of S. enterica was studied after typing the isolates by ERIC-PCR. Its impact on efflux and its antibiofilm activity were inspected. The biofilm morphology was observed using light and scanning electron microscopes. The effect on efflux activity and biofilm formation was further elucidated using qRT-PCR. A significant increase in inner and outer membrane permeability and a significant decrease in integrity and depolarization (using flow cytometry) were detected with variable percentages. Furthermore, a significant reduction in efflux and biofilm formation was observed. Therefore, CRME could be a promising source for treatment of gastrointestinal tract diseases.

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Section: Metabolite Profiling Of the C Macrocarpa Roots Methanol Extractmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antidiarrheal and Antibacterial Activities of Monterey Cypress Phytochemicals: In Vivo and In Vitro Approach

et al. 2022

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“…All of the north-coastal Cupressus species produce an essential oil that is low in sesquiterpenoids (Zavarin et al, 1971). Briggs and Sutherland (1942) analyzed C. macrocarpa foliar oil by fractional distillation and reported only ca. 0.7% for the sesquiterpene fraction of the oil.…”

Section: R E V I E W C O P Y Introductionmentioning

confidence: 99%

Sesquiterpenes from Cupressus macrocarpa foliage

Cool¹

2005

Phytochemistry

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Ten sesquiterpenes, many with unusual carbon skeletons, were identified in foliage of Cupressus macrocarpa. These are (-)-10-epi-beta-acoradiene; ent-widdra-2,4(14)-diene; (E)-iso-gamma-bisabolene, i.e., (4E)-4-(1,5-dimethylhex-5-enylidene)-1-methylcyclohexene; (-)-cumacrene, i.e., (4S)-4-[(1R,2S)-2-isopropenyl-1-methylcyclobutyl]-1-methylcyclohexene; (-)-alpha-chamipinene, i.e., (1S,6S,7S)-2,2,6,8-tetramethyltricyclo[5.3.1.01,6]undec-8-ene; and five sesquiterpenes with a 3,3,4'-trimethyl-1,1'-bi(cyclohexyl) skeleton for which the trivial name macrocarpane is proposed. The possible single-enzyme biogenesis of these sesquiterpenes is discussed.

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“…Spices were added during CFBS fermentation in order to enhance aroma (Li, 1999;Liao et al, 2005). Styrene, representing 0.36% of the total, was also reported in the clove oils (Briggs et al, 1942). α-Farnesene (0.65%), zingiberene (2.62%), β-Bisabolene (0.54%) and sesquiphellandrene (1.24%) were identified in volatile contents of ginger oil (Russell et al, 1968;Nishimura, 1995;Connell et al, 1971;Lawrence, 1995).…”

Section: Resultsmentioning

confidence: 98%

Comparison of Volatile Flavor Components in Four Kinds of Chinese Fermented Black Soybeans (Glycine max (L.) Merrill) by HS-SPME-GC/MS and Chemometrics

Xiao

Zongyu

Feng

et al. 2011

FSTR

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The applicability of headspace solid-phase micro-extraction (HS-SPME) combined with gas chromatography and mass spectrometry (GC/MS) for determination of volatile flavor components (VFCs) of 4 kinds of Chinese fermented black soybeans (CFBS) collected from 4 different regions of China (Chongqing Yongchuan, Guangdong Yangjiang, Hunan Liuyang and Jiangxi Hukow, respectively). Principal component analysis (PCA) was used to visually compare their VFCs. Sixty-five VFCs were identified from 4 kinds of CFBS. These VFCs were divided into 11 categories including 13 acids, 7 alkenes, 7 alcohols, 6 aldehydes, 10 esters, 1 ether, 3 ketones, 5 phenols, 9 pyrazines,1 sulfide and 3 miscellaneous. In PCA comparison, Chongqing Yongchuan had the highest amount of phenethyl alcohol responsible for intense sauce-like aroma. Guangdong Yangjiang characterized by ginger aroma, was rich in zingiberene. Hunan Liuyang had stronger fatty aroma because of its higher ester content, while Jiangxi Hukow was richer in nutty aroma due to its plentiful pyrazines.

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The Essential Oil of Cupressus Macrocarpa

Cited by 29 publications

References 8 publications

Antidiarrheal and Antibacterial Activities of Monterey Cypress Phytochemicals: In Vivo and In Vitro Approach

Antidiarrheal and Antibacterial Activities of Monterey Cypress Phytochemicals: In Vivo and In Vitro Approach

Sesquiterpenes from Cupressus macrocarpa foliage

Comparison of Volatile Flavor Components in Four Kinds of Chinese Fermented Black Soybeans (Glycine max (L.) Merrill) by HS-SPME-GC/MS and Chemometrics

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