“…45 A range of study methodologies was reviewed, including random ized controlled trials (RCTs), 25,45,[50][51][52][53] follow-up outcomes of these RCTs, 31,52 pretest/ posttest time series interrupted design, 48,54 a quasiexperimental, 46 and an observational, counterbalanced across-session and infants design. 49 Of the and improved neurologic, motor and behavioral development [29][30][31][32] ), many of the existing studies have varying protocols, are limited to healthy or convalescing preterm infants greater than or equal to 32 weeks' postmenstr ual age (PMA), and are seldom contingent on infant cues. In addition, a consensus is lacking on the type of tactile stimulation that is appropriate for high-risk very preterm infants in a level III NICU.…”