The Efficacy of Partial Liquid Ventilation in Lung Protection During Hypotension and Cardiac Arrest: Preliminary Study of Lung Transplantation Using Non–heart–beating Donors

Yoshida, Shigetoshi; Sekine, Yasuo; Shinozuka, Norihiro; Satoh, Jiro; Yasufuku, Kazuhiro; Iwata, Takekazu; Saitoh, Yukio; Fujisawa, Takehiko

doi:10.1016/j.healun.2004.03.019

Cited by 12 publications

(12 citation statements)

References 24 publications

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“…In a pig model, Rega et al 20 found better tolerance to ischemia after giving nebulized N-acetylcysteine to the donor before death or immediately after arrest. Yoshida et al 21 reported recently a protective effect of partial liquid ventilation during hypotension in rabbits.…”

Section: Discussionmentioning

confidence: 97%

Results of Clinical Lung Transplant From Uncontrolled Non-Heart-Beating Donors

Antonio

Marcos

Laporta

et al. 2007

The Journal of Heart and Lung Transplantation

145

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Section: Discussionmentioning

confidence: 97%

Results of Clinical Lung Transplant From Uncontrolled Non-Heart-Beating Donors

Antonio

Marcos

Laporta

et al. 2007

The Journal of Heart and Lung Transplantation

145

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“…Using rabbit lungs, they maintained hypotension at <50 mmHg for 1 h followed by 2-h cardiac arrest. Histologic evaluation after perfusion of the preservation solution revealed that alveolar structure was damaged significantly less and cell infiltration was milder in the PLV groups than in the control group (45). Tissue IL-8 in the PLV groups remained at baseline concentrations during the study period.…”

Section: Proof Of Concept and Experimental Backgroundmentioning

confidence: 85%

“…Tissue IL-8 in the PLV groups remained at baseline concentrations during the study period. They concluded that PLV suppresses lung injury when compared with gas-controlled ventilation (45).…”

Section: Proof Of Concept and Experimental Backgroundmentioning

confidence: 99%

Donors after cardiocirculatory death and lung transplantation

İnci

2017

J. Thorac. Dis.

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Abstract:The number of patients actively awaiting lung transplantation (LTx) is more than the number of suitable donor lungs. The percentage of lung retrieval rate is lower when compared to other solid organs.The use of lungs from donation after cardiocirculatory death (DCD) donors is one of the options to avoid organ shortage in LTx. After extensive experimental research, clinical application of DCD donation is becoming wider. The results from most of the centers show at least equal survival rate compared to donors from brain death. This review paper will summarize experimental background and clinical experience from DCD donors.

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“…Ten articles were properly describing induction of hypothermia (Shaffer et al, 1984;Forman et al, 1986;Harris et al, 2001;Hong et al, 2002;Castren et al, 2010;Nadeau et al, 2013Nadeau et al, , 2014Kumar et al, 2014;Hutin et al, 2015), and two articles the induction of core rewarming through PFC-associated methods (Dickson et al, 2001;Tobias et al, 2001). Other articles focused on the use of liquid ventilation after cardiac arrest (n = 8), (Yoshida et al, 2005;Staffey et al, 2008;Riter et al, 2009;Albaghdadi et al, 2011;Chenoune et al, 2011;Darbera et al, 2013;Tissier et al, 2014;Kohlhauer et al, 2015) during coronary artery occlusion (CAO, n = 5) (Tissier et al, 2007(Tissier et al, , 2009(Tissier et al, , 2013Chenoune et al, 2010;Darbera et al, 2012) or for lung preservation (n = 2) (Yang et al, 2005;Jiang et al, 2006). Two additional articles evaluated the hemodynamic tolerance of TLV Jiang et al, 2011).…”

Section: Resultsmentioning

confidence: 99%

Liquid Ventilation for the Induction of Ultrafast Hypothermia in Resuscitation Sciences: A Review

Kohlhauer

Berdeaux

Kerber

et al. 2016

Therapeutic Hypothermia and Temperature Management

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Liquid ventilation was initially proposed for lung lavage and respiratory support. More recently, it was also investigated as an experimental strategy for ultrafast cooling or organ preservation during ischemic disorders. The goal of this article is to identify and review the studies that investigated liquid ventilation in the field of resuscitation sciences. An exhaustive analysis of the literature was performed using the Medline database up to 15th September 2015. Articles were selected according to their relevance. All articles focusing on respiratory support were excluded. On the basis of 76 retrieved studies from the Medline database, 29 were included in this review. All studies were experimental reports and most of them investigated the cooling properties of liquid ventilation in animal models of experimental cardiac arrest or coronary artery occlusion in rabbits or pigs. Animal studies demonstrated a wide range of potential applications of total liquid ventilation in resuscitation sciences. This strategy is able to provide ultrafast cooling, independent of the body weight. In animal models of cardiopulmonary resuscitation, it was shown to provide potent benefits widely linked to cooling rapidity.

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The Efficacy of Partial Liquid Ventilation in Lung Protection During Hypotension and Cardiac Arrest: Preliminary Study of Lung Transplantation Using Non–heart–beating Donors

Cited by 12 publications

References 24 publications

Results of Clinical Lung Transplant From Uncontrolled Non-Heart-Beating Donors

Results of Clinical Lung Transplant From Uncontrolled Non-Heart-Beating Donors

Donors after cardiocirculatory death and lung transplantation

Liquid Ventilation for the Induction of Ultrafast Hypothermia in Resuscitation Sciences: A Review

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