The end of the tour de force of the corpus luteum in mares

Ginther, O.J.

doi:10.1016/j.theriogenology.2011.10.026

Cited by 10 publications

(13 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…An increase in luteal blood flow appears to be a universal phenomenon in mares whether luteolysis is natural or induced [34,36,[43][44][45][46]. A transient increase in luteal blood flow between 1 and 3 hours was also seen in the present jennies.…”

Section: Discussionsupporting

confidence: 55%

See 1 more Smart Citation

Color Doppler provides a reliable and rapid means of monitoring luteolysis in female donkeys

et al. 2015

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 55%

“…However, in the mare, luteal blood flow does not increase during early luteolysis, and plasma progesterone decreases before significant reductions in luteal blood flow are detected [32,35,36]. Moreover, a reduction in angiogenesis in the CL of mares has been described during the late luteal phase induced by PGF2a [15].…”

Section: Introductionmentioning

confidence: 99%

Color Doppler provides a reliable and rapid means of monitoring luteolysis in female donkeys

et al. 2015

View full text Add to dashboard Cite

“…Mares are reported to have a lower rate of PGF2α catabolism which increases the half-life of PGF2α compared to cows (Weems et al, 2006). Thus, the systemic luteolytic dose of PGF2α in mares is one fifth that of cows (Ginther, 2012). In cattle, rapid metabolism of PGF2α by the lungs suggests that the uterine trauma caused by external procedures like transrectal uterine manipulation or more uterine invasive techniques such as EB, may not affect the CL lifespan.…”

Section: Introductionmentioning

confidence: 99%

“…In cows, in the normal cycle endometrial PGF2α is transported by vascular countercurrent exchange from the uterine vein into the ovarian artery ipsilateral to the ovary that contains the CL and once there induces luteolysis (Ginther, 2012). Thus, the uterine horn where the biopsy is taken from, might affect the entry of PGF2α into the CL.…”

Section: Introductionmentioning

confidence: 99%

63 Effect of Endometrial Biopsy on Uterine Health of Tropically Adapted Beef Cattle

Ramirez-Garzon

Satake

Lyons

et al. 2017

Reprod. Fertil. Dev.

View full text Add to dashboard Cite

In cattle, early embryonic loss during the first two to three weeks after fertilisation is recognised as the major cause of reproductive failure, with consequent significant impacts on business performance of beef and dairy farms. Inadequate endometrial receptivity is considered an important cause of early embryonic mortality in cattle. A pilot experiment was conducted to compare the outcome of performing different endometrial sampling procedures in tropically adapted (Bos indicus x Bos taurus) heifers, and to select the most suitable method to collect samples for investigation of endometrial gene expression. Endometrial biopsy (EB) using a biopsy device with a diameter similar to an artificial insemination gun (10366L Karl Storz®, Germany) was found to be the most reliable method of collecting endometrial samples in these heifers, with the samples recovered yielding a mean concentration of RNA of 72.9 ±39.3 ng/µl and mean RNA integrity number (RIN) of 7.3 ±1.1.To assess the likely safety of conducting EB in cattle a systematic review of published information assessing the impact of EB on subsequent pregnancy rates was conducted. Using the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) protocol, online searches identified 1164 possible studies. After applying the exclusion criteria, six studies allowed the comparison of pregnancy rates between sampled (n= 1,208) and non-sampled cows (n=2,393). The results showed that EB can be performed before breeding without adversely affecting the likelihood of cows becoming pregnant.A major objective of the research was to determine whether EB and evaluation of endometrial gene expression could be used to identify tropically adapted embryo transfer (ET) recipients more likely to become pregnant. Three potential EB scenarios were investigated, 1) EB on Day 7 of the oestrous cycle prior to the cycle when ET would be performed, 2) EB on Day 4 of the oestrous cycle in which ET would be performed i.e. EB 3 days before ET, and 3) EB on the same day when ET would be performed.The first study assessed the morphological and inflammatory changes induced by endometrial biopsy. Pre-synchronised heifers underwent EB from the horn ipsilateral to the corpus luteum (CL) either at Day 7 of the previous cycle (Group 1 n=10) followed by administration of a luteolytic dose of prostaglandin F2α or at Day 4 (Group 2, n=7) of the present cycle. All heifers were slaughtered on Day 7 of the present cycle. The site of EB was visually evident in 40% (4/10) of Group 1 and 42% (3/7) of Group 2 heifers. Histological assessment revealed no evidence of changes indicative of endometritis in either the biopsied or non-biopsied horns in both groups. The histological iii changes observed included mild mononuclear infiltration of the epithelium and mild vascular changes associated with haemorrhage and congestion.Initial investigation of the endometrial expression of the pro-inflammatory cytokine IL1β and wound healing cytokine TGFβ genes found no significant difference betwe...

show abstract

“…Prolactin increases during luteolysis during the IOI and during the expected time of luteolysis in mares with PCL [11]. However, a role for prolactin in PCL should be further considered, owing to the reports that prolactin in mares is involved in reproductive seasonality [18], prolactin activity increases during luteolysis [27], pulses of prolactin and PGFM are synchronized [27,28], and PGF2a stimulates prolactin rather than prolactin stimulating PGF2a [29].…”

Section: Introductionmentioning

confidence: 99%

Hormonal, luteal, and follicular changes during initiation of persistent corpus luteum in mares

2015

Self Cite

View full text Add to dashboard Cite

The end of the tour de force of the corpus luteum in mares

Cited by 10 publications

References 38 publications

Color Doppler provides a reliable and rapid means of monitoring luteolysis in female donkeys

Color Doppler provides a reliable and rapid means of monitoring luteolysis in female donkeys

63 Effect of Endometrial Biopsy on Uterine Health of Tropically Adapted Beef Cattle

Hormonal, luteal, and follicular changes during initiation of persistent corpus luteum in mares

Contact Info

Product

Resources

About