The Effects of Hazardous Chemical Exposure on Cardiovascular Disease in Chemical Products Manufacturing Workers

Kim, Ki Woong; Won, Yong Lim; Ko, Kyung Sun; Heo, Kyung-Hwa; Chung, Yong Hyun

doi:10.5487/tr.2012.28.4.269

Cited by 17 publications

(12 citation statements)

References 38 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, of the FRS sub-criteria, systolic blood pressure was significantly low, and HDL was significantly high. This is consistent with previous findings that heavy metals increase blood pressure and blood cholesterol levels [ 18 ]. Additionally, it has been found that total cholesterol levels are significantly higher in workers who deal with Pb [ 19 ] and that there is a significant negative correlation between PbB and HDL cholesterol levels [ 20 ].…”

Section: Discussionsupporting

confidence: 94%

Blood Lead Levels and Cardiovascular Disease Risk: Results from the Korean National Health and Nutrition Examination Survey

Park

Jungjin

2021

IJERPH

View full text Add to dashboard Cite

(1) Objective: Lead, a heavy metal that exists commonly in air, soil and crops may cause chronic disease in the cardiovascular system. The purpose of this study is to investigate how blood lead levels affect cardiovascular disease in adults. (2) Study Design and Participants: It is a cross-sectional, descriptive study using data from the Korean National Health and Nutrition Examination Survey (KNHANES). Data from a total of 1929 participants, derived from the KNHANES, conducted by the Korea Centers for Disease Control and Prevention, in 2017, were analyzed using SPSS version 25.0. (3) Measurement: The cardiovascular disease risk was calculated using the Framingham risk score. There was a strong positive correlation between blood lead levels and the Framingham risk score. Furthermore, of the FRS sub-criteria, systolic blood pressure, HDL cholesterol level and total cholesterol level all also showed a significant correlation. (4) Results: We analyzed the correlation between PbB levels and the FRS sub-criteria, including systolic blood pressure, HDL cholesterol level, total cholesterol level and the FRS total. We found a significant positive correlation between PbB levels and systolic blood pressure, FRS total and total cholesterol level (p < 0.05), as well as a significant negative correlation with HDL cholesterol level (p < 0.05). (5) Conclusion: Based on the perception that there is no lower toxicological threshold for blood lead, it is necessary to restrict lead in product manufacturing for the purpose of public health. In addition, it is necessary to be aware of the dangers of exposure to even small amounts of lead in daily life.

show abstract

Section: Discussionsupporting

confidence: 94%

Blood Lead Levels and Cardiovascular Disease Risk: Results from the Korean National Health and Nutrition Examination Survey

Park

Jungjin

2021

IJERPH

View full text Add to dashboard Cite

show abstract

“…Wang et al 41 described the trend of early onset of the Stanford A dissection in 47.95 years of age and 53.37 years of age in the Stanford B dissection, which is consistent with what was observed in our study and could be related to the high levels of smoking among young people and the high levels of pollution in China. 42 , 43 The International Registry of Aortic Dissection (IRAD) demonstrates a mean age of 63 years old for Western patients with Stanford A aortic dissection. 44 …”

Section: Disscusionmentioning

confidence: 99%

Incidence of Branching Patterns Variations of the Arch in Aortic Dissection in Chinese Patients

Tapia

Zhu

et al. 2015

Medicine

View full text Add to dashboard Cite

Several authors have described anatomic variations of the aortic arch in 13% to 20% of the patients who do not have aortic disease. However, few studies have evaluated these patterns in the thoracic aortic dissection (TAD). In the authors’ knowledge, this is the first survey that specifically investigates the frequency of these variations in a broad, nonselected group of Chinese patients with aortic dissection. Furthermore, it compares this group with a group of patients without aortic disease.The objective of this study was to define the variation frequency of the aortic arch branches pattern using the tomographic studies of 525 Chinese patients with a diagnosis of TAD. The Stanford classification was used to set the site of the initial tear of the dissection. In addition, we performed an epidemiological analysis of the aortic arch anatomic variations in TAD, and its possible implications for surgical or endovascular treatment. The general hypothesis proposal asserted that Chinese patients with dissection of the aorta have a similar incidence of variations of the aortic arch to the patients without aortic disease.A retrospective study of cases and controls was carried out using the tomographic studies (CT) of all patients admitted to the First Affiliated Hospital of Zhengzhou University, located at Henan-China, with a confirmed diagnosis of aortic dissection from January 2012 until December 2014. The group of cases consisted of 525 patients: 374 men and 151 women, with a mean age of 52.27 years (range, 20–89). The average age of the patients with Stanford A and B aortic dissection was 49.46 and 53.67, respectively. The control group consisted of 525 unselected patients without TAD who underwent a CT scan of the chest due to other indications. This group consisted of 286 men and 239 women, with a mean age of 53.60 years (range, 18–89). All the patients with aneurysm or dissection were excluded from the control group. We performed a statistical analysis of demographic data.The study found 7 different patterns of the aortic arch on both groups of cases and controls. Within the 525 patients with TAD were observed 85 (16.19%) anatomical variations, while the control group showed 112 variations (21.33%); P = 0.033. The most common anatomical variant was the bovine arch, found in 62 (11.80%) cases of TAD compared with 77 (14.66%) in the control group; P = 0.172. Anatomical variations were observed in 14.32% of the patients with Stanford A dissection and 17.09% of the patients with Stanford B dissection; P = 0.425. Patients with Stanford A dissection showed the pattern of bovine arch in 23 (13.21%) of 174 cases. In contrast, the patients with Stanford B dissection showed it in 39 (11.11%) of 351 cases; P = 0.481. The anatomical variant defined as vertebral artery of direct origin of the aortic arch was more frequent in the patients with Stanford B dissection (5.12%). The patients with Stanford A dissection presented this pattern in 1.14% of the cases; P = 0.025. This study observed an increased frequency of aort...

show abstract

“…Different types of variable risk agents (e.g lifestyle, work environment and their interaction) and non-variable risk agents (e.g sex, age, genes, etc) may be directly/indirectly associated with the prevalence of some diseases (Hong, Pedersen, Brismar, & de Faire, 1997;Kim, Won, Ko, Heo, & Chung, 2012).…”

Section: Exposure Assessmentsmentioning

confidence: 99%

Investigation of hazardous chemicals exposure on some liver function enzymes using serum and saliva of Iraqi's students

Mathkor¹

2017

وقائع المؤتمر

View full text Add to dashboard Cite

To investigate the potential relevance between health problems and working environment conditions in chemical labs, liver enzymes were examined in both sera and saliva of student volunteers, during the last 15 days of September at which they probably exposed to various chemicals over three months in the Iraqi Chemistry Department. The results showed that there was no significant difference in serum activity for both AST and ALP, however, a significant increase in serum ALT level of Z =-2.355 (p < 0.019), before

show abstract

The Effects of Hazardous Chemical Exposure on Cardiovascular Disease in Chemical Products Manufacturing Workers

Cited by 17 publications

References 38 publications

Blood Lead Levels and Cardiovascular Disease Risk: Results from the Korean National Health and Nutrition Examination Survey

Blood Lead Levels and Cardiovascular Disease Risk: Results from the Korean National Health and Nutrition Examination Survey

Incidence of Branching Patterns Variations of the Arch in Aortic Dissection in Chinese Patients

Investigation of hazardous chemicals exposure on some liver function enzymes using serum and saliva of Iraqi's students

Contact Info

Product

Resources

About