The efficacy of artificial dermis combined with continuous vacuum sealing drainage in deep neck multiple spaces infection treatment

Abstract

Deep neck abscesses are dangerous. Artificial dermis combined with seal negative pressure drainage is a new technique for treating refractory wounds. To compare the efficacy of vacuum sealing drainage (VSD) with that of traditional incision drainage approaches for treating deep neck multiple spaces infections. This retrospective analysis includes patient data from our hospital collected from January 2010 to March 2020. A total of 20 cases were identified. Based on the treatment methods, the patients were divided into the VSD group and the traditional group. Inflammation indicators (white blood count, WBC), duration of antibiotic use, hospitalization time, doctors’ workload (frequency of dressing changes) and treatment cost were analyzed and compared between the two groups. Of the 20 patients, 11 patients underwent treatment with VSD, while the other 9 underwent traditional treatment. All patients were cured after treatment. Compared with the traditional group, the VSD group had a slower decline in the inflammation index, shorter duration of antibiotic use, shorter hospital stay, and lower doctor workloads ( P < .001). There was no significant difference in treatment cost between the two groups ( P > .05). VSD technology can markedly improve the therapeutic effect of deep neck multiple spaces infection. This treatment method can be used to rapidly control infections and is valuable in the clinic ( P > .05).

A Five-Year Retrospective Study of 746 Cases with Maxillofacial Space Infection in Western China

“…Several studies have proven that the vacuum sealing drainage (VSD) technique can shorten the hospitalization time of patients with severe space infection in the head and neck. [27][28][29][30] However, because simple negative pressure cannot solve problems such as the formation of a secondary pus cavity, further studies are needed to verify the clinical effect of this technique.…”

Evaluation of injectable platelet-rich fibrin produced by a simple twice-centrifugation method combined with vacuum sealing drainage technology in the treatment of chronic refractory wounds

“…The pathogenesis of refractory wounds is very complex, including a series of cascade reactions such as tissue ischemia and hypoxia, growth factor deficiency, apoptosis, and oxidative stress ( Lu et al, 2021 ). In addition, the long-term unhealing of refractory wounds will lead to the aging of the granulation tissue of the wound, the formation of biofilms and fibrous plates, and the reduction of the expression of various growth factors, further delaying the wound healing process, and forming a vicious circle, which can lead to malignant transformation ( Gu et al, 2021 ). On the other hand, long-term non-healing of refractory wounds will lead to wound granulation tissue aging, the formation of biofilm and fiberboard, the expression of various growth factors reduced, further delay the process of wound healing, and even lead to malignant transformation ( Lu et al, 2021 ).…”

“…VSD is a common wound repair method currently in practice. Its principle is to use porous foam material and a biological semi-permeable membrane to turn open wounds into closed wounds, carry out continuous or intermittent attraction, and timely remove wound secretions and necrotic tissue fragments while increasing blood flow and reducing local tissue edema ( Gu et al, 2021 ). Duan et al (2019) reported that negative pressure wound treatment could effectively control infection, reduce the positive rate of bacteria in wound, shorten the length of hospital stay, and improve wound healing.…”

The Efficacy of Pyogenic Cavity Aerobic Therapy with Negative Pressure Drainage in the Treatment of Deep Neck Space Infections

“…A DNSI may also lead to upper respiratory tract obstruction, eventually causing serious consequences or even death. 9 Therefore, early incision and drainage should be performed if the diameter of an abscess is confirmed by imaging to be >2.5 cm. 10 Cramer et al 4 reported that delay in surgical drainage of deep neck abscess was associated with increased abscess-specific morbidity and mortality in their study.…”