The Emergence of Novel-Coronavirus and its Replication Cycle - An Overview

Iqbal, Hafiz M.N.; Romero‐Castillo, Kenya D.; Bilal, Muhammad; Parra‐Saldívar, Roberto

doi:10.22207/jpam.14.1.03

Cited by 37 publications

(7 citation statements)

References 3 publications

(3 reference statements)

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“…The third pandemic, caused by COVID-19, also belong to coronaviruses family, which caused severe acute respiratory syndrome, alarmed global public health authorities to take some timely measures to control the pandemic switch (Iqbal et al, 2020;Morens et al, 2020). Seventeen years later, similar cases or even more severe situation appeared in the form of the pandemic of COVID-19 prevalence.…”

Section: Coronaviruses and Respiratory Syndromesbeyond The Common Coldmentioning

confidence: 99%

Coronaviruses and COVID-19 – Complications and Lessons Learned for the Future

Bilal¹,

Khan²,

Nazir³

et al. 2020

J. Pure Appl. Microbiol.

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Despite the earlier two Coronavirus outbreaks, this appearance of the third Coronavirus outbreak has brought several complications and now emerged as a human-health related pandemic issue. The wide geographical spread and transmissibility of newly emerged novel-Coronavirus (2019-nCoV) and severity of coronavirus disease 2019 (COVID-19) raised serious concerns about the future trajectory of the 2019-nCoV/COVID-19 outbreak. Herein, we have briefly covered some important aspects of the 2019-nCoV/COVID-19 outbreak to highlight the need to learn lessons for a safer future. First, an epidemiological comparison of respiratory viral infections with particular reference to 2019-nCoV is given with relevant examples. Following that, considering the earlier two Coronavirus outbreaks, the emergence of another new 2019-nCoV is given. Finally, the lesson learned, so far, and key concerns for pandemic impact assessment at large and COVID-19, in particular, are discussed for future considerations.

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Section: Coronaviruses and Respiratory Syndromesbeyond The Common Coldmentioning

confidence: 99%

Coronaviruses and COVID-19 – Complications and Lessons Learned for the Future

Bilal¹,

Khan²,

Nazir³

et al. 2020

J. Pure Appl. Microbiol.

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“…Different types of non-pharmaceutical interventions are taken and suggested to manage the COVID-19 effectively because there are no licensed authentic vaccines or coronavirus antivirals are found, one of the effective managements is seen i.e., lockdown 7 . The pessimistic view of this lockdowm is that it effects the whole world economy particularly transportation because the people are in quarantine state.…”

Section: Introductionmentioning

confidence: 99%

Correlation Between Temperature and COVID-19 (Suspected, Confirmed and Death) Cases based on Machine Learning Analysis

Siddiqui¹,

Morales-Menéndez²,

Gupta³

et al. 2020

J. Pure Appl. Microbiol.

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Currently, the whole world is struggling with the biggest health problem COVID-19 name coined by the World Health Organization (WHO). This was raised from China in December 2019. This pandemic is going to change the world. Due to its communicable nature, it is contagious to both medically and economically. Though different contributing factors are not known yet. Herein, an effort has been made to find the correlation between temperature and different cases situation (suspected, confirmed, and death cases). For a said purpose, k-means clustering-based machine learning method has been employed on the data set from different regions of China, which has been obtained from the WHO. The novelty of this work is that we have included the temperature field in the original WHO data set and further explore the trends. The trends show the effect of temperature on each region in three different perspectives of COVID-19 – suspected, confirmed and death.

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“…Direct membrane attachment or fusion occurs with the host receptor by undergoing proteolytic cleavage at the S1/S2 boundary, known to be penetration [25,26]. Then, in the host cell cytoplasm, the RNA is released, then RNA moves towards the nucleus and inside the nucleus; biosynthesis occurs by following transcription, translation, protein synthesis [27]. The synthesized protein moves through the endoplasmic reticulum, and the Golgi apparatus gets matured and liberated back to the body [28].…”

Section: Etiopathogenesis Of Sars-cov-2mentioning

confidence: 99%

Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic

Asdaq¹,

Ikbal

Sahu

et al. 2021

Nanomaterials

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The SARS-CoV-2 outbreak is the COVID-19 disease, which has caused massive health devastation, prompting the World Health Organization to declare a worldwide health emergency. The corona virus infected millions of people worldwide, and many died as a result of a lack of particular medications. The current emergency necessitates extensive therapy in order to stop the spread of the coronavirus. There are various vaccinations available, but no validated COVID-19 treatments. Since its outbreak, many therapeutics have been tested, including the use of repurposed medications, nucleoside inhibitors, protease inhibitors, broad spectrum antivirals, convalescence plasma therapies, immune-modulators, and monoclonal antibodies. However, these approaches have not yielded any outcomes and are mostly used to alleviate symptoms associated with potentially fatal adverse drug reactions. Nanoparticles, on the other hand, may prove to be an effective treatment for COVID-19. They can be designed to boost the efficacy of currently available antiviral medications or to trigger a rapid immune response against COVID-19. In the last decade, there has been significant progress in nanotechnology. This review focuses on the virus’s basic structure, pathogenesis, and current treatment options for COVID-19. This study addresses nanotechnology and its applications in diagnosis, prevention, treatment, and targeted vaccine delivery, laying the groundwork for a successful pandemic fight.

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The Emergence of Novel-Coronavirus and its Replication Cycle - An Overview

Cited by 37 publications

References 3 publications

Coronaviruses and COVID-19 – Complications and Lessons Learned for the Future

Coronaviruses and COVID-19 – Complications and Lessons Learned for the Future

Correlation Between Temperature and COVID-19 (Suspected, Confirmed and Death) Cases based on Machine Learning Analysis

Nanotechnology Integration for SARS-CoV-2 Diagnosis and Treatment: An Approach to Preventing Pandemic

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