The Effects of Rice Husk Liquid Smoke in Porphyromonas gingivalis-Induced Periodontitis

Budhy, Theresia Indah; Arundina, Ira; Surboyo, Meircurius Dwi Condro; Halimah, Anisa Nur

doi:10.1055/s-0041-1727554

Cited by 14 publications

(20 citation statements)

References 32 publications

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“…7 The liquid smoke rice husk showed the MIC at the concentration of 10% and MBC at concentration of 12.5% to Porphyromonas gingivalis . 7 16 The large decrease in the number of colonies occurred due to the phenolic compounds carried by the nanoparticles working effectively on the target cells. The content of phenolic compounds in nLSRH indicates the presence of molecular activity in it in the form of proton distribution assisted by protonophores across the hydrophobic core of the membrane.…”

Section: Discussionmentioning

confidence: 99%

Nanoparticles of Liquid Smoke Rice Husk Inhibit Porphyromonas gingivalis

et al. 2022

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Objective Utilization of liquid smoke rice husk can be used as an alternative treatment because of the antimicrobial properties. Advances in drug delivery systems are increasingly developing to increase the bioavailability of drugs and reduce the side effects of these drugs, namely nanoparticles. In this study, nanoparticles of liquid smoke rice husk (nLSRH) were tested the antimicrobial against Porphyromonas gingivalis. Materials and Method This type of research is an experimental in vitro laboratory using Porphyromonas gingivalis culture. nLSRH contained liquid smoke rice husk concentration of 1, 2.5, 5, 7.5, 10, 12.5, 15, and 17.5%. The antibacterial was performed using the dilution methods. Results The nLRSH concentration of 1% showed clearest medium. The highest number of colonies Porphyromonas gingivalis was observed at nLSRH concentration of 1% (40.3 colony-forming unit [CFU]) and decreased at a concentration of 2.5% (11.3 CFU); other concentration or no bacterial colony growth was found. The nLSRH concentration of 2.5% can be determined as the minimum inhibitory concentration and nLSRH concentration of 5% can be determined as the minimum bactericidal concentration. Conclusion nLSRH have antimicrobial activity against Porphyromonas gingivalis. This finding able to drive the next research to develop nLSRH as gingival and periodontitis disease is caused by Porphyromonas gingivalis.

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Section: Discussionmentioning

confidence: 99%

Nanoparticles of Liquid Smoke Rice Husk Inhibit Porphyromonas gingivalis

et al. 2022

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“…26 These changes in oral microbiota can be correlated with oral and general manifestations to some extent. Altered species which have been reported to have a positive correlation with periodontitis include P. gingivalis, T. forsythia, T. denticola, P. intermedia, phyla bacteroidetes, Prevotella salivae, A. actinomycetemcomitans, P. micra, and C. rectus 25,[55][56][57][58][59][60][61] . Whereas Neisseria and Bifidobacteria have a negative correlation with periodontitis.…”

Section: Discussionmentioning

confidence: 99%

Influence of Bariatric Surgery on Oral Microbiota: A Systematic Review

Adawi

Aggarwal²,

Jain

et al. 2022

Eur J Dent

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The study aims to systematically review the available literature to evaluate the changes in oral microbiota in patients after bariatric surgery (BS) and correlates these alterations in microorganisms with common oral manifestations. Relevant Electronic databases were systematically searched for indexed English literature. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed for framework designing, application, and reporting of the current systematic review. The focused PICO question was: “Is there any change in oral microbiota (O) of patients (P) who underwent BS (I) when compared with non-BS groups (C)?' Seven articles were selected for qualitative synthesis. On application of the National Institutes of Health (NIH) quality assessment tool, six studies were found to be of fair quality and one was of good quality. All the seven included studies evaluated the effect of BS on oral microbiota in humans. The outcomes of this review suggest that considerable changes take place in oral microbiota after BS which can be correlated with common oral manifestations. These changes are mainly due to the indirect effect of BS and may vary with the individuals. Due to variations in the included studies, it is difficult to proclaim any persistent pattern of oral microbiota found after BS.

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“…4 Several ingredients in Indonesia that can be used to produce liquid smoke include rice husks, 5 coconut shells, 6 7 durian, 8 lamtoro, corn comb, 9 bamboo, 10 and cocoa bean skin. 11 Of these various types of materials, rice husks have been shown to have the potential to treat various diseases, including periodontitis, 12 oral ulcer, 13 14 15 16 diabetes, 17 18 and burn. 19 The liquid smoke rice hull contains phenol, 2-methoxy-phenol, mequinol, 6-octadecenoic acid, oleic acid, and 9-octadecenoic acid 5 that possess the analgesic, 20 anti-inflammation, 14 antibacterial, 12 21 and lower toxicity.…”

Section: Introductionmentioning

confidence: 99%

In Silico Study of Liquid Smoke Rice Husk against COVID-19

Arundina

Frimayanti²,

Surboyo

et al. 2022

Eur J Dent

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Objectives Liquid smoke rice husk has been researched and proved to consist of antibacterial, analgesic, anti-inflammatory, and growth factor stimulatory properties. By these complex properties, the liquid smoke rice hull is able to purpose as a novel coronavirus disease 2019 (COVID-19) inhibitor. The research was conducted to analyze the role of the dominant compound in rice husk liquid smoke against one of the main proteases in complex with inhibitor N3 of COVID-19 and 6LU7 protein data bank (PDB) ID. Material and Methods The Molecular Operating Environment (MOE) 2020.0901 (Chemical computing group) was used to analyzed the interaction. The molecular structure test, including phenol, mequinol, 2-methoxy-phenol, 6-octadecenoic acid, oleic acid, 9-cctadecenoic acid, was chosen. The lopinavir as positive control and 6LU7 as COVID-19 protein were chosen. All the protein analyses were conducted using docking molecular. Result The phenol, 2-methoxy-phenol, mequinol and 9-octadecenoic acid have higher binding free energy that causes difficult to bind to the active site of protein 6LU7 (−3.4758, −3.5509, −3.6845, and −5.0173 kcal/mol, respectively). The minor component of liquid smoke, such as 6-octadecenoic acid and oleic acid, has the binding free energy (−5,5327 and −5,4208 kcal/mol) and more factor of binding presumably as active COVID-19 inhibitor. Conclusion The liquid smoke rice husk has active component like 6-octadecenoic acid and oleic acid are presumably as active COVID-19 inhibitor.

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The Effects of Rice Husk Liquid Smoke in Porphyromonas gingivalis-Induced Periodontitis

Cited by 14 publications

References 32 publications

Nanoparticles of Liquid Smoke Rice Husk Inhibit Porphyromonas gingivalis

Nanoparticles of Liquid Smoke Rice Husk Inhibit Porphyromonas gingivalis

Influence of Bariatric Surgery on Oral Microbiota: A Systematic Review

In Silico Study of Liquid Smoke Rice Husk against COVID-19

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