The effects of topical levobupivacaine on morbidity in pediatric tonsillectomy patients

Does preincisional injection of levobupivacaine with epinephrine have any benefits for children undergoing tonsillectomy? An intraindividual evaluation

“…The common outcome of our study and these two studies was that levobupivacaine had beneficial effects on post-tonsillectomy pain relief. The reported duration of this relief varies between 16 to 24 h in the literature [7,10]. In our study the significant pain relieving effect was observed for the first 16 h, as in Karaaslan et al's study.…”

“…Different surgical techniques, several analgesic medications through different routes have been tried to establish an effective and safe pain control [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]23,[26][27][28].…”

“…We encountered only 2 studies demonstrating the effects of levobupivacaine on post-tonsillectomy pain in the literature [7,10]. Karaaslan et al reported that post-tonsillectomy injection of both levobupivacaine and levobupivacaine with magnesium reduced the pain scores and magnesium also contributed to decrease additional analgesic consumption [7].…”

“…Yilmaz et al also used levobupivacaine after tonsillectomy, but they preferred topical administration through compression with levobupivacaine soaked swabs. They reported that administration of levobupivacaine was beneficial to postoperative pain relief [10]. Differently from these two studies, we added 1/200.000 epinephrine to levobupivacaine and we injected LE before onset of tonsillectomy.…”

“…Differently from these two studies, we added 1/200.000 epinephrine to levobupivacaine and we injected LE before onset of tonsillectomy. We used contralateral side of the study as the control group, whereas an interindividual study design was used in the previous two studies [7,10]. The common outcome of our study and these two studies was that levobupivacaine had beneficial effects on post-tonsillectomy pain relief.…”