The epidemiology of wrist fractures in older men: the Osteoporotic Fractures in Men (MrOS) study

Wright, Nicole C.; Hooker, Elizabeth R.; Nielson, Carrie M.; Ensrud, Kristine E.; Harrison, Stephanie L.; Orwoll, Eric S.; Barrett‐Connor, Elizabeth

doi:10.1007/s00198-017-4349-9

Cited by 20 publications

(19 citation statements)

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“…The prevalence of fragility fractures is 20.5% in women ≥65 years old in the United States (US), [ 3 ] and the annual incidence of distal radius fracture for men aged ≥65 is approximately 160 per 100,000 persons in the US. [ 4 ] In Korea, the annual incidence of distal radius fractures is 246 to 278 per 100,000 persons [ 5 ] and of hip fractures is approximately 1500 in women and 5000 in men. [ 6 ] The incidence of spine fracture in Korea is estimated to be 526 to 544 per 100,000 persons in men and 1.58 to 1.60 per 100,000 persons in women; these values are higher than the worldwide incidence, which ranged from 48 to 1083 per 100,000 persons.…”

Section: Introductionmentioning

confidence: 99%

Increased risk of dementia after distal radius, hip, and spine fractures

et al. 2020

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Section: Introductionmentioning

confidence: 99%

Increased risk of dementia after distal radius, hip, and spine fractures

et al. 2020

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“…We also found that the incidence of the rst wrist fracture after the age of 50 was higher in women than in men, which was supported by the Oslo Health Study [22]. Women ages above 50 are usually in or about to enter their menopause, who are at higher risk of osteoporosis that may lead to brittle fractures [6,13,[26][27][28].…”

Section: Discussionmentioning

confidence: 57%

“…Therefore, it is high time that we design more studies to assess the prevalence, characteristics and associated risk factors of wrist fracture, contributing to their prevention and treatment measures. However, epidemiological studies on that incidence of wrist fractures were limited [5,13]. There has not been reports on the prevalence of wrist fractures yet.…”

Section: Introductionmentioning

confidence: 99%

Prevalence, Characteristics, and Associated Risk Factors of Wrist Fractures in Americans Above 50: the Cross-sectional NHANES Study

Nie

2021

Preprint

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BackgroundWrist fractures, also known as distal radius fractures, are the most common fractures occurred in the upper limb. This study is conducted in the purpose of evaluating the prevalence, characteristics, and associated factors of wrist fractures in Americans that aged 50 and above.MethodsData of Americans aged 50 or above from the year 2013 to 2014 and 2017 to 2018 in NHANES was extracted and analyzed. Based on orthopedist's diagnosis, we further conducted surveys to determine the condition of wrist fractures, and collected relevant epidemiological and demographic data. The prevalence of wrist fractures and other statistics were calculated to study population characteristics and analyze potential risk factors associated with wrist fractures.ResultsThe prevalence of wrist fractures among Americans whose age was 50 or above was 12%, with similar results between men and women patients (male 12.8 % vs female 11.4 %, P = 0.267). Male and female Americans’ first wrist fracture occurred at a mean age of 29.4. 17.8% of Americans aged 50 and above had experienced two fractures, while 1.7% of Americans even experienced four or more fractures. The top two causes of the first fracture were falling down from standing height (56%) and violent falls (34.8%). Multivariate analysis showed that osteoporosis (OR = 2.2, 95% CI = 1.7-2.9), excessive drinking (OR = 1.8, 95% CI = 1.3-2.4), smoking (OR = 1.6, 95% CI = 1.2-2.1), prednisolone administration (OR = 1.5, 95% CI = 1.1-2.1) and obesity (OR = 0.8, 95% CI = 0.6-0.9) were independently associated with wrist fractures. Gender was not an independent risk factor associated with wrist fractures.ConclusionsThe prevalence of wrist fractures in Americans aged 50 and above was 12 %. The prevalence was similar between male and female patients. Falling from a standing height was the main cause of the first wrist fracture. Osteoporosis, excessive drinking, smoking and prednisolone administration were risk factors of wrist fractures, while obesity was negatively correlated.

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“…In addition to trauma, bone healing problems are usually associated with several factors, such as age, sex and infection, as demonstrated by diagnoses, such as osteopenia, osteoporosis and severe dental problems related to tooth loss [12]. For instance, osteoporosis has been recognized as one of the most important disease afflicting the global population alongside hypertension and diabetes mellitus [33], whereas its economic impact is similar to the cost of other major diseases, such as strokes, breast cancer or myocardial infarction. It is characterized by an imbalance in the bone remodeling process that leads to a progressive loss in bone mass and, subsequently, an increase in the fracture risk [34].…”

Section: Bone Fracture and Diseasesmentioning

confidence: 99%

Innovative Biomaterials for Bone Regrowth

Iaquinta

Mazzoni

Manfrini

et al. 2019

IJMS

126

101

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The regenerative medicine, a new discipline that merges biological sciences and the fundamental of engineering to develop biological substitutes, has greatly benefited from recent advances in the material engineering and the role of stem cells in tissue regeneration. Regenerative medicine strategies, involving the combination of biomaterials/scaffolds, cells, and bioactive agents, have been of great interest especially for the repair of damaged bone and bone regrowth. In the last few years, the life expectancy of our population has progressively increased. Aging has highlighted the need for intervention on human bone with biocompatible materials that show high performance for the regeneration of the bone, efficiently and in a short time. In this review, the different aspects of tissue engineering applied to bone engineering were taken into consideration. The first part of this review introduces the bone cellular biology/molecular genetics. Data on biomaterials, stem cells, and specific growth factors for the bone regrowth are reported in this review.

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The epidemiology of wrist fractures in older men: the Osteoporotic Fractures in Men (MrOS) study

Cited by 20 publications

References 43 publications

Increased risk of dementia after distal radius, hip, and spine fractures

Increased risk of dementia after distal radius, hip, and spine fractures

Prevalence, Characteristics, and Associated Risk Factors of Wrist Fractures in Americans Above 50: the Cross-sectional NHANES Study

Innovative Biomaterials for Bone Regrowth

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