The endocrine control by luteinizing hormone of testosterone secretion from the testis of the Japanese quail

Maung, Shwe Lu; Follett, B. K.

doi:10.1016/0016-6480(78)90053-9

Cited by 45 publications

(10 citation statements)

References 39 publications

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“…The significantly lower concentration of LH in the plasma of hemicastrated birds than in intact cockerels between 8 and 11 weeks could have been the consequence of the raised LH levels between 4 and 6 weeks of age stimulating the secretion of testicular hormones (Brown, Bayle, Scanes & Follett, 1975;Maung & Follett, 1978). …”

Section: Resultsmentioning

confidence: 94%

Concentrations of Luteinizing Hormone in the Plasma of Hemicastrated Cockerels

Wilson¹,

Reviers²

1979

Journal of Endocrinology

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The concentrations of LH in plasma were measured, using a radioimmunoassay, during sexual development of intact cockerels and cockerels hemicastrated at 2 weeks of age. The pattern of LH secretion during maturation was characterized by a series of at least four consistently observed periods of rising and falling blood levels of the hormone. Levels of luteinizing hormone were higher in hemicastrated than in intact cockerels between 2 and 4 weeks after the operation (4--6 weeks of age) and then fell to values below those seen in intact cockerels between 8 and 11 weeks of age. Thereafter, until 28 weeks of age, levels of LH in plasma in both hemicastrated and intact birds were similar. The transient changes in LH concentration after hemicastration were thought to be a direct consequence of an alteration in the concentration of testicular steroids in the blood after the removal of one gonad.

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Section: Resultsmentioning

confidence: 94%

Concentrations of Luteinizing Hormone in the Plasma of Hemicastrated Cockerels

Wilson¹,

Reviers²

1979

Journal of Endocrinology

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“…The increase in testosterone and inhibin is probably caused by LH. The stimulation by LH of testosterone secretion in Leydig cells is well known (Maung and Follet, 1978). Recently, Risbridger et al (1989) demonstrated in rats that LH also stimulates the secretion of immunoreactive inhibin in Leydig cells.…”

Section: Discussionmentioning

confidence: 97%

Developmental changes in immunoreactive inhibin and FSH in plasma of chickens from hatch to sexual maturity

Vanmontfort¹,

Berghman²,

Rombauts³

et al. 1995

British Poultry Science

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1. The relationship between immunoreactive inhibin and follicle-stimulating hormone (FSH) was studied in male and female chickens from hatch to sexual maturity. Plasma inhibin was estimated by a heterologous radioimmunoassay validated for use in the chicken. FSH was measured by a recently developed homologous radioimmunoassay. 2. In a cross-sectional study, blood samples and gonads were collected from chickens of both sexes at 1, 3, 5, 7, 14, 21 and 28 d after hatching and subsequently at 14-day intervals until 182 d of age. 3. In the female, plasma progesterone concentration (P4) progressively increased during sexual development. The plasma luteinising hormone (LH) concentration rose during the first week after hatching, and fluctuated thereafter, with troughs at 6 and 14 weeks and peaks at weeks 10 and 18. The plasma inhibin and FSH concentrations remained low until the start of puberty and increased simultaneously thereafter. However, from week 18 on, plasma inhibin continued to rise while plasma FSH fell. Hence, FSH and inhibin were positively correlated before puberty, but developed a negative correlation during sexual maturation. 4. In the male, plasma testosterone and LH concentrations increased 38- and 3.7-fold respectively over the period studied. Inhibin and FSH followed similar time courses and were consequently positively correlated. 5. These results suggest sex differences in the role of inhibin in regulating FSH secretion during development. The FSH-inhibin feedback loop may become operational at the onset of sexual maturity in the hens. In male chickens, the similar pattern of inhibin and FSH secretion suggests that inhibin secretion is driven by FSH.

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“…The increase in testosterone and ir-inhibin from Leydig cells is probably caused by LH. Feedback control of LH by testosterone is also well known [32,33]. Risbridger et al [34] …”

Section: Discussionmentioning

confidence: 99%

Secretion of Inhibin in Male Japanese Quail (<i>Coturnix japonica</i>) from One Week of Age to Sexual Maturity

Sedqyar

Wang

Watanabe

et al. 2008

Journal of Reproduction and Development

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Abstract. The objective of this study was to investigate the changes in secretion of inhibin and cellular localization of the inhibin α and inhibin/activin (βA and βB) subunits in male Japanese quail from 1 to 7 weeks after hatching. The posthatch profile of plasma luteinizing hormone (LH), immunoreactive (ir) inhibin and testosterone were measured by radioimmunoassay. Testes were immunostained by the avidin-biotin-peroxidase complex method (ABC) using polyclonal antisera raised against inhibin α, inhibin/activin βA and inhibin/activin βB from one week of age to sexual maturity. Testicular weight increased gradually until 4 weeks and abruptly increased from 5 weeks of age onwards. The plasma concentrations of LH and ir-inhibin increased significantly at 5 weeks of age, and the plasma concentration of testosterone increased significantly at 6 weeks of age. Pituitary contents of LH showed a steady increase until 6 weeks of age and then abruptly increased at 7 weeks of age. Coincident to the increase in plasma testosterone, the testicular contents of testosterone significantly increased from 5 weeks through sexual maturity.Immunohistochemically, localization of the inhibin/activin α, βA and βB subunts was found in the Sertoli and Leydig cells at all ages of development from one week of age to sexual maturity. These results suggest that Sertoli and Leydig cells are the major source of inhibin secretion during development in male Japanese quail. Key words: Inhibin, Japanese quail (Coturnix japonica), Luteinizing hormone (LH), Testes, Testosterone (J. Reprod. Dev. 54: [100][101][102][103][104][105][106] 2008) nhibins and activins are growth and differentiation factors that have been localized in both the reproductive and non-reproductive organs. They exert their effects through both endocrine and local (autocrine/paracrine) mechanisms [1]. Inhibins and activins are structurally related dimeric gonadal proteins with the ability to regulate follicle-stimulating hormone (FSH) secretion from the pituitary glands [2,3]. Inhibin consists of an α subunit linked by a disulfide bridge to one of the 2 highly homologous β subunits (βA and βB) to form inhibin A (α and βA) or inhibin B (α and βB) [4]. In mammalian species, apart from their action on FSH secretion, the inhibins and activins have been shown to exert paracrine/autocrine effects within the gonads [5][6][7][8] and other tissues [9] and have been proposed to have an important paracrine function during testes development [10,11]. In the male, inhibin is produced in the testis, principally by Sertoli cells. There are temporal changes in inhibin expression and secretion with the changing role of the Sertoli cell in immature and adult testes. Variations in inhibins production among species reflect the different patterns of maturation [11][12][13].In avian species, studies have confirmed a mammalian-type endocrine role for inhibins [14][15][16][17]; however, the autocrine/paracrine roles of inhibins and activins in the gonads are still being defined. The profiles of plasm...

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The endocrine control by luteinizing hormone of testosterone secretion from the testis of the Japanese quail

Cited by 45 publications

References 39 publications

Concentrations of Luteinizing Hormone in the Plasma of Hemicastrated Cockerels

Concentrations of Luteinizing Hormone in the Plasma of Hemicastrated Cockerels

Developmental changes in immunoreactive inhibin and FSH in plasma of chickens from hatch to sexual maturity

Secretion of Inhibin in Male Japanese Quail (<i>Coturnix japonica</i>) from One Week of Age to Sexual Maturity

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