The Effects of Corn Peptide Ingestion on Facilitating Alcohol Metabolism in Healthy Men

Hepatoprotective Effect of Albumin Peptides from Corn Germ Meal on Chronic Alcohol‐Induced Liver Injury in Mice

“…Table showed that APF4 were rich in hydrophobic amino acids which accounted for 40% of the total amino acids. The Fischer's ratio of APF4 was 3.72, higher than the value reported in the literature (3.15) (Yamaguchi and others ) and its hydrophobic value was 5.1. The characteristics reported above were related to the hepatoprotective activity of CGMAPs.…”

“…According to the results stated above, it was suggested that the hepatoprotective effect of CGMAPs ( M w <1 kDa) is related to its antioxidant activity in vivo . Many reports indicated that the bioactivity of peptides can be affected by many factors such as amino acid composition (Yamaguchi and others ), molecular weight (Yu and others ) and structure (He and others ), and so on. The effect of CGMAPs and its fractions on the blood alcohol metabolism in mice showed that APF4 ( M w <1 kDa) caused a most reduction of BAC.…”

“…Corn gluten meal, a by‐product from the manufacture of corn starch, contains approximately 60% (W/W) protein (Zhuang and others ). It has been reported that corn peptides prepared from corn gluten hydrolysate are bioactive, which has been confirmed to have a protective property against lipid peroxidation (Li and others ) and facilitating alcohol metabolism (Yamaguchi and others ). Zhang and others () reported that corn oligopeptides derived from corn gluten meal by enzymatic hydrolysis, have a protective effect on early alcoholic liver injury in rats.…”

Effect of Low-Frequency Ultrasonic-Assisted Enzymolysis on the Physicochemical and Antioxidant Properties of Corn Protein Hydrolysates

“…But on the other hand, CGM contains a high proportion of hydrophobic amino acids (leucine, alanine, phenylalanine, etc.) [4], which makes it become a potential source for peptides with biological activities such as antioxidant activity [5], antihypertensive effect [6], facilitating alcohol effect [7], and antitumor efficacy [8], while the poor solubility of corn protein and the special structure have created barrier for enzymes to cleave the protein, which seriously limited the functional peptides' release and reduced the corn protein's bioavailability. Therefore, developing a more efficient technique to overcome these problems is of great interest to food scientists all over the world.…”

High performance liquid chromatography (HPLC) fingerprints and primary structure identification of corn peptides by HPLC-diode array detection and HPLC-electrospray ionization tandem mass spectrometry

“…It had been reported that L and A (Ala) contributed considerably to the bioactivity of facilitating alcohol metabolism, and L had better availability. Furthermore, L played an important role in skeletal muscle contraction and generated A as a source of pyruvic acid in muscle to sustain the tricarboxylic acid cycle which was broken by the excessive drinking [6]. Our laboratory had synthesized the peptide fraction of QeLeLePeF using solid phase peptide The primary structures of the CPs were determined and validated by searching the mass spectrometry database of SwissProt.2013.6.27 with the Protein prospector engine provided by the Regents of the University of California, the searching taxonomy was ZEA.…”