The epidemiology and health burden of neurocysticercosis in tertiary hospital of Nepal

Sah, RB; Subedi, Laxmi; Pandey, Naveen; Sah, BP; Jha, Shivendra; Shah, Utkarsh; Jha, Nilambar; Pokharel, PK

doi:10.3126/jcmc.v4i2.10854

Cited by 4 publications

(5 citation statements)

References 14 publications

(12 reference statements)

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“…In another study done at Dharan, of the 114 in-patient cases of neurocysticercosis, 63% patients were male and 42% were in age group <20years. 16 Proportion of male patients in this study is very similar to our series.Mean age in 62 histopathology proven case of NCC patients was 21 years which was slightly lower than our finding of 27.9 years. 17 Many clinical experience of NCC reported from Nepal have found different presentation and treatment responses.…”

Section: Discussionsupporting

confidence: 88%

Demographics and Pharmacotherapy in Neurocysticercosis: A hospital Based Study

Shrestha

Rajbhandari

et al. 2021

Annapurna J H Sci

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Introduction: Neurocysticercosis (NCC) is one of the commonest preventable cause of seizure. It is due to development of the larval form of Taenia solium. This disease is endemic in south east Asia including Nepal and has been considered as one of the neglected tropical disease. Methods: All the patients who came to Neurosurgical outpatient department (OPD) of Annapurna Neurological Institute and Allied Sciences (ANIAS) with the diagnosis of NCC with seizure during the study time frame were included in the study. The time frame of the study was January 1st 2017 till December 31st 2018. Results: There were 167 total cases of which 108 (64.7%) were male and 59 (35.3%) were female. Mean age was 27.9 years (SD 13.1 years, range 1 year to 66 years). Frequency of patients were in the age group 20-30 years followed by 10-20 years. In terms of number of lesions, 86% of the patients had single lesion while 14% had multiple lesionsMaximum number of cases had focal seizure with secondary generalization (46%). This was followed by focal seizure (28%). Most common antiepileptics was carbamazepine (51.5%).Mean duration of antiepileptics was 2.5 years (SD 1.47, Range 9 months to 6 years) and recurrence was noted in 7.78% of cases. Conclusion: NCC affects the productive age group with higher proportion being male patient. Single lesion is more prevalent. Proper measures for treatment and prevention of neurocysticercosis is essential and can lead to better control of this condition.

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Section: Discussionsupporting

confidence: 88%

Demographics and Pharmacotherapy in Neurocysticercosis: A hospital Based Study

Shrestha

Rajbhandari

et al. 2021

Annapurna J H Sci

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“…9 The study done by Sah and Jha in a tertiary care hospital showed rising prevalence of diabetes with increasing age with more cases among male than female. 10 In contradiction, our research shows more diabetic cases among female than male. This can be attributed to the different study settings and sociodemographic pattern.…”

Section: Discussioncontrasting

confidence: 78%

Prevalence of Type II Diabetes Mellitus Among Adult Population in Medical Department of A Tertiary Care Centre

Karki¹,

Rana²,

Shahi³

et al. 2020

J Nepal Med Assoc

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Introduction: Diabetes mellitus is a chronic metabolic disease that is mainly associated with a number of lifestyle behaviors. There is a high discrepancy among urban and rural populations with the prevalence of diabetes in rural areas as 2.5% and a high prevalence of 14.6% in urban areas. Type 2 diabetes mellitus accounts for the majority of all diabetes cases with a number of chronic effects that include cardiovascular disease, kidney disease, blindness, and disability. This study is done to determine the prevalence of Type II Diabetes Mellitus among the adult population in the medical department of a tertiary care center. Methods: A descriptive cross-sectional study was done in a medical department of a tertiary care center of Himal Hospital Private Limited from March to April 2020. Ethical approval was taken from the Ethical Review Board of NHRC (Reference Number 752). All the data of the last two years from the medical record section were included in the study. The convenience sampling technique was followed. Descriptive statistical analysis was done. Results: The study showed the prevalence of Type II Diabetes Mellitus among the adult population to be 23.93 % (0.23) (C.I= 0.20-0.26). Prevalence was found to be ... Conclusions: The prevalence of Type II Diabetes Mellitus was found to be higher than the previous study done in similar settings.

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“…[2] Cross reactivity of Ig G is also well documented. [10] Agreement for IgM / IgG between ICT and ELISA were only 80% and 80.8% respectively in this study.…”

Section: Discussioncontrasting

confidence: 63%

“…However, IgM is more specific than IgG to detect acute infection. [9,10] The ICT may be evaluated for this purpose at field level by testing paired samples.…”

Section: Discussionmentioning

confidence: 99%

Rapid immunochromatographic test to detect NS1antigen, Ig M and Ig G: An alternative to enzyme linked immunosorbent assay in diagnosis of dengue at primary care level.

Lakshmi¹,

Palaniappan²

2014

JCBS

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Background: During the recent outbreak of Dengue, there was an alarming increase in the morbidity and mortality in the southern districts of Tamilnadu. Early diagnosis and differentiation of primary and secondary dengue is essential for treat-ment and control measures. Objective: This study was done to compare rapid immunochromatography (ICT) and ELISA in the early diagnosis of dengue by the simultaneous detection of IgM, IgG and NS1 antigen. Methods: Sera from 120 suspected dengue fever patients were tested for IgM, IgG and NS1 antigen by ICT and ELISA methods. Results: Among the tested 120 samples, 37 (31%) for any one marker, 18 (15%) for NS1antigen, 18(15%) for IgM and 25 (21%) for IgG were positive by ICT. By ELISA 58(48%) for any one marker, 22(18%) for NS1, 42(35%) for IgM, and 48 (40%) for IgG were positive. Conclusion: In view of high degree of agreement (96.7%) between ICT and ELISA for NS1 detection, the rapid ICT may be useful at field level particularly where ELISA is not available for the early diagnosis and effective intervention.

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The epidemiology and health burden of neurocysticercosis in tertiary hospital of Nepal

Cited by 4 publications

References 14 publications

Demographics and Pharmacotherapy in Neurocysticercosis: A hospital Based Study

Demographics and Pharmacotherapy in Neurocysticercosis: A hospital Based Study

Prevalence of Type II Diabetes Mellitus Among Adult Population in Medical Department of A Tertiary Care Centre

Rapid immunochromatographic test to detect NS1antigen, Ig M and Ig G: An alternative to enzyme linked immunosorbent assay in diagnosis of dengue at primary care level.

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