The effects of ethanol on the kinetics of toluene in man

Real-time monitoring of respiratory absorption factors of volatile organic compounds in ambient air by proton transfer reaction time-of-flight mass spectrometry

“…However, compared with the mean respiratory AF in this study, Nomiyama and Nomiyama [37] reported significantly lower AFs (30%), while Yu and Weisel [40] reported much higher AFs (64%). For toluene, the results from this study were almost the same as the mean respiratory AFs of 55% and 54% reported by Wallen et al [44] and Wallen et al [46]. The mean respiratory AFs reported by Carlsson [43], Lof et al [47], and Lof et al [48] were all close to 50%, only slightly lower than the 55.9% recorded in this study.…”

Toxicokinetics of toluene in occupationally exposed volunteers.

“…The toxicokinetics of toluene in occupationall y exposed volunteers were compared with data from a previous study of volunteers that had not been exposed earlier (40).…”

“…The toxicokinetics of industrially used organic solvents in man have been focused upon in severallaboratory exposure experiment s (2,3,4,7,20,26,34,37,38,40,41). However, most of these stud ies were carried out with young health y volunteers with no history of occupational exposure to solvents or other agents that could affect the kinetics of the solvent studied.…”

“…588 acid (II ,42). The toxicokinetics of toluene in volunteers that have not been exposed earlier are also known (2,26,34,35,36,38,40).…”

“…From studies on rats and on humans it is well known that drug metabolism is inhibited by acute ethanol into xication (23) and enhanced after chronic ethanol intake (16). Furthermore, drugs , as well as ethanol, have been shown to affect the metabolism of aromatic organic solvents in man (4,21,37,40,43).…”