The efficacy of gonioscopy-assisted transluminal trabeculectomy combined with phacoemulsification

Bozkurt, Ercüment; Yenihayat, Fatih; Olgun, Ali; Yazıcı, Ahmet; Şahbaz, İbrahim

doi:10.1007/s10792-020-01550-x

Cited by 10 publications

(3 citation statements)

References 23 publications

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“…Since IOP variations can occur on account of phacoemulsification alone,21,22 it is important to compare IOP decreases obtained by isolated GATT procedure and PHACO-GATT. Bozkurt et al23 revealed more pronounced reduction in IOP after stand-alone GATT compared with GATT associated with cataract extraction. However, the higher baseline IOP in the isolated GATT group and a higher mean age in the combined surgery group may in part explain the difference found in their study.…”

Section: Discussionmentioning

confidence: 97%

Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Faria

Costa

Melillo

et al. 2022

Journal of Glaucoma

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Précis: Our results suggest gonioscopy-assisted transluminal trabeculotomy (GATT) as an effective and safe option for the surgical management of open-angle glaucoma (OAG). Older age was the only risk factor for failure in our analysis. Purpose: To report 12-month clinical outcomes, safety profile and success predictors of GATT in patients with OAG. Patients and Methods: A retrospective study of patients (18 y old and above) with medically uncontrolled OAG who underwent GATT as a solo procedure or combined with phacoemulsification (PHACO-GATT) between January 2018 and January 2020. Success at 12 months (primary outcome) was defined as intraocular pressure (IOP) <15 mm Hg, with an IOP reduction of at least 20%, OR a reduction of at least 2 glaucoma medications, compared with baseline. Secondary outcomes were success predictors and safety parameters. Results: A total of 73 eyes (GATT=38; PHACO-GATT=35) from 58 patients with a mean age of 54.8±11.6 years were included. Overall, after 12 months of follow-up, the mean IOP was reduced from 24.9±8.5 to 12.1±2.1 mm Hg (P<0.001). The mean number of glaucoma medications was reduced from 3.5±0.7 to 1.2±1.2 (P<0.001). The success rate was 87% at 12 months, with no significant differences between GATT (85%) and PHACO-GATT (91%) eyes (P=0.330). Age was the only factor significantly associated with surgical success (hazard ratio=1.35; P=0.012; after adjusting for preoperative IOP and number of glaucoma medications). Patients older than 60 years had a significant greater chance of failure (hazard ratio=10.96; P=0.026) compared with those younger than 60 years. The most common postoperative complication was transient hyphema (39%; median duration, 5 d). No sight-threatening adverse event was documented. Conclusions: GATT was effective and safe at lowering IOP with or without cataract extraction in OAG. Patients 60 years or older had a higher risk of failure compared with those younger in age.

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Section: Discussionmentioning

confidence: 97%

Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Faria

Costa

Melillo

et al. 2022

Journal of Glaucoma

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“…In the context of POAG, a global success rate between 49% and 83.8% has been described. [69][70][71][72][73][74][75] Grover et al demonstrated that the procedure resulted in a mean IOP reduction of 7.7 ± 6.2 mm Hg (30% reduction) at 6 months and 11.1 ± 6.1 mm Hg (39% reduction) at 12 months. The use of glaucoma medications also decreased significantly, by 0.9 ± 1.3 drops and 1.1 ± 1.8 drops at months 6 and 12, respectively.…”

Section: Gonioscopy-assisted Transluminal Trabeculotomymentioning

confidence: 99%

“…GATT has shown effectiveness in treating various subtypes of glaucoma. In the context of POAG, a global success rate between 49% and 83.8% has been described 69–75 . Grover et al demonstrated that the procedure resulted in a mean IOP reduction of 7.7 ± 6.2 mm Hg (30% reduction) at 6 months and 11.1 ± 6.1 mm Hg (39% reduction) at 12 months.…”

Section: Non-bleb Forming Trabecular Meshwork Canal Cleaving Approachesmentioning

confidence: 99%

Minimally Invasive Glaucoma Surgery

Gallo Afflitto,

Swaminathan

2023

International Ophthalmology Clinics

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Therapie eines Sekundärglaukoms nach intravitrealer Anti-VEGF-Therapie mit dem XEN®-Gel-Stent und Mitomycin C

Bedar

Kellner

2020

Ophthalmologe

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The efficacy of gonioscopy-assisted transluminal trabeculectomy combined with phacoemulsification

Cited by 10 publications

References 23 publications

Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Minimally Invasive Glaucoma Surgery

Therapie eines Sekundärglaukoms nach intravitrealer Anti-VEGF-Therapie mit dem XEN®-Gel-Stent und Mitomycin C

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