The effects of physical exercise on body fat distribution and bone mineral density in postmenopausal women

Douchi, Tsutomu; Yamamoto, Shinako; Oki, Toshimichi; Maruta, Kuninori; Kuwahata, Riki; Yamasaki, Hideki; Nagata, Yukihiro

doi:10.1016/s0378-5122(00)00094-3

Cited by 34 publications

(25 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Patients will require appropriate assessment of fracture risk with the use of an anti-osteoporotic therapy, including bisphosphonates, if necessary. In addition, regular physical exercise aimed at maintaining BMD and prevention of falling are advised as well as added calcium (1,500 mg) and vitamin D (800 U) daily to reduce bone mineral loss [27,28]. The low incidence of cerebro-and cardiovascular events found in our study is consistent with previous reports showing that anastrozole is associated with reduced risk of thromboembolic and cerebrovascular events compared with tamoxifen [24].…”

Section: Discussionsupporting

confidence: 90%

Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients

Sagara¹,

Kosha

Baba³

et al. 2009

Breast Cancer

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 90%

Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients

Sagara¹,

Kosha

Baba³

et al. 2009

Breast Cancer

Self Cite

View full text Add to dashboard Cite

show abstract

“…Also, proportional soft tissue composition accounting for BMI depends largely on the population measured, and associations differ between study groups. In postmenopausal populations, BMI becomes more dependent on the amount of body fat mass but can be altered to some degree by physical activity and proper nutrition [20,21].…”

Section: Discussionmentioning

confidence: 99%

Muscle Strength and Body Composition Are Clinical Indicators of Osteoporosis

et al. 2012

View full text Add to dashboard Cite

We examined the role of muscle strength, lean tissue distribution, and overall body composition as indicators of osteoporosis (OP) in a pooled sample of 979 Finnish postmenopausal women (mean age 68.1 years) from the Kuopio Osteoporosis Risk Factor and Prevention study. Bone mineral density (BMD) at the femoral neck (FN) and total body composition were assessed by dual-energy X-ray absorptiometry scans. The women (n = 979) were divided into three groups according to WHO criteria, based on FN BMD T score: normal (n = 474), osteopenia (n = 468), and OP (n = 37). Soft tissue proportions, fat mass index (FMI, fat/height²), lean mass index (LMI, lean/height²), and appendicular skeletal muscle mass (ASM, (arms + legs)/height²) were calculated. Handgrip and knee extension strength measurements were made. OP subjects had significantly smaller LMI (p = 0.001), ASM (p = 0.001), grip strength (p < 0.0001), and knee extension strength (p < 0.05) but not FMI (p > 0.05) compared to other subjects. Grip and knee extension strength were 19 and 16 % weaker in OP women compared to others, respectively. The area under the receiver operating characteristic curve was 69 % for grip and 71 % for knee extension strength. In tissue proportions only LMI showed predictive power (63 %, p = 0.016). An overall linear association of LMI (R² = 0.007, p = 0.01) and FMI (R² = 0.028, p < 0.001) with FN BMD remained significant. In the multivariate model, after adjusting for age, grip strength, leg extension strength, FMI, LMI, number of medications, alcohol consumption, current smoking, dietary calcium intake, and hormone therapy, grip strength (adjusted OR = 0.899, 95 % CI 0.84-0.97, p < 0.01), leg extension strength (OR = 0.998, 95 % CI 0.99-1, p < 0.05), and years of hormone therapy (OR = 0.905, 95 % CI 0.82-1, p < 0.05) remained as significant determinants of OP. Muscle strength tests, especially grip strength, serve as an independent and useful tool for postmenopausal OP risk assessment. In addition, lean mass contributes to OP in this age group. Muscle strength and lean mass should be considered separately since both are independently associated with postmenopausal BMD.

show abstract

“…Also, Lin et al stated that weight-bearing exercise had a greater positive effect on BMD than the non-weightbearing exercise (41). Moreover, Douchi et al confirmed that lumbar spine BMD increased significantly in individual studies of strength training with/without endurance exercise training (42). Finally, weight bearing exercise is universally recognized as a major and effective prophylaxis against osteoporosis, to firstly stimulate bone accretion during growth; secondly, to stimulate bone accretion once bone loss has occurred and thirdly, to prevent bone loss (39).…”

Section: Discussionmentioning

confidence: 99%

Aerobic exercise training modulates bone mineral status in patients with chronic obstructive pulmonary disease

El-Kader

Al-Jiffri

2016

Electron J Gen Med

View full text Add to dashboard Cite

Background:Chronic obstructive pulmonary disease (COPD) appears to be associated with low bone mineral density (BMD) due to long-term use of corticosteroids as a result patients with COPD are at risk for osteoporosis-related fractures and worsening pulmonary function. Objective: The present study aimed to measure the effects of treadmill walking exercises on bone mineral status in patients with COPD. Methods: Sixty patients with moderate COPD of both sexes, their age ranged from 45 to 58 years. Subjects were divided into two equal groups: training group (group A) received aerobic exercise training on treadmill for six months, where the second group (B) was considered as a control group who received no exercise training. The program consisted of three sessions per week for six months. Results:The results of this study indicated a significant increase in BMD of the lumbar spine & the radius and serum calcium & significant reduction in parathyroid hormone in group (A), while these changes were not significant in group (B).Also; there was a significant difference between both groups at the end of the study. Conclusion: Treadmill walking exercise training is an effective treatment policy to improve bone mineral status in patients with COPD.

show abstract

The effects of physical exercise on body fat distribution and bone mineral density in postmenopausal women

Cited by 34 publications

References 26 publications

Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients

Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients

Muscle Strength and Body Composition Are Clinical Indicators of Osteoporosis

Aerobic exercise training modulates bone mineral status in patients with chronic obstructive pulmonary disease

Contact Info

Product

Resources

About