The Effects of Gamma Aminobutyric Acid on Growth Hormone Secretion at Rest and Following Exercise

Powers, Michael E.; Borst, Stephen E.; McCoy, Sean C.; Conway, Rachel; Yarrow, Joshua F.

doi:10.1097/00005768-200305001-01500

Cited by 2 publications

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“…Three grams doses of GABA increased HGH levels, but only if taken just before exercise. Without exercise, the GABA had no effect on HGH (Powers et al 2003). If GABA can raise HGH levels, some of it may cross the blood brain barrier, perhaps only after exhausting exercises.…”

Section: Gaba and Human Growth Hormonementioning

confidence: 90%

Review article: health benefits of some physiologically active ingredients and their suitability as yoghurt fortifiers

Fayed

2014

J Food Sci Technol

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The article is concerned with health benefits of two main physiologically active ingredients namely, Isoflavones and γ-Aminobutyric acid, with emphasis on their fitness for fortification of yoghurt to be consumed as a functional food. Isoflavones (ISO) are part of the diphenol compounds, called "phytoestrogens," which are structurally and functionally similar to estradiol, the human estrogen, but much less potent. Because of this similarity, ISO were suggested to have preventive effects for many kinds of hormone-dependent diseases. In nature, ISO usually occur as glycosides and, once deconjugated by the intestinal microflora, the ISO can be absorbed into the blood. At present, it seems convincing their possible protective actions against various cancers, osteoporosis and menopausal symptoms and high levels of blood cholesterol as well as the epidemiological evidence. Γ-Aminobutyric acid (GABA), it is an amino acid that has long been reported to lower blood pressure by intravenous administration in experimental animals and in human subjects. GABA is present in many vegetables and fruits but not in dairy products. GABA was reported to lower blood pressure in people with mild hypertension. It was suggested that low-dose oral GABA has a hypotensive effect in spontaneously hypertensive. Yoghurt beyond its ability to be probiotic food via its culturing with the gut strains, it could further carry more healthy benefits when it was fortified with physiological active ingredients, especially GABA versus ISO preferring, whether, bacteriologically or biochemically, a fortification level of 50 mg ISO/kg or 200 mg GABA/kg.

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Section: Gaba and Human Growth Hormonementioning

confidence: 90%

Review article: health benefits of some physiologically active ingredients and their suitability as yoghurt fortifiers

Fayed

2014

J Food Sci Technol

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“…In regarding to the growth hormone, the oral administration of Gaba was reported to elevate the resting and post-exercise immunoreactive growth hormone and immunofunctional growth hormone concentrations in humans [132]. Moreover, the administration of Gaba is likely to increase the concentrations of plasma growth hormone and the rate of protein synthesis in the rat brain [133,134].…”

Section: Pharmaceutical Properties Of Gabamentioning

confidence: 99%

An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid

2019

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Gamma-aminobutyric acid (Gaba) is a non-proteinogenic amino acid that is widely present in microorganisms, plants, and vertebrates. So far, Gaba is well known as a main inhibitory neurotransmitter in the central nervous system. Its physiological roles are related to the modulation of synaptic transmission, the promotion of neuronal development and relaxation, and the prevention of sleeplessness and depression. Besides, various pharmaceutical properties of Gaba on non-neuronal peripheral tissues and organs were also reported due to anti-hypertension, anti-diabetes, anti-cancer, antioxidant, anti-inflammation, anti-microbial, anti-allergy, hepato-protection, reno-protection, and intestinal protection. Therefore, Gaba may be considered as potential alternative therapeutics for prevention and treatment of various diseases. Accordingly, this updated review was mainly focused to describe the pharmaceutical properties of Gaba as well as emphasize its important role regarding human health.

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The Effects of Gamma Aminobutyric Acid on Growth Hormone Secretion at Rest and Following Exercise

Cited by 2 publications

References 0 publications

Review article: health benefits of some physiologically active ingredients and their suitability as yoghurt fortifiers

Review article: health benefits of some physiologically active ingredients and their suitability as yoghurt fortifiers

An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid

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