The Effects of UVA Irradiation on Depigmented Sites in the Skin of the Hairless Dog

Abstract

UVA irradiation had deleterious effects on the QRL-treated sites and caused a recurrence of spotty pigmentation. Hairless dogs are useful laboratory animals for evaluating gross and histopathological changes in pigmented lesions treated with QRL irradiation.

Hairless Descendants of Mexican Hairless Dogs: An Experimental Model for Studying Hypertrophic Scars

“…The repaired skin shared some of the characteristics of human hypertrophic scars, including a thickening of the stratum corneum and epidermis. As reported in experimental laser treatment, 23,24 microcomedones accompanied by sebaceous glands were observed during the wound healing process in hairless dogs.…”

“…20 Therefore, hairless dogs have been used for investigating skin grafts, 20 wound dressings, 21 burn wound healing, 22 and laser surgery. 23,24 During these investigations, I have encountered pigmented hypertrophic scar-like lesions on donor sites in hairless dogs.…”