The Effects of Nigella sativa (Kalonji) on Lipid Profile in Patients with Stable Coronary Artery Disease in Multan, Pakistan

Effect of Nigella sativa supplementation on human lipids: systematic review

“…Lipid profiles constitute one of the most important factors that can be changed in many diseases and are used to evaluate conditions of the patients and subjects (Mohtashami and Entezari, 2016). In our review, Nigella sativa supplement can change lipid profiles significantly in different conditions (Heshmati et al, 2015;Ibrahim et al, 2014;Qibi et al, 2006;Najmi et al, 2012;Tasawar et al, 2011;Kaatabi et al, 2012;Najmi et al, 2008;Bhatii et al, 2009;Sabzghabaee et al, 2012;Datau et al, 2010;Qidwai W et al, 2009;Dehkordi FR et al, 2008;Bamosa et al, 1997;Ahmed et al, 2012).…”

“…The age range of the participants in trials was 18-yea0rs old. Supplementation with NS oil can significantly improve lipid profile in hyperlipidemic patients with T2DM (Heshmati et al, 2015;Kaatabi et al, 2012;Ahmed et al, 2012), with menopausal women (Ibrahim et al, 2014), with metabolic syndrome (Najmi et al, 2012;Najmi et al, 2008), and with coronary heart disease (Tasawar et al, 2011). However, no complications caused by NS were observed in all studies (Table 2).…”

“…The treatment group showed significant improvement with reference to total xcholestrol, low density lipoprotein, (LDL All studies were clinical trials and have been conducted on different patients and subjects (Heshmati et al, 2015;Ibrahim et al, 2014;Qibi et al, 2006;Najmi et al, 2012;Tasawar et al, 2011;Kaatabi et al, 2012;Najmi et al, 2008;Bhatii et al, 2009;Sabzghabaee et al, 2012;Datau et al, 2010;Qidwai et al, 2009;Dehkordi et al, 2008;Bamosa et al, 1997;Ahmed et al, 2012). Information of these studies is summarized in the table 2.…”

“…The total number of subjects in these trials was 738 from different conditions and diseases as hyperlipidemia in diabetic patients (Heshmati et al, 2015;Kaatabi et al, 2012;Ahmed et al, 2012), menopausal women (Ibrahim et al, 2014), metabolic syndrome (Najmi et al, 2012;Najmi et al, 2008) and coronary heart disease (Tasawar et al, 2011). The duration of the trials was between 2 weeks-3 months.…”

Use of Black Seed (Nigella Sativa L.) Oil in the Management of Hypertensive and Hyperlipidemic Individuals of District Muzaffarabad, Azad Kashmir, Pakistan

“…Its seeds and seeds extracts has been used medicinally for centuries especially in Mediterranean region, Middle-East and Southeast Asia (Rchid et al, 2004;Najmi, et al, 2008). It has tremendous traditional and pharmacological potential in curing a wide range of ailments particularly hypotension (Aqel, 1992) (Tasawar et al, 2011). N. sativa plant has strong antihypertensive effect that significantly lowered down blood pressure and cholesterol (Dehkordi and Kamkhah, 2008).…”