The effects of hypervolemic infusion on microcirculation perfusion of patients during laparoscopic colorectal surgery

Deng, Yunxin; Zhu, Qinglin; Yu, Bo; Jianhui, Jin

doi:10.1097/md.0000000000008612

Cited by 2 publications

(10 citation statements)

References 8 publications

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“…Table 3 shows the results of 16 trials [ 15 – 17 , 21 , 23 , 24 , 27 , 30 , 41 , 47 – 51 , 56 , 57 ] that reported the volume effects of fluids. Lavu et al [ 30 ] compared 3% NaCl to lactated Ringer's solution (LRS) in patients who underwent pancreaticoduodenectomy using the fluid restriction technique and found lower perioperative intake in the 3% NaCl group (278 vs. 315 mL/kg; p value = 0.017) to maintain hemodynamic status.…”

Section: Resultsmentioning

confidence: 99%

“…Deng el al. [21] favored hypertonic NaCl-HES due to a more stable systemic vascular resistance index but Zhu [57] reported no significant differences in the hemodynamics.…”

Section: Quality Of the Included Studiesmentioning

confidence: 99%

“…Vogt et al [51] reported 6% HES 200/0.5 was an economical alternative to 5% human albumin for resuscitation because they had the same volume expansion effects although a lower serum colloid osmotic pressure was reported in the HES group. Two studies [24,48] compared HES 130/0.4 to HES 200/0.5 and found no differences in the hemodynamic parameters, but HES 200/0.5 in one study [21] had a prolonged INR (1.25 ± 0.19 vs. 1.18 ± 0.09; p value<0.05). Ragaller et al [41] reported HES 200 in 7.2% NaCl could restore the hemodynamics faster than HES 200 in 0.9% NaCl using pulmonary capillary wedge pressure guidance.…”

Section: Quality Of the Included Studiesmentioning

confidence: 99%

“…Ragaller et al [41] reported HES 200 in 7.2% NaCl could restore the hemodynamics faster than HES 200 in 0.9% NaCl using pulmonary capillary wedge pressure guidance. Two studies [21,57] compared 4% gelatin to 4.5% NaCl in 7.6% HES 40. Deng el al.…”

Section: Quality Of the Included Studiesmentioning

confidence: 99%

“…Rittoo [46] and Mahmood et al [34] compared HES to gelatin and found that HES 200/0.62 could maintain higher gastric pH. Deng [21] and Zhu [57] compared 4% gelatin to hypertonic NaCl-HES by the acute hypervolemic infusion technique in laparoscopic colorectal surgery. Using the gastric pH value combined with the gastric-arterial CO 2 gradient, Deng [21] reported that hypertonic NaCl-HES was better while data from Zhu [57] supported gelatin.…”

Section: Macrocirculation and Intravascular Volume Effectmentioning

confidence: 99%

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Intravenous Fluid of Choice in Major Abdominal Surgery: A Systematic Review

Noonpradej

Akaraborworn

2020

Critical Care Research and Practice

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Background. Intravenous fluid therapy plays a role in maintaining the hemodynamic status for tissue perfusion and electrolyte hemostasis during surgery. Recent trials in critically ill patients reported serious side effects of some types of fluids. Since the most suitable type of fluid is debatable, a consensus in perioperative patients has not been reached. Method. We performed a systematic review of randomized control trials (RCTs) that compared two or more types of fluids in major abdominal surgery. The outcomes were related to bleeding, hemodynamic status, length of hospital stay, and complications, such as kidney injury, electrolyte abnormality, major cardiac adverse event, nausea, vomiting, and mortality. A literature search was performed using Medline and EMBASE up to December 2019. The data were pooled to investigate the effect of fluid on macrocirculation and intravascular volume effect. Results. Forty-three RCTs were included. Eighteen fluids were compared: nine were crystalloids and nine were colloids. The results were categorized into macrocirculation and intravascular volume effect, microcirculation, anti-inflammatory parameters, vascular permeability, renal function (colloids), renal function and electrolytes (crystalloids), coagulation and bleeding, return of bowel function, and postoperative nausea vomiting (PONV). We found that no specific type of fluid led to mortality and every type of colloid was equivalent in volume expansion and did not cause kidney injury. However, hydroxyethyl starch and dextran may lead to increased bleeding. Normal saline can cause kidney injury which can lead to renal replacement therapy, and dextrose fluid can decrease PONV. Conclusion. In our opinion, it is safe to give a balanced crystalloid as the maintenance fluid and give a colloid, such as HES130/0.4, 4% gelatin, or human albumin, as a volume expander.

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Section: Resultsmentioning

confidence: 99%

“…Deng el al. [21] favored hypertonic NaCl-HES due to a more stable systemic vascular resistance index but Zhu [57] reported no significant differences in the hemodynamics.…”

Section: Quality Of the Included Studiesmentioning

confidence: 99%

Section: Quality Of the Included Studiesmentioning

confidence: 99%

Section: Quality Of the Included Studiesmentioning

confidence: 99%

Section: Macrocirculation and Intravascular Volume Effectmentioning

confidence: 99%

See 3 more Smart Citations

Intravenous Fluid of Choice in Major Abdominal Surgery: A Systematic Review

Noonpradej

Akaraborworn

2020

Critical Care Research and Practice

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Applicability of Monocyte Activation Test for Pyrogen Detection in Succinylated Gelatin Injection

Zheng

Wang

Xiong

et al. 2021

CPA

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Background:: Pyrogens are fever-inducing substances and pyrogen detection is mandatory in parenteral pharmaceuticals. Succinylated Gelatin Injection (SGI) is a biopharmaceutical product containing multi-component and administrated parenterally. Objective: To assess pyrogen in SGI and to evaluate the feasibility of Monocyte Activation Test (MAT) for pyrogen detection in multi-component pharmaceutical product. Method: In the present study, the Bacterial Endotoxin Test (BET) and the Monocyte Activation Test (MAT) were employed to assess pyrogen in SGI. The MAT method was developed on the basis of HL-60/IL-6 assay. HL-60 cells were incubated with lipopolysaccharide (LPS) standards and sample solutions. The endotoxin produced by the incubation, interleukin-6 (IL-6), was measured by ELISA. The MAT method was validated and main parameters were investigated. Finally, the pyrogenicity of SGIs from two different enterprises was determined by the developed MAT method. Results: The BET failed in test for interfering factors and the MAT was proved suitable for the pyrogen detection of SGI. All the products examined showed negative results in pyrogen detection test. Conclusion: The MAT method is feasible in pyrogen detection of SGI. It can be applied in pyrogen detection for quality and safety control of multi-component biological products.

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The effects of hypervolemic infusion on microcirculation perfusion of patients during laparoscopic colorectal surgery

Abstract: Supplemental Digital Content is available in the text

Cited by 2 publications

References 8 publications

Intravenous Fluid of Choice in Major Abdominal Surgery: A Systematic Review

Intravenous Fluid of Choice in Major Abdominal Surgery: A Systematic Review

Applicability of Monocyte Activation Test for Pyrogen Detection in Succinylated Gelatin Injection

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