“…In addition, the results also indicated the potential effect of flavonoid on extracellular signal-regulated kinases (ERK), c-Jun Nterminal kinases (JNK), p38, p65, IκBα, IκKα/β phosphorylation, and nuclear factor-kappa B (NF-κB) nuclear translocation(Shen, Lin, Jiang, Wang, & Zhu, 2020). In addition, it has been suggested that GABA has antihypertension, anti-diabetes, anti-cancer, antioxidant, anti-inflammation, anti-microbial, anti-allergy, hepatoprotection, reno-protection, and intestinal protection(Ngo & Vo, 2019). A study in islet β-cells has been revealed that GABA potentially exhibited its antidiabetic effects by modulating on PI3K/Akt-dependent growth and survival pathways.…”