The Effort-reward Imbalance work-stress model and daytime salivary cortisol and dehydroepiandrosterone (DHEA) among Japanese women

Abstract

We examined the influence of work-related effort–reward imbalance and overcommitment to work (OC), as derived from Siegrist's Effort–Reward Imbalance (ERI) model, on the hypothalamic–pituitary–adrenocortical (HPA) axis. We hypothesized that, among healthy workers, both cortisol and dehydroepiandrosterone (DHEA) secretion would be increased by effort–reward imbalance and OC and, as a result, cortisol-to-DHEA ratio (C/D ratio) would not differ by effort–reward imbalance or OC. The subjects were 115 healthy female nursery school teachers. Salivary cortisol, DHEA, and C/D ratio were used as indexes of HPA activity. Mixed-model analyses of variance revealed that neither the interaction between the ERI model indicators (i.e., effort, reward, effort-to-reward ratio, and OC) and the series of measurement times (9:00, 12:00, and 15:00) nor the main effect of the ERI model indicators was significant for daytime salivary cortisol, DHEA, or C/D ratio. Multiple linear regression analyses indicated that none of the ERI model indicators was significantly associated with area under the curve of daytime salivary cortisol, DHEA, or C/D ratio. We found that effort, reward, effort–reward imbalance, and OC had little influence on daytime variation patterns, levels, or amounts of salivary HPA-axis-related hormones. Thus, our hypotheses were not supported.

Effort–reward imbalance in police work: associations with the cortisol awakening response

“…Other studies have found contrary results reporting no significant associations between ERI and lowered awakening cortisol (Hanson et al 2000; Harris et al 2007; Marchand et al 2016; Ota et al 2014). Steptoe et al (2004) did not find a significant association of dysregulated CAR with ERI.…”

Psychological job strain, social support at work and daytime secretion of dehydroepiandrosterone (DHEA) in healthy female employees: cross-sectional analyses

“…We cross-sectionally analysed the baseline dataset of a prospective cohort study which was conducted to clarify the relationship between work-related psychosocial factors and musculoskeletal disorders in nursery school teachers 41 . Table 1 presents general characteristics (age, employment status, current smoking, menstruation irregularity, ovulatory phase and health disorders), job strain and social support scores and logarithmic (log)-transformed area under the curve with respect to ground (AUC G ) 42 of salivary DHEA, cortisol and C/D ratio of the subjects.…”

“…This is concordant with the existing evidence 38 40 . We reported that effort–reward imbalance and overcommitment to work, as derived from the Effort–Reward Imbalance (ERI) model 47 , were not associated with daytime cortisol or DHEA secretion in the same subjects 41 . As previously mentioned, existing research presents contradictory findings on the associations between the DCS model dimensions and daytime cortisol secretion 23 24 25 26 27 28 29 30 31 32 33 34 .…”

“…Finally, we did not collect information regarding alcohol consumption, diet, sleep (awakening time, sleep duration, sleep quality, etc. ), education level or marital status, all of which could possibly affect the HPA activity and DHEA secretion 41 50 .…”

Szteroidok: A glükokortikoidok élettani és gyógyszertani hatásai

“…A DHEA szulfatálódásának, azaz a DHEAS termelődésének kizárólagos helye a szervezetben ez a réteg. A DHEA anti-GC hatása miatt számos tanulmány szerint a kortizol/DHEA arányt célszerűbb vizsgálni pusztán a GC-szintnél [6].…”