The effects of whole-body vibration training and vitamin D supplementation on muscle strength, muscle mass, and bone density in institutionalized elderly women: A 6-month randomized, controlled trial

Abstract

Sarcopenia and osteoporosis represent a growing public health problem. We studied the potential benefit of whole-body vibration (WBV) training given a conventional or a high dose of daily vitamin D supplementation in improving strength, muscle mass, and bone density in postmenopausal women. In a 2 Â 2 factorial-design trial, 113 institutionalized elderly females aged over 70 years (mean age 79.6 years) were randomly assigned either to a WBV or a no-training group, receiving either a conventional dose (880 IU/day) or a high dose (1600 IU/day) of vitamin D 3 . The primary aim was to determine the effects of 6 months of WBV and/or vitamin D supplementation on isometric and dynamic strength, leg muscle mass, and hip bone mineral density (BMD). Additionally, the increase in 25-hydroxyvitamin D [25(OH)D] levels between conventional and high-dose supplementation was compared. After 6 months of treatment, dynamic muscle strength, hip BMD, and vitamin D serum levels improved significantly in all groups, whereas isometric strength and muscle mass did not change. When compared with no training, the WBV program did not result in additional improvements. When compared with 880 IU, a high dose of 1600 IU of vitamin D did result in higher serum vitamin D levels but did not result in additional improvements. In institutionalized women older than 70 years, the WBV training protocol tested is not more efficient in enhancing muscle mass, strength, and hip BMD compared with vitamin D supplementation. A higher dose of 1600 IU of vitamin D does not provide additional musculoskeletal benefit in this population compared with conventional doses. ß

Canabis-induced Moto-cognitive Dysfunction in Wistar Rats: Ameliorative Efficacy of Nigella Sativa

“…(16) In another study of 710 post-menopausal women, using low-magnitude high-frequency vibration (LMHFV) for 18 months, the author stated that the BMD of the hip and spine showed a positive trend in the vibration group compared to the controls (mean between-group difference 1.43% for femoral neck, 1.12% for spine) (22). The author concluded that the effect was not statistically significant after Bonferroni adjustment.…”

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“…However, the most recent research of Gómez-Cabello et al (27) did not confirm the beneficial effects of WBV on the anabolic activity of bone tissue. Verschueren et al (68), on the other hand, found a significant 0.75% increase in total-hip BMD while Lai et al (36) noted a 2.032% increase in lumbar BMD after a WBV program. It has been emphasized, however, that a similar effect was obtained in women with vitamin D supplementation (68) or balance training (62).…”

“…The density of the hip bone (68), lumbar spine (36), or the tibia (62) was assessed with dual-energy X-ray absorptiometry and/or peripheral quantitative computed tomography (36,62,68). There were several differences between training programs: both vertical (66) and side-alternating WBV (62) were used; training duration ranged from 11 weeks (27) to 9 months (62); uniform vibration parameters were applied (66) or, if needed, changed according to overload principle (62,68). Study participants most often performed static and/or dynamic exercises, including squats and standing (27,62,68).…”

“…There were several differences between training programs: both vertical (66) and side-alternating WBV (62) were used; training duration ranged from 11 weeks (27) to 9 months (62); uniform vibration parameters were applied (66) or, if needed, changed according to overload principle (62,68). Study participants most often performed static and/or dynamic exercises, including squats and standing (27,62,68). The importance of correct training program selection (frequency of exposure) was emphasized by Turner et al (66); only one among WBV training protocols used in their study led to a meaningful change in bone turnover.…”

Calcio como agente terapéutico en osteoporosis

“…En adultos sanos la suplementación con Vitamina D no previene Osteoporosis, pero en los ancianos mantener adecuadas reservas de vitamina D combinado con ingesta sufi ciente de calcio es una efectiva estrategia para prevenir fracturas de cadera. (290)(291)(292)(293)(294)(295)(296)(297)(298)(299)(300).…”